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Great expectations have been raised about neuroprotection of therapeutic hypothermia in patients with traumatic brain injury (TBI) by analogy with its effects after heart arrest, neonatal asphyxia, and drowning in cold water. The aim of this study is to review our present knowledge of the effect of therapeutic hypothermia on outcome in children and adults with severe TBI. A literature search for r
Aerosol particle samples were collected, and the particle size distribution was measured during 1 year at the Zeppelin station (474 m asl) on Svalbard. The chemical constituents, hygroscopicity, and cloud forming properties of the aerosol were analyzed. The aerosol contained mostly sulfate and nitrate during the summer, whereas from September to February the main components were sodium and chlorid
The timing of annual life-history events affects survival and reproduction of all organisms. A changing environment can perturb phenological adaptations and an important question is if populations can evolve fast enough to track the environmental changes. Yet, little is known about selection and evolutionary potential of traits determining the timing of crucial annual events. Migratory species, wh
There are many instruments assessing the wellbeing of staff, but far from all have been psychometrically investigated. When evaluating supportive interventions directed toward nurse assistants in residential care, valid and reliable instruments are needed in order to detect possible changes. The aim of the study was to investigate validity in terms of data quality, construct validity, convergent a
Energy service companies (ESCOs) are often portrayed as important change agents in capturing the opportunity to curb energy demand and mitigate climate change through increased efficiency. Yet, the literature in this area is limited. While many studies analyze economic and environmental savings from energy efficiency programs, far less attention has been devoted to evaluating managerial and other
Background As moderate to severe psoriasis is a systemic disease with large effects on health-related quality of life, generic measures that include overall health, not only skin involvement, are necessary. Knowledge about the relationship between the generic preference-based EuroQol 5D (EQ-5D) and dermatology-specific measures in psoriasis is limited. Objectives To analyse EQ-5D, the Dermatology
The search for new treatments for seizures, epilepsies, and their comorbidities faces considerable challenges. This is due in part to gaps in our understanding of the etiology and pathophysiology of most forms of epilepsy. An additional challenge is the difficulty in predicting the efficacy, tolerability, and impact of potential new treatments on epilepsies and comorbidities in humans, using the a
Popular Abstract in Swedish Hur man värderar resultat av kirurgisk behandling av ländryggens degenerativa åkommor är ett stort, komplext och delvis kontroversiellt ämne. Denna avhandling studerar resultatvärdering med olika metoder och instrument, huvudsakligen baserat på resultat från det nationella svenska ländryggskirurgiregistret. Arbete I. Inventering av befintliga instrument i litteraturen No consensus regarding outcomes assessment in spine patients exists. Health-Related Quality of Life (HRQoL) questionnaires are increasingly used. The objective of this thesis was the evaluation of HRQoL measures before and after lumbar spine surgery, and their relation to other evaluation parameters as well as relevance of differences. The patients included were operated on for lumbar spine disor
Effective treatment of bleeding episodes in hemophilia with high titer inhibitors (HTI) remains a challenge, despite the fact that the therapeutic armamentarium has expanded considerably over the past few years. Treatment safety has improved with the availability of porcine factor VIII (FVIII) and bypassing products such as recombinant factor VIIa (rFVIIa), and plasma-derived activated Prothrombin
The aim of this study was to develop a software program, called Landmarker, which would aid studies of complex anatomical morphometry by simplifying the manual identification of landmarks in 3D images. We also tested its precision on routine magnetic resonance imaging (MRI) scans. To understand human biological variation, there is a need to identify morphological characteristics from the exterior
Despite the widespread dissemination of clinical practice guidelines on the prevention and treatment of cardiovascular disease (CVD), CVD causes one third of deaths worldwide and almost half of all deaths in the developed world. It is therefore likely that, although some aspects of CVD management have improved, there is still a significant shortfall between what is known about CVD prevention and w
Female reproductive success in the unisexual perennial clonal moss Hylocomium splendens was examined by recording, if the segment was reproductive [produced sporophyte(s)] or not, together with several distance-to-male and male density variables, and segment size. This was done for every female segment in a population over a 5 year study period. A high fraction of the population could be sexed bec
This paper examines the professional and scientific views on the social, ethical and legal issues that impact on the provision of genetic services in Europe. Many aspects have been considered, such as the definition and the aims of genetic services, their organization, the quality assessment, public education, as well as the partnership with patients support groups and the multicultural aspects. T
An integrated product recovery system was developed to separate urokinase from the cell culture broth of human kidney cells HT1080. Supermacroporous monolithic cryogels provided ideal matrices with respect to surface and flow properties for use as cell culture scaffold as well as for affinity chromatographic capture step of the enzyme in the integrated system. The urokinase was produced continuous
Preference studies of many different collembolan species have categorised collembolans being selective in their food choice. To clarify whether collembolan food selectivity is related to fitness parameters, three species, Folsomia fimetaria, Protaphorura armata and Heteromurus nitidus, were fed three fungal species, Alternaria infectoria, Mucor hiemalis and Penicillium hordei, representing fungi o
Cyclometalated ruthenium(II) complexes, [Ru II(C~N)(N~N) 2]PF 6 [HC~N=2-phenylpyridine (Hphpy) or 2-(4'-tolyl)pyridine; N~N=2,2'-bipyridine, 1,10-phenanthroline, or 4,4'-dimethyl-2,2'-bipyridine], are rapidly oxidized by H 2O 2 catalyzed by plant peroxidases to the corresponding Ru III species. The commercial isoenzyme C of horseradish peroxidase (HRP-C) and two recently purified peroxidases from
A numerical and analytical investigation is performed on a dissolved air flotation (DAF) pilot tank by using the residence time distribution (RTD) of the conservative dye rhodamine measured with a fluorometer. The experiments are numerically analyzed with regard to the total volume of the DAF tank separation zone in order to detect differences between observed separation zone flow structures in pr
We study deterministic algorithms for the gossiping problem in ad hoc radio networks under the assumption that each combined message contains at most b(n) single messages or bits of auxiliary information, where b is an integer function and n is the number of nodes in the network. We term such a restricted gossiping problem b(n) -gossiping. We show that rootn-gossiping in an ad hoc radio network on
Aim: To update the first version of the European core curriculum to reflect many developments in radiotherapy and educational philosophy that have taken place in the interim period. Materials and methods: The first version of the European core curriculum was reviewed by the Steering Group together with current education programmes from the various member states and taking into account the developm
Methane production from llama and cow manures from the Bolivian high plateau (The "Altiplano") was studied using a parallel reactor set-up consisting of 10 lab-scale biogasifiers. The effects of pressure (495 and 760 mmHg), temperature (11 and 35 degrees C), hydraulic retention time (20 and 50 days), and manure content in the slurry (10%, 20% and 50%) were evaluated with respect to productivity an
