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Homozygous C2 deficiency (C2D) is the most common deficiency of the classical complement pathway in Western countries. It is mostly found in patients with autoimmune disease or susceptibility to bacterial infections and in healthy persons. We wished to assess to what extent other immunological factors might explain differences of susceptibility to infections in C2D. For this reason, 44 Swedish pat
In anti-glomerular basement membrane (anti-GBM) disease, IgG class autoantibodies induce rapidly progressive glomerulonephritis. Regrettably, many patients are diagnosed at a late stage when even intensive conventional treatment fails to restore renal function The endopeptidase IdeS (Immunoglobulin G degrading enzyme of Streptococcus pyogenes) (imliflidase) rapidly cleaves all human IgG subclasses
We introduce rigorous theory for deriving first and second order backpropagation methods for Deep Neural Networks (DNN) whilst satisfying existing theory in DNN optimization. We begin by formally defining a neural network with its respective components and state the first and second order chain rule with respect to its partial derivatives. The partial derivatives in the chain rule formula are rela
Development plan for the Master’ programme in International Development and Management (LUMID) Page 1 of 7 Faculty Board DEVELOPMENT PLAN STYR 2020/1721 3 February 2022 Development plan for the Master’ programme in International Development and Management (LUMID) Background During 2021, the Faculty of Social Sciences’ Master’s programme in International Development and Management (LUMID) was evalu
https://www.sam.lu.se/en/internal/sites/sam.lu.se.en.internal/files/2022-05/Development-plan-LUMID.pdf - 2026-07-05
This thesis analyzes how and why old toys are restored by and for adults, despite contemporary Western society's understanding of toys as signifiers of childhood exclusively. With this in mind, the intent is to answer whether childhood attachments to toys can also be observed in adults by analyzing how the restoration process of toys reaffirms emotional and social significance for all involved
Preamble: Robotic magnetic navigation (RMN)-guided catheter ablation (CA) technology has been used for the treatment of cardiac arrhythmias for almost 20 years. Various studies reported that RMN allows for high catheter stability, improved lesion formation and a superior safety profile. So far, no guidelines or recommendations on RMN-guided CA have been published. Purpose: The aim of this consensu
https://goteborgonline-my.sharepoint.com/personal/peter_jonsson_educ_goteborg_se/Documents/C%20e%20n%20t%20r%20a%20l%20a%20%20%20S%20a%20c%20o%20r%20å%20d%20e%20t%20%20%20i%20%20%20G%20ö%20t%20e%20b%20o%20r%20g%20s%20%20%20S%20t%20a%20d/AU/SKOT/C%20E%20N%20T%20R%20A%20L%20A%20%20%20S%20A%20C%20O%20R%20Å%20D%20E%20T%20%20%20I%20N%20F%20O%20R%20M%20E%20R%20A%20R/December%202024/www.saco.se/goteborg
The p53 tumor suppressor gene regulates growth arrest and apoptosis after DNA damage. Recent studies suggest that p53 is inactive in vascular smooth muscle cells (VSMCs) in human angioplasty restenosis, promoting VSMC accumulation and vessel stenosis. In contrast, the success of irradiation (brachytherapy) for in-stent restenosis argues that DNA-damage p53 responses are intact. We examined p53 exp
Popular Abstract in Swedish Denna avhandling handlar om modeller för plana solfångare, transparent isolering och verkningsgradsfaktorer. En ekvation för energiutbytet från en glasad plan solfångare härleds genom att modellera verkningsgradsfaktorn, F´, som en summa av en konstant och en temperaturberoende del. Ett alternativt sätt att testa en plan solfångare, baserat på denna modell, föreslås. EThis thesis deals with models of flat plate collectors, transparent insulation and efficiency factors. An equation for the energy output from a glazed flat plate collector is derived by modelling the collector efficiency factor, F´ as the sum of a constant and a temperature dependent part. An alternative way of testing a flat plate collector, based on this model, is suggested. A complete set of a
Progamme evaluation of doctoral education in Service Studies: Statement from external expert group Page 1 of 17 STATEMENT FORM EXTERNAL EXPERT GROUP Reg. No. STYR 2021/1290 2021-10-15 Progamme evaluation of doctoral education in Service Studies: Statement from external expert group Assignment and external expert group The assignment of the external expert group (see composition below) has been to
Sustainable energy storage and conversion explores innovative methods to efficiently store and transform energy from various renewable sources. It focuses on technologies like advanced batteries, hydrogen production, fuel cells, and thermochemical systems as well as safety aspects of battery storage systems. Research aims to enhance energy density, reduce costs, and improve scalability, enabling r
https://www.energy.lth.se/research/energy-storage-conversion - 2026-07-03
The Ordovician Lockne impact structure is located in central Sweden. The target lithology consisted of limestone and black unconsolidated shale overlaying a Precambrian crystalline basement. The Precambrian basement is uranium-rich, and the black shale is both uranium- and organic-rich. This circumstance makes Lockne a good candidate for testing the occurrence of U-Th-rich bitumen nodules in an im
Abstract Purpose: To evaluate the midterm outcomes and potential risk factors associated with the fascia suture technique (FST) for closure of femoral artery access sites after percutaneous endovascular aneurysm repair (EVAR). Methods: Between April 2007 and April 2008, 100 consecutive EVAR cases were evaluated retrospectively. A third of the procedures were emergent (16 ruptured aneurysms). Of th
Time-lapse imaging of Streptomyces hyphae revealed foci of the essential protein DivIVA at sites where lateral branches will emerge. Overexpression experiments showed that DivIVA foci can trigger establishment of new zones of cell wall assembly, suggesting a key role of DivIVA in directing peptidoglycan synthesis and cell shape in Streptomyces.
In this paper we demonstrate the presence of two novel in vivo autophosphorylation sites in the c-Kit/stem cell factor receptor (c-Kit/SCFR): Tyr-703 in the kinase insert and Tyr-936 in the C-terminal tail. We furthermore demonstrate that the adapter protein Grb2 is a specific binding partner for both phosphorylated Tyr-703 and phosphorylated Tyr-936, whereas the adapter protein Grb7 binds selecti
Formerly widely distributed throughout Europe, the great snipe (Gallinago media) – a medium-sized wader species – has experienced an important decline in the last century, mainly driven by habitat loss. Remaining population are now restricted to eastern Europe and Scandinavia and the species is considered endangered. The great snipe (Gallinago media) is a food specialist, feeding almost exclusivel
The development of EU labour and social law has been described as a pendulum in the sense of focus shifting between economic interests, such as competitiveness for industry, and social interests, such as improving working and living conditions. This view is to a large extent based on the presumption that those interests are contrasting and pursuing one of them would necessarily exclude the promoti
