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Background: The individual contribution of genes in the HLA region to the risk of developing type 1 diabetes (T1D) is confounded by the high linkage disequilibrium (LD) in this region. Using a novel approach we have combined genetic association data with information on functional protein-protein interactions to elucidate risk independent of LD and to place the genetic association into a functional
Methane (CH4) fluxes 1997-2010 were studied by combining remotely sensed normalised difference water index (NDWI) with in situ CH4 fluxes from Rylekaerene, a high-Arctic wet tundra ecosystem in the Zackenberg valley, north-eastern Greenland. In situ CH4 fluxes were measured using the closed-chamber technique. Regression models between in situ CH4 fluxes and environmental variables [soil temperatur
In this paper, we construct protograph-based spatially coupled low-density parity-check (LDPC) codes by coupling together a series of L disjoint, or uncoupled, LDPC code Tanner graphs into a single coupled chain. By varying L, we obtain a flexible family of code ensembles with varying rates and frame lengths that can share the same encoding and decoding architecture for arbitrary L. We demonstrate
Introduction: Despite the high incidence of appendicitis, the diagnosis is often delayed in children. A delayed diagnosis may lead to perforation and formation of an abscess. The treatment of an appendiceal abscess is still a debatable subject and studies have not agreed on what strategy to use. Some prefer immediate operation, whereas others advocate conservative management with or without interv
Aktiebolag som inte kan finansiera sin verksamhet enbart genom intäkter kan behöva ta in nytt kapital. Som huvudregel sker det genom att aktiebolaget emitterar nya aktier, teckningsoptioner eller konvertibler. Utgångspunkten är att befintliga ägare ska ha företrädesrätt till att teckna det antal av de emitterade värdepapperna som står i proportion till ägarens befintliga innehav. Sådana emissionerCompanies that cannot finance their business through revenue alone may need to raise new capital. As a rule of thumb, the company does so by issuing new shares, warrants or convertibles. The main rule is that existing owners should have preferential rights to subscribe for the number of securities issued in proportion to the owner's existing holdings. Such issues are called preferential issues
The goals of this project are to investigate the viability of using the MyoTM armband developed by Thalmic labs as a tool for myoelectric control of a hand prosthesis as well as investigate whether the armbands ability to record its spatial position and orientation can be used to increase the performance of the prosthesis control program. Using the surface electrodes, gyroscopes and accelerometers
A method is devised that provides authentication and integrity protection for H.264 encoded surveillance video. A digital signature is created at the H.264 Network Abstraction Layer and included in the video stream, providing robustness against video container changes while remaining format compliant for compatibility with software that does not support the signing feature. The signature is create
Ett fullt mekaniskt rotationsbromssystem aktiverat och reglerat av vinkelacceleration har utvecklats av Brillianze Sweden AB. Bromsens användningsområde ska utökas och därför skapades modeller för flerkroppsdynamiska simuleringar i Adams/View. Det är första gången forskning eller simulationer har gjorts på systemet. Det huvudsakliga målet med avhandlingen var att bekräfta och fortsatt undersöka bA fully mechanical rotational brake system activated and regulated by rate of change in angular velocity has been developed by Brillianze Sweden AB. Its field of usage is currently limited and is to be expanded upon. Therefore new models were made to perform multibody dynamics simulations in Adams/View. This is the first time any research or simulations have been made on this specific brake system
Norge drabbas årligen av hundratals jordskred vilket leder till betydande ekonomisk skada och fara för liv. Därför bedriver norska myndigheter och forskningsinstitutioner omfattande forskning om jordskred och vidtar åtgärder för att övervaka, modellera och slutligen mildra konsekvenserna av och förebygga dessa. Som en del av sitt arbete underhåller norska vattenresurs- och energimyndigheten en natNorway experiences hundreds of landslides annually which leads to significant economic losses and poses a threat to human life. Therefore, Norwegian authorities and scientific institutions are conducting extensive research and take measures in the fields of documenting, modelling and ultimately mitigating and preventing landslides. As part of its work, the Norwegian Water Resources and Energy Dire
The recent progress in wearable sensor technology, signal processing and machine learning enables novel applications in fields such as automatic disease symptom tracking and classification. In this project, data from an ongoing Parkinson’s disease study at the Lund University Hospital is gathered and analyzed, and classification models of varying complexity for symptom severity are evaluated. The
As social desirability has not received enough focus when estimating the predictive power of personality in explaining well-being variance, recent accounts of the relationship between ratings of personality and well-being might be overestimated. The current study investigated the influence of social desirability, operationalized as the evaluative factor of personality (i.e., the tendency to react
The urge for more sustainable and environmental-friendly transportation has never been as high as it is today. The demand will probably continue to increase as the knowledge about climate change continues to widen and as the expectations, of mitigation and adaptation measures, intensifies. One sector that is in great need of taking more mitigation and adaptation measures is the transport sector. T
I det svenska straffrättsliga systemet finns en lång tradition av att särbehandla unga lagöverträdare. Den vedertagna ideologiska uppfattning som ligger till grund för särregleringen framhåller att unga har en outvecklad ansvarsförmåga, att de besitter en ökad sanktionskänslighet samt att samhället bör visa tolerans för den unges mognadsprocess. För de yngsta lagöverträdarna måste även hänsyn tas In the Swedish criminal justice system, there is a long tradition of treating young offenders differently than adults. The accepted ideological view that underlies the special regulation emphasizes that young people have an undeveloped capacity for responsibility, that they have a greater sensitivity to punishment and that society should show tolerance for the young person's maturation process
This thesis analyses the spatio-temporal patterns of inequality and income growth in Sweden during the time-period 1990–2016. It aims at answering the question of whether there has been increasing inequalities, if so where and why. The study is motivated by the ongoing debate on regional development in research, public policy and media which frequently raise questions on the ongoing patterns of in
Wireless communication nowadays is playing a vital role in real-life data transmission. This communication can be machine-to-machine or human to machine communication. In each of these categories, reliability and low latency data transmission are critical factors of success transmission in case the number of devices in a certain area increases. In this thesis, I mainly investigate on smart manufac
Adipic acid is considered as the most valuable dicarboxylic acid with industrial use; however, its production is heavily petroleum-based. This non-natural metabolite can be produced de novo through different metabolic pathways, one of which is the alpha-ketoacid elongation pathway. This investigation revolved around the study of the enzyme that catalyses the first +1C elongation reaction of the pa
En advokat bär på kontraktsrättslig grund ett ansvar gentemot sin klient. Om advokaten vållar sin klient skada genom oaktsamhet ska denne ersätta klienten för skadan. Det finns inte någon särskild lag som klargör skadeståndsansvaret för advokater men på bara de senaste två åren har Högsta Domstolen prövat två mål som handlar om advokaters skadeståndsansvar gentemot sina klienter. FörutsättningarA lawyer is, under contract law, liable to his client for any damage caused as a result of careless consulting. If the lawyer causes his client harm through negligence, he must compensate the client for the damage. There is no specific Swedish law that clarifies liability for lawyers, but in the last two years, the Supreme Court has tried two cases that deal with lawyers' liability towards the
