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A cinefluorographic study of uvular consonants in Swedish and West Greenlandic. Poster presented at the conference From Sound to Sense

This poster concerns the articulation of uvular consonants with particular reference to quantal aspects of speech production. Data from X-ray motion films are presented. Two speakers of Southern Swedish give examples of [R], and one speaker of West Greenlandic Inuit gives examples of [R] and [q]. Traditionally, uvular consonants are said to be produced by articulating the dorsum against the uvula.

Decreased levels of intrathecal interleukin 1 receptor antagonist in Alzheimer's disease

A growing body of evidence points out the potential role of inflammatory mechanisms in the pathophysiology of brain damage in dementia. In previous studies, we have demonstrated intrathecal production of the proinflammatory cytokine tumor necrosis factor (TNF)alpha in patients with Alzheimer's disease (AD). The aim of the present study was to investigate the downstream products of TNF-alpha expres

Evolution of pistil length as a choice mechanism for pollen quality

During the fertilisation process in plants, pollen tube growth rate may be selected as a trait important in male to male competition. Since female morphology provides the necessary selective arena for such competition. we investigate if sexual selection theory can be used to explain the evolution of pistil length as a female choice mechanism. This choice is performed by direct interference with ma

VATER non-random association of congenital malformations: study based on data from four malformation registers

This study was undertaken to find a strict, unbiased epidemiological delineation of the VATER non-random association of congenital malformations and, based on registry information, to identify a group of probable VATER association infants suitable for etiological analyses. Information on 5,260 infants with multiple malformations was collected from four large registers of congenital malformations.

An imaging system for monitoring receptive field dynamics

The paper describes a computerized method, termed receptive field imaging (RFI), for the rapid mapping of multiple receptive fields and their respective sensitivity distributions. RFI uses random stimulation of multiple sites, in combination with an averaging procedure, to extract the relative contribution from each of the stimulated sites. Automated multi-electrode stimulation and recording, with

Prevention of arthropathy: may it be extrapolated from patients without inhibitors to patients with inhibitors?

Although no consensus on the exact dosing schedule of prophylaxis in non-inhibitor haemophilia patients has been achieved, regular administration of factor VIII (FVIII) or factor IX (FIX) concentrates is currently accepted as the most effective treatment model in order to prevent sick days, hospital stays and the development of arthropathy in patients with severe haemophilia. The basis for prophyl

Laminar thermal performance of microchannel heat sinks with constructal vertical Y-shaped bifurcation plates

With increasing output power of integrated chips, the involved heat flux is accordingly increased. Traditional cooling methods failed to satisfy such a situation, and thus new cooling methods incorporating microchannel heat sinks with high capabilities of heat removal are necessary. In this paper, on the basis of a water-cooled smooth microchannel heat sink, vertical Y-shaped bifurcation plates ar

Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression

Lymphatic vessels (LVs) play critical roles in the maintenance of fluid homeostasis and in pathological conditions, including cancer metastasis. Although mutations in ALK1, a member of the transforming growth factor (TGF)-beta/bone morphogenetic protein (BMP) receptor family, have been linked to hereditary hemorrhagic telangiectasia, a human vascular disease, the roles of activin receptor-like kin

Immunochip analysis identifies multiple susceptibility Loci for systemic sclerosis.

In this study, 1,833 systemic sclerosis (SSc) cases and 3,466 controls were genotyped with the Immunochip array. Classical alleles, amino acid residues, and SNPs across the human leukocyte antigen (HLA) region were imputed and tested. These analyses resulted in a model composed of six polymorphic amino acid positions and seven SNPs that explained the observed significant associations in the region

Impact of temperature dependent sampling procedures in proteomics and peptidomics – A characterization of the liver and pancreas post mortem degradome

Little is known about the nature of post mortem degradation of proteins and peptides on a global level, the so-called degradome. This is especially true for non-neural tissues. Degradome properties in relation to sampling procedures on different tissues are of great importance for the studies of for instance post translational modifications and/or the establishment of clinical biobanks. Here, snap

Positive patch test reactions to oxidized limonene: exposure and relevance

Background. R-Limonene is a common fragrance terpene found in domestic and industrial products. R-Limonene autoxidizes on air exposure, and the oxidation products can cause contact allergy. In a recent multicentre study, 5.2% (range 2.3-12.1%) of 2900 patients showed a positive patch test reaction to oxidized R-limonene. Objective. To study the exposure to limonene among consecutive dermatitis pat

Velarium control and visual steering in box jellyfish.

Directional swimming in the box jellyfish Tripedalia cystophora (cubozoa, cnidaria) is controlled by the shape of the velarium, which is a thin muscular sheet that forms the opening of the bell. It was unclear how different patterns of visual stimulation control directional swimming and that is the focus of this study. Jellyfish were tethered inside a small experimental tank, where the four vertic