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L-lactate dehydrogenase (LDH) from Bacillus stearothermophilus is a redox enzyme which has a strong preference for NADH over NADPH as coenzyme. To exclude NADPH from the coenzyme-binding pocket, LDH contains a conserved aspartate residue at position 52. However, this residue is probably not solely responsible for the NADH specificity. In this report we examine the possibilities of altering the coe

The atrioventricular (AV) node plays an important role during atrial fibrillation (AF). In particular, the refractoriness of its cells influences the conduction of atrial impulses to the ventricles and, thus, the ventricular response. This study introduces a novel statistical model of the AV node, accounting for pathway switching, which can be used for non-invasive assessment of the refractory pro

Objective: Reconstruction with deep inferior epigastric perforator flap (DIEP) is considered to be the first choice for autologous breast reconstruction. The primary aims of this retrospective study were to find out if differences in smoking habits and BMI are useful predictors for postoperative complications in DIEP surgery. Methods: Three hundred and one patients were included. Data regarding sm

The present contribution presents event-related potential (ERP) and functional magnetic resonance imaging (fMRI) findings related to the processing of Swedish word accents. These results are then discussed and further analysed in the context of models of word activations and phonological neighbourhoods. It has previously been seen that word accents (either a low tone (accent 1) or a high tone (acc

In most of the world, borehole heat exchangers used with closed-loop ground source heat pump systems are backfilled with a low permeability grout to prevent water contamination. However, in Scandinavian countries, a different approach is taken – the borehole is sealed at the top and cased down to solid bedrock. The borehole then naturally fills with groundwater in the annular space between the U-t

Conditions for nurses’ daily patient education work are unclear and require clarification. The aim was to develop and validate the Nurses’ Patient Education Questionnaire, a questionnaire that assesses nurses’ perceptions of appropriate conditions for patient education work: what nurses say they actually do and what they think about what they do. The questionnaire was developed from a literature r

Systems with many integrated circuits (ICs), often of the same type, are increasingly common to meet the constant performance demand. However, systems in recent semiconductor technologies require not only manufacturing test, but also in-field test. Preferably, the same test set is utilized both at manufacturing test and in-field test. While deterministic test patterns provide high fault coverage,

The ultrastructure of the upper tibial epiphyseal plate during the development of acute, experimental scurvy in the guinea pig was investigated. The cartilage was examined after the animals had been maintained, under standardized conditions, on a scorbutogenic diet for 8, 15, or 23 days. Progressive fine structural changes were observed in the experimental animals. Within the chondrocytes, the cis

Popular Abstract in Swedish Många har frågat mig vad mitt doktorandprojekt egentligen handlar om. Mitt svar brukar variera beroende på hur insatt personen ifråga är. Normal brukar jag börja med ungefär följande förklaring: I våra kroppar finns proteiner som hjälper till att utföra och reglera kemin som krävs för att hålla de biologiska processerna igång. Att förstå denna kemi kan vara till hjälp

Lattice Boltzmann method (LBM) is an alternative to conventional CFD to capture the detailed activities of the transport processes at microscale. Here LBM is used to model the hydrogen production by splitting water by incident sunlight over water covered Si-nanorods. The purpose of this study is, by a 3D microscale model, to investigate the transport and the formation of the hydrogen bubbles by el

Extreme Programming (XP) is becoming popular as a software development method and there is quite a lot of literature describing its philosophy and practices. However, in all of this literature Software Configuration Management (SCM) is almost never mentioned explicitly, leaving XP practitioners with the impression that SCM is not needed and SCM people with the impression that XP is not sound from

Extreme Programming (XP) is becoming popular as a software development method and there is quite a lot of literature describing its philosophy and practices. However, in all of this literature Software Configuration Management (SCM) is almost never mentioned explicitly, leaving XP practitioners with the impression that SCM is not needed and SCM people with the impression that XP is not sound from

Development/Plasticity/Repair MicroRNA-124 Is a Subventricular Zone Neuronal Fate Determinant Malin Åkerblom,1 Rohit Sachdeva,1 Isabelle Barde,2 Sonia Verp,2 Bernhard Gentner,3 Didier Trono,2 and Johan Jakobsson1 1Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, 221 84 Lund, Sweden, 2School of Life Sciences, École Polytechnique

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/8879.full_.pdf - 2026-05-28

SCIENCE AND PROVEN EXPERIENCE JOHANNES VETENSKAP OCH BEPRÖVAD ERFARENHET VID SBU | 1 2 | STEN ANTTILA & SUSANNA AXELSSON SCIENCE AND PROVEN EXPERIENCE JOHANNES ISBN 978-91-983575-5-4 © The VBE Research Program and the Authors Graphic design Johan Laserna Printed by Media-Tryck, Lund University, Lund 2018 Preface 9 NILS-ERIC SAHLIN A note on randomized controlled trials in evidence-based medicine 1

https://www.vbe.lu.se/sites/vbe.lu.se/files/vbe_johannes.pdf - 2026-05-28