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BACKGROUND: The heterogeneity of Alzheimer's disease (AD) and lack of well-validated markers of non-AD factors (e.g. TDP-43) present a substantial challenge for therapeutics. Our prior work showed discordance between tau (T) and neurodegeneration (N) identified non-AD factors in AD through multi-modality imaging. Here we tried a simplified approach using plasma ptau217 and medial temporal lobe (MT
BACKGROUND: The heterogeneity of Alzheimer's disease (AD) and lack of well-validated markers of non-AD factors (e.g. TDP-43) present a substantial challenge for therapeutics. Our prior work showed discordance between tau (T) and neurodegeneration (N) identified non-AD factors in AD through multi-modality imaging. Here we tried a simplified approach using plasma ptau217 and medial temporal lobe (MT
Importance: Early identification of the likelihood of autism spectrum disorder (ASD) using minimal information is crucial for early diagnosis and intervention, which can affect developmental outcomes. Objective: To develop and validate a machine learning (ML) model for predicting ASD using a minimal set of features from background and medical information and to evaluate the predictors and the util
Populärvetenskaplig sammanfattning: Planera dagsutflykten och upplev mer av Island. Island med sina aktiva vulkaner och stora glaciärer är ett populärt turistmål och antalet turister ökar år från år. Flertalet av de 350 000 utländska turister som årligen besöker Island anländer med flyg till huvudstaden Reykjavik. Från huvudstaden anordnas dagsutflykter genom en rad olika researrangörer. Man kan äIceland with its active volcanoes and big glaciers is a popular place for tourists and the number of tourists increases yearly. The majority of the 350 000 foreign tourists that visit Iceland each year arrive by plane to the capital city Reykjavik. Many different tour operators arrange day tours from the city. One can also plan day tours oneself and use a rental car. Increasing numbers of tourists
Background: We hypothesised that observed annual incidence rates of ANCA-associated vasculitis (AAV) are driven bysporadic short-term, high-intensity rates characterised as clusters of diagnosis events in time. Using data from Ireland, Swedenand Spain, we performed a changepoint analysis to discover time intervals with high and low rates of vasculitis diagnosis.Methods: We recruited 417 patients f
IMPORTANCE Numerous prospective cohort studies have reported a J-shaped association of urinary sodium excretion with cardiovascular events and mortality. OBJECTIVE To study the association between sodium intake and incident atrial fibrillation (AF). DESIGN, SETTING, AND PARTICIPANTS This cohort study included participants in the Ongoing Telmisartan Alone and in Combination with Ramipril Global End
Scope: This European Society of Clinical Microbiology and Infectious Diseases guideline provides evidence-based recommendations to support a selection of appropriate antibiotic use practices for patients seen in the emergency department (ED) and guidance for their implementation. The topics addressed in this guideline are (a) Do biomarkers or rapid pathogen tests improve antibiotic prescribing and
The three short movements in “Aspects of Snow” are united by the theme of snowy landscapes depicted in the poems and also share concentrated musical material. The piece was written in 2012 and premiered the same year by the Malmö Academy of Music Chamber Choir under the direction of Mats Paulsson. Else Lasker-Schüler (1869–1945) was one of the leading German writers in the decades after the turn o
The social sciences have many different understandings of ‘normative power’, but in European Union (EU) studies normative power has three particular meanings. The first meaning of normative power is its emphasis on normative theory, that is, how we judge and justify truth claims in social science. The second meaning of normative power is as a form of power that is ideational rather than material o
Increasing CO₂ emission is considered as the main reason for global warming in the world. One of the reasons for producing CO₂ is using of fossil-based materials in the construction projects. This study intends to assess the using bio-based materials instead of fossil-based materials for the thermal insulation layer of the external walls and roofs. Another focus of this project is using green conc
1 Effects of Deforestation on Tree Diversity and Livelihoods of Local Community: A Case Study from Nepal By Krishna Karkee PO Box: 170 222 00 Lund, Sweden krishna.karkee.142@student.lu.se A thesis submitted to the Lund University International Master’s Programme in Environmental Science (LUMES) in partial fulfillment of the requirements for the degree of Master of Environmental Science Advisor Pro
https://www.lumes.lu.se/sites/lumes.lu.se/files/karkee_krishna.pdf - 2026-06-30
Microsoft Word - Course analysis GEON07 2019.docx 1 Course analysis GEON07 Quaternary Climate and Glaciation History Spring term 2019 General: This year the course was followed by 10 students, nine of which answered the course evaluation (appended below). This means that there is a solid basis for the course analysis. The outcome of the course evaluation is generally very favourable. It is clear t
https://www.geology.lu.se/sites/geology.lu.se/files/geon07_course_analysis_2019.pdf - 2026-06-30
Chiral building blocks are needed for the production of drugs and fine chemicals, which requires the use of several synthetic routes to produce a specific enantiomer of interest. One promising approach to introduce chirality into molecules is the stereo-selective whole cell bioreduction of carbonyl compounds or ketones to the corresponding chiral alcohols. The aim of this thesis was to develop eff
The access to safe and clean drinking water is a major concern throughout the world. Surface water has become the most common source for raw water, when large quantities of groundwater often are inaccessible, and as surface water requires more treatment, simple, cheap and efficient process methods are necessary. Turbidity removal is essential for treatment of surface water and is often carried out
SYDASIEN_2_2019_SLUTLIG_low-res.pdf På flykt efter ändrade klimatet Verklighetsfabriken Vem älskar Modi? Gatuhundar Tidskrift om Indien, Pakistan, Sri Lanka, Bangladesh, Afghanistan, Nepal, Bhutan och Maldiverna #2 2019 Sydasien.se Pris: 75 SEK 2 #2 2019 n redaktör ut, två redaktörer in. Efter nio år som redaktör för Sydasien går jag nu vidare mot nya utmaningar. Jag har i perioder önskat att jag
https://www.sasnet.lu.se/sites/sasnet.lu.se/files/sydasien_2_2019_slutlig_low-res.pdf - 2026-06-30
Chiral building blocks are needed for the production of drugs and fine chemicals, which requires the use of several synthetic routes to produce a specific enantiomer of interest. One promising approach to introduce chirality into molecules is the stereo-selective whole cell bioreduction of carbonyl compounds or ketones to the corresponding chiral alcohols. The aim of this thesis was to develop ef
The history of modern maritime safety legislation at the international level is relatively young. Its beginnings are generally associated with the sinking of the Titanic in 1912, a tragedy that resulted in the adoption by an international conference of the first of what was to become a series of versions (1914, 1929, 1948, 1960, 1974) of the International Convention for the Safety of Life at Sea (
Object. The aim of this study was to determine the bone lead concentration in lead smelters and reference subjects, relate them to the lead concentration in blood (B-Pb) and urine (U-Pb), and to use the measured bone lead to calculate a biological half-life for lead in bone. Method and design. The lead concentration in the second phalanx of the left index finger (bone-Pb) was determined in vivo us
The goal of this thesis is to explore the church father Justin Martyr’s view of the Jewish people and how he interprets their role in salvation history and their relationship with Christians. By applying a discourse analysis on Justin’s work Dialogue with Trypho these themes can be explored. By using a historical-critical lens the thesis aims to explore what Justin’s work originally meant not how
