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Objective. This study proposes a novel technique for atrial fibrillatory waves (f-waves) extraction and investigates the performance of the proposed method comparing with different f-wave extraction methods. Approach. We propose a novel technique combining a periodic component analysis (PiCA) and echo state network (ESN) for f-waves extraction, denoted PiCA-ESN. PiCA-ESN benefits from the advantag
We report the discovery of TOI-1268b, a transiting Saturn-mass planet from the TESS space mission. With an age of less than 1 Gyr, derived from various age indicators, TOI-1268b is the youngest Saturn-mass planet known to date; it contributes to the small sample of well-characterised young planets. It has an orbital period of P = 8.1577080 ± 0.0000044 days, and transits an early K-dwarf star with
The encapsulation of colloidal lead halide perovskite nanocrystals within silica (SiO2) is one of the strategies to protect them from polar solvents and other external factors. Here, we demonstrate the overcoating of CsPbBr3 perovskite nanocrystals with silica by exploiting the anhydride-induced transformation of Cs4PbBr6 nanocrystals. CsPbBr3@SiO2 core–shell nanocrystals are obtained after (i)
Using molecular simulation to aid in the analysis of neutron reflectometry measurements is commonplace. However, reflectometry is a tool to probe large-scale structures, and therefore the use of all-atom simulation may be irrelevant. This work presents the first direct comparison between the reflectometry profiles obtained from different all-atom and coarse-grained molecular dynamics simulations.
Utilization of spontaneous polarization electric field of ferroelectric materials to realize the spatial separation and fast transfer of photogenerated charges has been regarded as a promising strategy to fabricate highly efficient photocatalysts. Herein, a novel heterostructure is constructed by coupling potassium poly(heptazine imide) (K-PHI) with ferroelectric BaxSr1-xTiO3 (BxST) through a faci
A new plesiosaur partial skeleton, comprising most of the trunk and including axial, limb, and girdle bones, was collected in the lower Sinemurian (Coimbra Formation) of Praia da Concha, near São Pedro de Moel in central west Portugal. The specimen represents a new genus and species, Plesiopharos moelensis gen. et sp. nov. Phylogenetic analysis places this taxon at the base of Plesiosauroidea. Its
In the passive solar water heater, temperature stratification is a valuable thermodynamic parameter for horizontal water storage tanks. This investigation aims to optimize the deflector and numerically study the effects of various deflector lengths and materials on temperature stratification of a horizontal water storage tank during natural convection. Firstly, comparative thermal performances of
FPGAs play an increasing role in the reconfgurable accelerator landscape. A key challenge in designing FPGA-based systems is partitioning computation between processor cores and FPGAs. An appropriate division of labor is difcult to predict in advance and requires experiments and measurements. When an investigation requires rewriting part of the system in a new language or with a new programming mo
In the face of extreme and enduring stressors, a self-protection coping mode can be entered to conserve resources (Conservation of Resources (COR) theory principle 4). Self-protection coping is underexplored in COR theory yet may offer insights about how people deal with the significant challenges posed by work today. We investigate this using a large-group collaborative auto-ethnography (CAE) wit
Syndromic testing for lower respiratory tract infections with BioFire® FilmArray® Pneumonia Panel Plus (BF) detects 27 pathogens with a turn-around-time of one hour. We compared the performance of BF with culture. Samples from 298 hospitalized patients with suspected pneumonia routinely sent for culture were also analyzed using BF. Retrospectively, patients were clinically categorized as having "p
Ex-situ Raman spectroscopy is a well-established method for the structural characterization of soot but necessitates a sampling step before analysis is made. This work studied the potential to perform Raman spectroscopic measurements of soot directly in the combustion exhaust gases, i.e., online Raman measurements. Two types of soot were produced from a Mini-CAST soot generator, one immature with
Preamble: Robotic magnetic navigation (RMN)-guided catheter ablation (CA) technology has been used for the treatment of cardiac arrhythmias for almost 20 years. Various studies reported that RMN allows for high catheter stability, improved lesion formation and a superior safety profile. So far, no guidelines or recommendations on RMN-guided CA have been published. Purpose: The aim of this consensu
Introduction Anorectal malformations (ARMs) are rare birth defects affecting the anorectum and oftentimes the genitourinary region. The management of ARM patients is complex and requires highly specialized surgical and medical care. The European Reference Network eUROGEN for rare and complex urogenital conditions aimed to develop comprehensive guidelines for the management of ARM applicable on a E
Metachromatic leukodystrophy (MLD) is a fatal, progressive neurodegenerative disorder caused by biallelic pathogenic mutations in the ARSA (Arylsulfatase A) gene. With the advent of presymptomatic diagnosis and the availability of therapies with a narrow window for intervention, it is critical to define a standardized approach to diagnosis, presymptomatic monitoring, and clinical care. To meet the
Fluorescence-based multispectral imaging of rapidly moving or dynamic samples requires both fast two-dimensional data acquisition as well as sufficient spectral sensitivity for species separation. As the number of fluorophores in the experiment increases, meeting both these requirements becomes technically challenging. Although several solutions for fast imaging of multiple fluorophores exist, the
Purpose of Review: Osteoarthritis (OA) is the most common forms of arthritis in the general population, accounting for more pain and functional disability than any other musculoskeletal disease. There are currently no approved disease modifying drugs for OA. In the absence of effective pharmacotherapy, many patients with OA turn to nutritional supplements and nutraceuticals, including collagen der
The security analysis of Keccak, the winner of SHA-3, has attracted considerable interest. Recently, some attention has been paid to the analysis of keyed modes of Keccak sponge function. As a notable example, the most efficient key recovery attacks on Keccak-MAC and Keyak were reported at EUROCRYPT’15 where cube attacks and cube-attack-like cryptanalysis have been applied. In this paper, we devel
Analysis of the genomic landscape of prostate cancer has identified different molecular subgroups with relevance for novel or existing targeted therapies. The recent approvals of the poly(ADP-ribose) polymerase (PARP) inhibitors olaparib and rucaparib in the metastatic castration-resistant prostate cancer (mCRPC) setting signal the need to embed molecular diagnostics in the clinical pathway of pat
