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Lipid droplets play a central role in energy storage and metabolism on a cellular scale. Their core is comprised of hydrophobic lipids covered by a surface region consisting of amphiphilic lipids and proteins. For example, high and low density lipoproteins (HDL and LDL, respectively) are essentially lipid droplets surrounded by specific proteins, their main function being to transport cholesterol.

Abstract in UndeterminedWithin cognitive linguistics, there is an increasing awareness that the study of linguistic phenomena needs to be grounded in usage. Ideally, research in cognitive linguistics should be based on authentic language use, its results should be replicable, and its claims falsifiable. Consequently, more and more studies now turn to corpora as a source of data. While corpus-based

Plants have a remarkable capacity to adapt to local environmental conditions, which can result in ecotypic differentiation. Patterns of differentiation can, however, also be influenced by the extensive phenotypic plasticity exhibited by many plant species. In this study, we evaluated the distinctness of two putative ecotypes of the parasitic herb Rhinanthus angustifolius. We compared population me

Hematopoietic stem cells (HSCs) reside and self-renew in the bone marrow (BM) niche. Overall, the signaling that regulates stem cell dormancy in the HSC niche remains controversial. Here, we demonstrate that TGF-beta type II receptor-deficient HSCs show low-level Smad activation and impaired long-term repopulating activity, underlining the critical role of TGF-beta/Smad signaling in HSC maintenanc

Current cardiovascular risk scores do not include obesity or fat distribution as independent factors, and may underestimate risk in obese individuals. Assessment of early vascular ageing (EVA) biomarkers including arterial stiffness, central blood pressure, carotid intima-media thickness and flow-mediated vasodilation may help to refine risk assessment in obese individuals in whom traditional card

Two-dimensional polarization fluorescence imaging of single light harvesting complexes 2 (LH2) of Rps. acidophila was carried out to investigate the polarization properties of excitation and fluorescence emission simultaneously, at room temperature. In two separate experiments we excited LH2 with a spectrally narrow laser line matched to the absorption bands of the two chromophore rings, B800 and

It is argued in this paper that the nature of innovation networks can vary substantially with regard to the type of knowledge that is critical for innovation. Subject to the knowledge base of an industry, networks between companies can differ in various aspects, such as their geographical configuration, their structure, the type of actors holding a strategic position and the type of relations betw

The European Spallation Source (ESS) is a neutron science facility funded by a collaboration of 17 European countries currently under design and construction in Lund, Sweden. The centerpiece of ESS is a 2.5 GeV proton linac utilizing superconducting RF cavities operating at 2 K. In addition to cooling the SRF cavities, cryogenics is also used at ESS in the liquid hydrogen moderators surrounding th

The most recent fashion in the policy-level promotion of excellence in academic research seems to be the launching of funding programs directed to young and promising (postdoc level) researchers with the purpose of assisting them in establishing their own research profile at this allegedly crucial and fragile career stage. In the Swedish public research funding system, which is rather diversified

The aim of this study was to gain knowledge about the specific needs that a web-based support system for young carers (YCs) must meet. Twelve young people with experience of caring for and supporting a close friend, partner or relative with mental illness (MI) were interviewed about their life situation, support needs and opinions about a hypothetical web-based support system. The transcribed inte

An accurate characterization of the microstructure of raw and pure homoionic clays from Wadi Bashira in Iraq (IQ-WB) has been carried out experimentally, using small-angle X-ray scattering (SAXS) and dynamic light scattering. The structures of lamellar IQ-WB dispersions were identified by these techniques and by complementary free swelling and dialysis experiments. SAXS measurements were used to r

Witnesses' event recall and the realism in their evaluation of the correctness of their recall are of great importance in forensic processes. These issues were investigated in the present study by use of calibration methodology. More specifically, we analyzed the effects of two recalls of the same event (repetition) and of probes (non-informative follow-up questions at recall) on 9-11 year-old chi

Some 30 years ago it was suggested that catalytic reactions that showed a 'compensation' effect were activated through a vibrational resonance between that one vibrational mode of the reactant that led to reaction and a comparable vibration mode of the catalyst system that represented the energy input. The isokinetic effect can be calculated from this model, in some cases within less than 1 % from

Purpose of review Obesity has significant impact on asthma incidence and manifestations. The purpose of the review is to discuss recent observations regarding the association between obesity and asthma focusing on underlying mechanisms, clinical presentation, response to therapy and effect of weight reduction. Recent findings Clinical and epidemiological studies indicate that obese patients with a

Abstract in UndeterminedTargeted proteomics via selected reaction monitoring (SRM) is a powerful mass spectrometric technique affording higher dynamic range, increased specificity and lower limits of detection than other shotgun mass spectrometry methods when applied to proteome analyses. However, it involves selective measurement of predetermined analytes, which requires more preparation in the f

Cluttering is a fundamental problem in 3D city model visualization. In this paper, a novel method for removing cluttering by typification of linear building groups is proposed. This method works. in static as well as dynamic visualization of 3D city models. The method starts by converting building models in higher Levels of Details (LoDs) into LoD1 with ground plan and height. Then the Minimum Spa