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The Manchester Short Assessment of Quality of Life (MANSA) is a short interview, which has received a recent interest in research investigating quality of life in people with mental illness. In the present study, the Swedish version of MANSA is examined with regard to reliability, in terms of internal consistency and construct validity. Ninety-two persons with severe mental illness were interviewe

The formation of nanostructures with controlled size and morphology has been the focus of intensive research in recent years(1-10). Such nanostructures are important in the development of nanoscale devices and in the exploitation of the properties of nanomaterials(9). Here we show how tree-like nanostructures ('nanotrees') can be formed in a highly controlled way. The process involves the self-ass

Ammoxidation of 3-picoline to nicotinonitrile was studied on V2O5, V6O13, and V2O4 catalysts in a fixed-bed integral reactor. The activity studies showed that V6O13 was the most active and selective catalyst of the pure oxides, with a maximum yield of 76% nicotinonitrile at 365 °C. The maximum yield on V2O5 catalyst was 34%, and was obtained at a higher temperature, 458 °C. V2O4 was found to be in

The spermine analogue N(1),N(11)-diethylnorspermine (DENSPM) efficiently depletes the polyamine pools in the breast cancer cell line L56Br-C1 and induces apoptotic cell death via the mitochondrial pathway. In this study, we have over-expressed the anti-apoptotic protein Bcl-2 in L56Br-C1 cells and investigated the effect of DENSPM treatment. DENSPM-induced cell death was significantly reduced in B

In polymorphic male painted dragon lizards (Ctenophorus pictus), red males win staged contests for females over yellow males, and yellow males have greater success in staged sperm competition trials than red males. This predicts different reproductive strategies in the wild with red males being more coercive or better mate guarders than yellow males. Yellow males would be expected to sire more off

Communication over the copper twisted-pair channel is performed by transmitting and receiving differential-mode (DM) signals. In this paper, we extend the conventional DM receiver scheme by incorporating the common-mode (CM) signal, which is strongly correlated with the DM signal and can be extracted at the end of every wire pair. The wireline channel, including the CM receive signal, is modelled

Simultaneous saccharification and fermentation (SSF) of wood has been modeled for the past 15-20 years, but the substrates used for model evaluation have so far not included pretreated softwood. In the present study, data from lab-scale batch SSF of SO2-impregnated, steam-pretreated spruce chips were used to evaluate a model found in the literature. The model, which was somewhat modified, consists

We tested two predictions of the hypothesis that competition between self-pollen may mitigate negative genetic effects of inbreeding in plants: (1) intense competition among self-pollen increases offspring fitness; and (2) pollen competition reduces the measured strength of inbreeding depression. We used Collinsia heterophylla (Plantaginaceae), an annual with a mixed mating system, to perform cont

The genetic variation in a partially asexual organism is investigated by two models suited for different time scales. Only selectively neutral variation is considered. Model 1 shows, by the use of a coalescence argument, that three sexually derived individuals per generation are sufficient to give a population the same pattern of allelic variation as found in fully sexually reproducing organisms.

Neurogenin 2 (Ngn2) is a proneural gene involved in neuronal differentiation and subtype specification in various regions of the nervous system. In the ventral midbrain, Ngn2 is expressed in a spatiotemporal pattern that correlates with the generation of mesencephalic dopaminergic (mesDA) neurons. We show here that lack of Ngn2 impairs the development of mesDA neurons, such that less than half of

Chromosomal aberrations in solid tumors appear in complex patterns. It is important to understand how these patterns develop, the dynamics of the process, the temporal or even causal order between aberrations, and the involved pathways. Here we present network models for chromosomal aberrations and algorithms for training models based on observed data. Our models are generative probabilistic model

Objective - To study factors of importance for participation in parental education within routine child health care. Design - All parents of children born during 1 year were invited by the district nurse to participate in parental education; their participation during the infant year was registered. Setting - Catchment area of two health centres in Vaxjo, Sweden. Subjects - 221 infants and their p

The RUNX1 gene encodes the alpha subunit of the core binding factor (CBF) and is a common target of genetic mutations in acute leukemia. We propose that RUNX1 is a gatekeeper gene, the disruption of which leads to the exodus of a subset of hematopoietic progenitors with increased self-renewal potential from the normal environmental controls of homeostasis. This pool of "escaped" cells is the targe

The rheological properties of wormlike micellar solutions formed by the pseudo-ternary system sodium dodecyl sulfate (SDS)-Al(NO3)(3)-H2O have been studied at a fixed molar ratio Al(NO3)(3):SDS = 5.92:1 as a function of surfactant concentration. The linear data show that solutions behave as a Maxwell fluid and there are two well-defined domains characterized by scaling laws for surfactant concentr

This paper introduces a new algorithmic technique for solving certain problems in geometric computer vision. The main novelty of the method is a branch-and-bound search over rotation space, which is used in this paper to determine camera orientation. By searching over all possible rotations, problems can be reduced to known fixed-rotation problems for which optimal solutions have been previously g