Search results

Granule neurons of the dentate gyrus (DG) of the hippocampus undergo continuous renewal throughout life. Among cell cycle regulators, cyclin-dependent kinase 2 (Cdk2) is considered as a major regulator of S-phase entry. We used Cdk2-deficient mice to decipher the requirement of Cdk2 for the generation of new neurons in the adult hippocampus. The quantification of cell cycle markers first revealed

We report on the use of a sacrificial AlAs segment to enable substrate reuse for nanowire synthesis. A silicon nitride template was deposited on a p-type GaAs substrate. Then a pattern was transferred to the substrate by nanoimprint lithography and reactive ion etching. Thermal evaporation was used to define Au seed particles. Metalorganic vapour phase epitaxy was used to grow AlAs-GaAs NWs in the

To overcome the large discrepancy in speed between computational devices and that of contemporary large capacity non-volatile memory (NVM) technologies, resistive random access memory (RRAM) technologies are seen as promising candidates, offering speed/energy improvements in several orders of magnitude while being 3D integration compatible [1]. Indium-Tin-Oxide (ITO) has several unique properties

Aims To investigate predictors of hangover during a week of heavy drinking in young adults. Design Observational prospective study. Methods A total of 112 young Danish tourists were interviewed on three occasions during their holiday. They completed the Acute Hangover Scale and answered questions about their alcohol consumption and rest duration. The incidence of hangover was analysed as the propo

Cracks in concrete structures can have a negative impact on durability and aesthetic appearance. It is therefore important to estimate crack widths before construction, and to use suitable reinforcement amounts to limit crack widths. Crack widths are however hard to predict in restrained structures, as cracking reduces the stiffness, which in turn reduces the restraint and thereby the amount of cr

Purpose: The purpose of this paper is to develop a theory of enterprise risk management (ERM). Design/methodology/approach: The method is to develop a theory for ERM based on identifying the general risk management problems that it is supposed to solve and to apply the principle of deduction based on these premises. Findings: ERM consists of risk governance, which is a set of mechanisms that deals

Reaching and grasping impairments significantly affect the quality of life for people who have experienced a stroke or spinal cord injury. The long-term well-being of patients varies greatly according to the restorable residual capabilities. Electrical stimulation could be a promising solution to restore motor functions in these conditions, but its use is not clinically widespread. Here, we introd

We examine how the gender of a sibling affects earnings, education and family formation. Identification is complicated by parental preferences: if parents prefer certain sex compositions over others, children's gender affects not only the outcomes of other children but also the existence of potential additional children. We employ two empirical strategies that both address this problem. First, we

Accessibility throughout society has been gaining interest at the international as well as the national level. According to Swedish legislation, public environments should be accessible to all citizens by the year 2010. This paper focuses on older pedestrians, and aims at investigating how accessibility is dealt with and carried out in the municipal process of traffic planning: “accessibility in p

Ducts of various geometrical cross sections appear extensively in engineering applications like heat exchangers. In the available literature analytical, numerical and experimental data are available for the friction factor and the Colburn factor for a variety of thermal boundary conditions. Results for fully developed cases are commonly available, but also for the thermally and hydrodynamically de

Background: Global climate change is already increasing the average temperature and direct heat exposure in many places around the world. Objectives: To assess the potential impact on occupational health and work capacity for people exposed at work to increasing heat due to climate change. Design: A brief review of basic thermal physiology mechanisms, occupational heat exposure guidelines and heat

Abstract in UndeterminedHeat has for long been utilised as a therapeutic tool in medicine. Tumour diseases and vascular malformations can be treated by elevating the temperature to cytotoxic levels. Laser-induced heat treatment relies on the conversion into heat of light absorbed in the tissue. Mathematical models were used to calculate the light absorption distribution and the subsequent temperat

A diversity of softwood lignin depolymerization processes yield guaiacol as the main low molecular weight product. This key aromatic compound can be utilized as a carbon source by several microbial species, most of which are Gram positive bacteria. Microbial degradation of guaiacol is known to proceed initially via demethylation to catechol, and this reaction is catalyzed by cytochrome P450 monoox

Swedish municipalities have traditionally had significant powers and played a major role in implementing national energy strategies. This paper describes the factors influencing development of municipal climate and energy plans in five Swedish municipalities and assesses the relevance and importance of these factors from theoretical and practical perspectives. The questions raised in the paper are

Studies conducted in historical populations and developing countries have evidenced the existence of clustering in infant deaths, which could be related to genetic inheritance, early life exposures, and/or to social and cultural factors such as education, socioeconomic status or parental care. A transmission of death clustering has also been found across generations. This paper is one of five stud