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It is beneficial for both investors and companies to avoid the detrimental consequences of overpricing during an initial public offering (IPO). Prospectuses are an important source of information for potential investors. Through Latent Dirichlet Allocation (LDA) we extract topics from the summary section of prospectuses S-1 for companies holding an IPO in the U.S. in 2019-2020. We represent the un
Galektiner är en proteinfamilj som har visats vara aktiv i cancerceller. Proteinet har bland annat funktioner så som utveckling och spridning av cancerceller. För att förhindra proteinets inblandning i cancercellen kan man introducera en inhibitor, som hindrar aktiviteten hos proteinet. Genom att inhibitorn placerar sig i den position där substratet naturligt skulle binda. Inhibitorn tävlar med deGalectins are a family of carbohydrate recognition proteins involved in modulation of cell signaling and cell adhesion. galectin-9 especially is involved in regulation of the immune response. In this work, galectin-9N inhibitors have been designed, synthesized and evaluated. The aim was to synthesize compounds with higher affinity than currently known compounds. Three compounds were synthesized wi
Tax rules may form an impediment to philanthropic initiatives, including innovative activities such as social entrepreneurship and cross-border initiatives. This chapter analyses three specific tax barriers: barriers to cross-border philanthropy, possible barriers as a result of proposed EU corporate income tax harmonization, and barriers to philanthropy in the form of social entrepreneurship. The
This paper examines a few of the fundamental principles in traditional and modern crisis analysis based on models of liquidity risk and moral hazard. The greatest emphasis in placed on moral hazard as it is concluded that this aspect was a central dilemma to the onset of the crisis in Thailand. The theory is analyzed through a Minskian fragility hypothesis and taken further with the Foley model as
I det här arbetet har jag studerat och provat olika metoder som kan användas vid memorering av musik. Syftet var att hitta de metoder som passade min övning bäst och gav mig mer frihet vid mina framträdanden. Jag valde att fokusera på solostycket With för viola av Reine Jönsson som jag ska spela på min examenskonsert. Jag har bland annat utforskat mental övning, memoreringsprocessen, avslappning v
The electron transmission probability in semiconductor heterostructures made of potential barriers whose height, width and separation are modified to follow different Gaussian functions are calculated using the transfer matrix theory. These structures then serve as electron obstacles in thermoelectric devices in order to increase the output power and efficiency. When computing and comparing these
This paper presents a novel on-line approach of merging multiple different predictors of plasma glucose into a single optimized prediction. Various different predictors are merged by recursive weighting into a single prediction using regularized optimization. The approach is evaluated on 12 data sets of type I diabetes data, using three parallel predictors. The performance of the combined predicti
In cold climates all user requirements for footwear (insulation, waterproof, vapour permeability, drying etc.) can’t be met easily due to their conflicting nature. Defining user conditions is important. Cold may be roughly divided into the three ranges (>+5; +5 to 10; < 10 °C). The choice of proper footwear may be based on this approach. It also reduces some of the conflicting user requirements. U
Popular Abstract in Swedish Akut leversvikt medför hög risk för komplikationer orsakade av bakteriesepsis. Hög nivåer av lipopolysackarider (LPS; endotoxin) i det portala blodet kan leda till förhöjd sekretion av pro-inflammatoriska signalsubstanser från leverns Kupffer-celler, vilket har visats vara ett tidigt och viktigt tecken på leverskada. Patogenesen för inflammatorisk tarmsjukdom (?inflammaAcute liver failure is accompanied by a high rate of bacterial septic complications. High portal level of lipopolysaccharide (LPS) can lead to a pronounced secretion by Kupffer cells of pro-inflammatory mediators which have been shown to be early and important mediators of liver injury. Pathogenesis of inflammatory bowel disease (IBD) is complex; involving environmental, genetic, microbial, and im
In this paper, we investigate the impact of spatial coupling on the thresholds of turbo-like codes. Parallel concatenated and serially concatenated convolutional codes as well as braided convolutional codes (BCCs) are compared by means of an exact density evolution (DE) analysis for the binary erasure channel (BEC). We propose two extensions of the original BCC ensemble to improve its threshold an
In HiperAccess, the scheduling problem takes two forms; firstly, the base station reserves capacity on the uplink for the different terminals, and secondly, the terminals schedule their respective traffic in its assigned share of the channel capacity. Further, the base station generally has less and older information than the terminals, hence, the base station and the terminals may act differently
In this paper we develop a number of generic techniques and algorithms in spectral analysis of large linear approximations for use in cryptanalysis. We apply the developed tools for cryptanalysis of ZUC-256 and give a distinguishing attack with complexity around 2236 . Although the attack is only 220 times faster than exhaustive key search, the result indicates that ZUC-256 does not provide a sour
This paper explores a widely employed instrument of regional innovation policy: the innovation incubator. It proposes that incubation approaches are moving away from a ‘traditional’ approach strongly premised on physical infrastructure and high-technology, to a more interactive, participatory and social mode of innovation, in line with broader developments in innovation policy and theory. To pract
We write with great concern in response to the recent systematic review and meta-analysis of cognitive-behavioral therapy (CBT) in pediatric obsessive-compulsive disorder (OCD) by Uhre et al.1 Although the authors’ results consistently support the clinical efficacy of CBT for pediatric OCD, we expect that, much like ourselves, readers will be confused by the discordant and inappropriate conclusion
A 37-year-old man sustained occlusion of the right coronary artery after a bicycle accident with blunt chest trauma over the left scapula. Acute coronary angiography was performed because of chest pain and ST-segment elevation. Despite surgically successful acute revascularization the patient developed a transmural inferior wall infarction. Coronary artery occlusion after blunt chest trauma is rar
The Learning with Errors problem (LWE) is one of the main candidates for post-quantum cryptography. At Asiacrypt 2017, coded-BKW with sieving, an algorithm combining the Blum-Kalai-Wasserman algorithm (BKW) with lattice sieving techniques, was proposed. In this paper, we improve that algorithm by using different reduction factors in different steps of the sieving part of the algorithm. In the Rege
This article examines the literary evidence for a settlement in Phrygia named Leonton Kephalai, i.e. Lions´Heads. According to preserved literary sources, of which there are only three, Leonton Kephalai was an important military stronghold from the Achaemenid period until the end of the Roman Republic, but the settlement may have been occupied for longer. Furthermore, one literary source specifial
