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Nonheme iron enzymes play an important role in the aerobic degradation of aromatic ring systems. Most enzymes can only cleave substrates with electron-rich substituents, e.g., with two hydroxyl groups. However, salicylate 1,2-dioxygenase (SDO) can cleave rings with only a single hydroxyl group. We investigated the oxygen-activation mechanism of the ring fission of salicylate by SDO by computationa
A novel low-complexity detection scheme is proposed for the multiple-input multiple-output (MIMO) single-carrier frequency division-multiple access (SC-FDMA) systems, which is suitable for ASIC implementations. The proposed detection scheme makes an initial estimate of the transmitted signal based on a minimum mean square error (MMSE) frequency domain equalizer (FDE) detector and finds symbols wit
BACKGROUND: Special neck support pillows claiming to improve rest and reduce neck pain are currently being advertised.OBJECTIVE: To test whether neck pillows have any positive effect on neck pain and quality of sleep compared with usual pillows and, if so, to find the optimal characteristics of such a pillow.METHODS: Thirty-seven hospital employees and 18 neck patients were asked to test six neck
We demonstrate a new screening method for obtaining a prostate-specific antigen (PSA) binding aptamer based on an acoustofluidic separation (acoustophoreis) technique. Since acoustophoresis provides simultaneous washing and separation in a continuous flow mode, we efficiently obtained a PSA binding aptamer that shows high affinity without any additional washing step, which is necessary in other sc
Early and accurate diagnosis of intestinal ischemia is important in order to provide rapid and correct treatment and reduce morbidity and mortality rates. Clinical signs and symptoms are often unspecific. This systemic review sums up literature regarding human plasma biomarkers for acute mesenteric ischemia reported during the last ten years. Classic, general markers, including lactate, white cell
This article examines the relationship between theories of the ‘new’ public diplomacy and recent attemptsby foreign ministries in the United Kingdom, United States and Sweden to develop public diplomacystrategies for the early twenty-first century. It provides a summary of policy debates in each nation alongsideanalysis of the evaluation methods that have been designed to support them. The article
IF steel sheets were processed by conventional symmetric and asymmetric rolling (ASR) at ambient temperature. The asymmetry was introduced in a geometric way using differential roll diameters with a number of different ratios. The material strength was measured by tensile testing and the microstructure was analyzed by optical and transmission electron microscopy as well as electron backscatter dif
The electrical properties of ZrO2 and HfO2 gate dielectrics on n-InAs were evaluated. Particularly, an in situ surface treatment method including cyclic nitrogen plasma and trimethylaluminum pulses was used to improve the quality of the high-κ oxides. The quality of the InAs-oxide interface was evaluated with a full equivalent circuit model developed for narrow band gap metal-oxide-semiconductor (
In this article, we endeavour to find a fast solver for finite volume discretizations for compressible unsteady viscous flows. Thereby, we concentrate on comparing the efficiency of important classes of time integration schemes, namely time adaptive Rosenbrock, singly diagonally implicit (SDIRK) and explicit first stage singly diagonally implicit Runge-Kutta (ESDIRK) methods. To make the compariso
Subband adaptive filters have been proposed to speed up the convergence and to lower the computational complexity of time domain adaptive filters. However, subband processing causes signal degradations due to aliasing effects and amplitude distortions. This problem is unavoidable due to further filtering operations in subbands. In this paper, the problem of aliasing effect and amplitude distortion
This article looks to the philosophy of Gilles Deleuze in order to theorize the crucifixion of Jesus as event in early Christian literature. A Deleuzian view on the event is primarily articulated with the distinction between a sequential and a serial understanding of happenings, where the latter forms the basis for singular events. It is argued that Jesus' death i
(Z, Z)-3, 9-cis-6, 7-Epoxyheptadecadiene, and (Z, Z)-6, 9-cis-3, 4-epoxyheptadecadiene were identified by gas chromatography/flame ionization detection-electroantennographic detection (GC/FID-EAD) and coupled gas chromatography-mass spectrometry (GC-MS) from abdominal tip extracts of Tephrina arenacearia (Lepidoptera: Geometridae), an alfalfa pest. In gas chromatography/flame ionization—single sen
BACKGROUND: An artificial neural network (ANNs) is a non-linear pattern recognition technique that is rapidly gaining in popularity in medical decision-making. This study investigated the use of ANNs for diagnostic and prognostic purposes in pancreatic disease, especially acute pancreatitis and pancreatic cancer. METHODS: PubMed was searched for articles on the use of ANNs in pancreatic diseases u
OBJECTIVE : To identify predictors of later study withdrawal among participants active in The Environmental Determinants of Diabetes in the Young (TEDDY) for 1 year. METHODS : Multiple logistic regression was used to discriminate 3,042 children active in TEDDY for the first 3 years from 432 children who withdrew in Years 2 or 3. Predictor variables were tested in blocks-demographic, maternal lifes
Techniques for searching for good quasi-cyclic (QC) LDPC block codes of short and moderate lengths which are suitable for practical purposes are studied. To facilitate implementations only codes whose parity-check matrices having bidiagonal structure of their submatrices and consequently having low encoding complexity are considered. The problem of finding QC LDPC codes with the near-optimum frame
Abstract in UndeterminedSignal detection algorithms providing likelihood informationfor coded spatial-multiplexing multiple-input multipleoutput(MIMO) wireless communication system pose a criticaldesign challenge due to their prohibitively high computationalcomplexity. In this paper, we present a low-complexity soft-outputdetection algorithm by adopting four implementation-friendlyalgorithm-level
