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In this prospective nested case-control study we analyzed the circumferential differences in estimated cortical thickness (Est CTh) of the mid femoral neck as a risk factor for osteoporotic hip fractures in elderly women and men. Segmental QCT analysis of the mid femoral neck was applied to assess cortical thickness in anatomical quadrants. The superior region of the femoral neck was a stronger pr
Human induced pluripotent stem cells (iPSCs) can provide a promising source of midbrain dopaminergic (DA) neurons for cell replacement therapy for Parkinson's disease. However, iPSC-derived donor cells inevitably contain tumorigenic or inappropriate cells. Here, we show that human iPSC-derived DA progenitor cells can be efficiently isolated by cell sorting using a floor plate marker, CORIN. We ind
Recently, we constructed a focused antibody library tailored to interact with haptens. High functionality of this library was demonstrated, as specific binders could be retrieved to a range of different haptens. In the current study we have developed a mutagenesis and selection strategy in order to further fine-tune the hapten binding properties of these antibody fragments. Testosterone was chosen
This paper is a translation of my "Preference Utilitarianism by Way of Preference Change?", in which I revisit Richard Hare’s classical and much discussed argument for preference utilitarianism (Moral Thinking, 1981), which relies on the conception of moral deliberation as a process of thought experimentation, with concomitant preference change. The paper focuses on an apparent gap in Hare’s reaso
Black liquor is a side-stream in the production of kraft pulp. The extraction of lignin and hemicelluloses from black liquor would reduce the load on the recovery boiler and give valuable by-products. Lignin was separated from black liquor by membrane filtration, using one ceramic and three polymeric nanofiltration membranes, with molecular weight cut-offs in the range of 200 Da to 1 kDa. Ultrafil
We explore how two community-based reform models align with the World Bank's World Development Report 2004 accountability framework. Using a qualitative case study of rural Guatemalan primary schools, we examine local governance through interviews with a range of stakeholders. While both reforms appear appropriate according to the World Bank's accountability framework, especially the model giving
Using the metric of channel capacity, three dual-antenna multiple-input multiple-output (MIMO) terminals with adaptive impedance matching were evaluated at LTE Band 13 in four different user scenarios using simulation. Each of the three terminals is equipped with a slot-monopole antenna and a planar inverted-F antenna (PIFA). The slot monopole is fixed at one edge of the chassis, whereas the locat
Open source-baserad utveckling har senaste åren mött ökat intresse och erkännande inom mjukvaruindustrin. Dessa metoder anpassas och implementeras inom olika organisationer, så kallad inner source, vilket innebär att principer och metoder från open source-utveckling tillämpas inom en intern kontext. Detta examensarbete fokuserar på en granskning av IKEAs nuvarande mjukvaruutvecklingsprocesser genOpen source has lately been gaining more traction and recognition in the software industry. The practices are being implemented within various organisations through an approach known as inner source, which involves taking the principles and practices that have been proven effective in open source environments and applying them within an internal context. This thesis focuses on an exploration of I
The use of Electronic Flight Bags (EFBs) have become widespread and common among a majority of commercial airlines in Scandinavia and the United States in recent years. This development was enabled by modernized rules and regulations and the availability of suitable and affordable commercial-off-the-shelf (COTS) devices. This bachelor thesis studied EFB usage and user experience among pilots in com
Convolutional neural networks have in recent years been successfully employed for various image processing tasks, such as filtering noise. There are however relatively few published attempts for processing video in this way. Image processing methods on single images can be applied frame by frame, but often fail to consider continuity and flow between frames. In this master's thesis we construc
Den svenska miljöbalken är ett viktigt verktyg för att kunna minska Sveriges utsläpp av växthusgaser och för att nå ett klimatneutralt Sverige till år 2045. Miljöbalkens tillståndsprövning av miljöfarlig verksamhet kan påverka de åtgärder och försiktighetsmått en verksamhetsutövare ska företa för att få bedriva en verksamhet som medför olägenhet för miljön, såsom utsläpp till luft. Genom att i tilThe Swedish Environmental Code is an important tool for reducing Sweden’s greenhouse gas emissions and the prospect of reaching a climate-neutral state by the year 2045. The Environmental Code’s permit procedure for environmentally hazardous activities can influence the actions and precautionary measures a business operator must undertake when operating an activity that causes inconvenience to the
This paper investigates whether the Blekinge Region in the south-east of Sweden has the prerequisites to adopt a polycentric regional strategy. The Region is facing challenges when it comes to unemployment and dependency ratios with growing numbers of elderly. A possible solution to this could be adopting a regional strategy that would widen the regions labour market areas through a polycentric re
Russia has been issuing passports to Eastern Europe and the South Caucasus since the Soviet dissolution. Most targeted are secessionist regions of former Soviet states, whose populations are now becoming Russian due to passportisation. This has had several effects on the Eastern Neighbourhood, including brain drain, meaning that the highly educated and skilled citizens are emigrating. The brain dr
I Sverige finns en väletablerad marknad för handel med barn för sexuella ändamål. Det är dock väldigt få anmälda brott som leder till åtal eller fällande dom. Detta visar på att barn som faller offer för människohandel inte innehar fullt rättsskydd. Den 1 januari 2020 trädde barnkonventionen i kraft som lag i Sverige, implementeringens primära syfte var att stärka barns rättsliga ställning. SyftetIn Sweden, there is a well-established market for child trafficking for sexual purposes. However, there are very few reported crimes that lead to prosecution or conviction. This shows that children who are victims to human trafficking do not have full legal protection. On January 1st, 2020, the Convention on the Rights of the Child entered into force as law in Sweden. The primary purpose of the im
Brain computer interfaces (BCI) provide ways for the brain to communicate directly with a computer, and are today primarily used as an aid for people with severe movement impairing disorders. In this study a BCI feature extraction method using a combination of spatial filtering and time-frequency (TF) analysis is developed. The features are then classified using a convolutional neural network. A f
Electroencephalography (EEG) is a medical technique for measuring brain activity through several channels connected to the scalp. Interpreting EEG data is a difficult problem because of the large amount of noise contained in the data. Using spectral methods on EEG data can improve the ability to interpret the data, especially using a time-frequency method called the scaled reassigned spectrogram w
This paper studies the bitcoin lending market and the factors explaining loans defaults. No financial intermediation implies that investors are faced directly with the credit risk. This increases information asymmetry at the cost of the lenders, so bitcoin lending platforms try to reduce this negative effect by providing information about the borrowers and their loan requests. Credit grade and int
Coastal protection is vital for protecting infrastructure, coastal environments and human lives against flooding. Building ecient coastal protection requires a good understanding of maximum sea levels which might occur indifferent time periods in the future. Extreme value theory provides a mathematical framework for such analyses. On November 13, 1872 the biggest recorded sea level surge devastat
