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Background: Multimorbidity and illness will become more common due to increased life expectancy. Purpose: This study describes various combinations of diseases and symptoms and explores implications for survival in a sample of 80 year-olds followed up to 95 years of age. Furthermore, reported subjective health, coping, and life satisfaction is explored. Method: 212 persons, born in 1908, were cl
The performance of a miniaturized sample processing platform for matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS), manufactured by silicon microfabrication, called integrated selective enrichment target (ISET) technology was evaluated in a biological context. The ISET serves as both sample treatment device and MALDI-MS target, and contains an array of 96 perforated nanovial
We present a new approach for the accurate reconstruction of three-dimensional skeletal positions using roentgen single-plane photogrammetric analysis (RSPA). This technique uses a minimum of three markers embedded in each segment which allow continuous, real-time, internal skeletal movement to be measured from single-plane images, provided that the precise distance between the markers is known. A
Extensive microscopic molecular dynamics simulations have been performed to study the effects of short-chain alcohols, methanol and ethanol, on two different fully hydrated lipid bilayer systems (POPC and DPPC) in the fluid phase at 323 K. It is found that ethanol has a stronger effect on the structural properties of the membranes. In particular, the bilayers become more fluid and permeable: ethan
The aggregation behavior of an amphiphilic supramolecular system, with potential application as a tumor-specific magnetic resonance imaging contrast agent, has been studied in detail by dynamic light scattering, small-angle neutron scattering and cryotransmission electron microscopy. The system was constituted of mixed aggregates formed by an anionic unimer containing the DTPAGlu, a chelating agen
The H-1 NMR Fast Field Cycling relaxometry was applied to study the molecular dynamics of the human protein HC (alpha(1)-microglobulin), its hydration and aggregation in solution state. The H-1 NMRD data have revealed the complex nature of the water/protein HC system resulting from the co-existence of monomer and dimer forms of the protein in solution as well as the presence of oligosaccharides li
We demonstrate how rather hydrophilic surfactants can be used for solubilizing simultaneously water and alkane. The required hydrophilic-lipophilic balance can be achieved by the addition of a medium-chain alcohol, that is, a hydrophobic cosurfactant. Specifically, the phase behavior of the quaternary water-n-octane-n-octyl beta-glucopyranoside (C(8)G(1))-n-octanol (C8E0) system has been investiga
In an accompanying paper (Am. J. Epidemiol. 2002;155:1066-73), the authors describe the design of a large multicenter study being carried out in three West African countries for investigation of the roles of environmental and host-related factors in the development of tuberculosis. In this paper, the authors review some evidence that host genetic factors play a role in susceptibility to tuberculos
The acidity and basicity of prereduced V-Ti-O catalysts were measured by adsorption of NH3 and CO2. It was found that a high activity in the ammoxidation of 3-picoline corresponds to a relatively small amount of acidic sites. A catalyst selective in the formation of nicotinonitrile requires high concentrations of both acidic and basic sites. These results are discussed, and can be correlated if th
Future wireless networks, the systems beyond 3G, will be a combination of different wireless systems. With only one terminal a user should be able to connect to different type of operators, technologies and systems. The issue is also to make the terminal staying online connected, when these changes are made. Both intrasystem handovers and intersystem handovers should be supported by such terminals
Abstract in French L'humidité a une influence prépondérante sur un grand nombre de processus d’interaction et de transport qui affectent de manière directe la durabilité, le retrait et le comportement des bétons à haute performance (BHP) soumis à différents types de conditions d’exposition. Une étude expérimentale sur les propriétés de transport d'humidité de 20 mélanges de béton a été effectuée d
Flow maldistribution in plate heat exchangers causes deterioration of both thermal and hydraulic performance. The situation becomes more complicated for two phase flows during condensation where uneven distribution of the liquid to the channels reduces heat transfer due to high liquid flooding. The present study evaluates the thermal performance of falling film plate condensers with flow maldistri
Meteor radar observations carried out in August-September 1953-84 at theOnsala Space Observatory in Sweden show long-term, as well as short termvariations in meteor radar rates. These rate variations are associatedwith position in the solar cycle, and with variations in the solar windsector structure. An inverse correlation is found between meteor radarrates and the solar cycle. The magnitude of t
International research has emphasised the importance of anti-Catholicism for the processes of identity formation across Europe, both for established Protestant Churches and for national liberal movements. The connection between anti-Catholicism and other ‘anti’ movements such as antisemitism, anti-feminism, and anti-socialism has also been pointed out. Much like these movements, anti-Catholicism w
