Filetype
Popular Abstract in Swedish Avhandlingen behandlar den svenska fotbollens kulturhistoria från 1800-talets slut fram till år 1950. Det är berättelsen om hur spelet gradvis etableras, överkommer en mängd inre och yttre problem och konflikter, för att träda in i sin guldålder under 1940-talet. Mer konkret följs hur fotbollens medelklassdominerade maktelit försökte kontrollera skeendet inom en sport p
Popular Abstract in English Among the forms of life found in extreme environments (e.g. high temperatures ‘thermo’ and oxygen deficient ‘anaerobe’), the thermoanaerobic bacteria emerge as a highly evolved and interesting subject of study. Bacteria living as microbial mats in decaying plant material possess a great potential not only to degrade complex biomass but also to produce special chemicals.A novel ethanol-producing thermoanaerobe Caloramator boliviensis 45BT (=DSM 22065T, =CCUG 57396T) was isolated from a hot spring of the Bolivian highlands. C. boliviensis possesses the ability to utilize a wide range of substrates and can efficiently convert hexoses and pentoses into ethanol with concomitant production of acetate, carbon dioxide and hydrogen as by-products of fermentation. However
Popular Abstract in Swedish Sår som inte läker utgör ett betydande problem för dem som drabbas och för sjukvården i stort. Utebliven eller defekt läkning är ofta ett led i en bakomliggande sjukdom som exempelvis diabetes, förlamningstillstånd eller olika bindvävs- och kärlsjukdomar. Förutom en mycket stor ekonomisk belastning för sjukvården, så innebär det ett stort fysiskt och psykiskt lidande fö
Popular Abstract in Swedish Bindväv är ett samlingsnamn för vävnader som ger form och struktur i olika organ i kroppen. I brosk och ben utgör bindväven hela eller stora delar av organet, medan i andra organ, t.ex. muskel, är bindväven endast en liten del. Bindväv karaktäriseras av ett nätverk av proteiner och polysackarider (extracellulär matrix), som omger och produceras av en relativt liten andeThis thesis describes the structure and interactions of a novel extracellular matrix protein - PRELP (proline arginine-rich end leucine-rich repeat protein). The amino acid sequence of PRELP showed that it belonged to the leucine-rich repeat (LRR) protein family in connective tissues. The main part of PRELP is composed of 10 LRRs flanked by disulfide bridges at the amino- and carboxy-terminal end
Popular Abstract in English Proteins are molecular machines of the human body which regulate all life sustaining processes such as energy production, communication, transport of essential molecules, defense against microbes, etc. They are built by small molecular units called amino acids, bound together like pearls on a necklace. Each amino acid consists of a common part and a unique side chain. TAnisotropic protein interactions have a strong orientation dependence resulting from an uneven distribution of charged and hydrophobic residues on the protein surface. They play an important role in protein behaviors such as protein association, surface adsorption and phase separation. In this thesis, we have studied the effect of anisotropic interactions on the behavior of various proteins mainly
Popular Abstract in Swedish Under de senaste 20 åren har större hänsyn tagits till den enskilde patientens önskningar och behov innan en behandling har påbörjats. Detta har skett parallellt med en snabb teknisk och medicinsk utveckling. Samtidigt som nya behandlingsmetoder tagits fram, har det också blivit angeläget att utvärdera effekten av dessa, vilket även inkluderar hur den enskilde individen
Oats is an important cereal used for both food and feed. The topic of this thesis is the annotation of the genome of oat (Avena sativa) cv. Sang, as well as some of the things this genome and its annotation have been used for.The first part of the thesis provides a short background to oat genomic resources, genomic resources in other plant species, and assembly of cereal genomes. Following this, i
Urban building energy models present a valuable tool for promoting energy efficiency in building design and control, as well as for managing urban energy systems. However, the current models often overlook the importance of site-specific characteristics, as well as the spatial attributes and variations within a specific area of a city. This methodological paper moves beyond state-of-the-art urban
Triple-negative breast cancer (TNBC) is the most lethal subtype of breast cancer with high heterogeneity and poor therapeutic responses to standard treatments. The use of herbal medicine for treatment of TNBC is gaining in popularity worldwide due to their better anti-tumor efficacy and less side effects compared to chemotherapy agents. Previous studies have shown that crocin, a natural carotenoid
In 2018, the International Organization for Migration stated that ‘migration has nearly become synonymous with urbanization, given the dominance of the city as the destination of most migrants’. The geopolitical dimension of migration governance is especially important in Mediterranean cities where the European Union’s (EU) efforts to push border management onto external actors has occurred alongs
The impact of CO dilution on combustion of syngas (a mixture of H2, CO, and CH4) was investigated in a lab-scale gas turbine model combustor at atmospheric pressure conditions. Two mild dilution levels of CO2, corresponding to 15% and 34% of CO2 mole fraction in the syngas/CO2 mixtures, were experimentally investigated to evaluate the effects of CO2 dilution on the flame structures and the emissio
Rationale: The optimal duration of dual antiplatelet therapy (DAPT) with clopidogrel-aspirin for the large artery atherosclerotic (LAA) stroke subtype has been debated. Aims: To determine whether the 1-year risk of recurrent vascular events could be reduced by a longer duration of DAPT in patients with the LAA stroke subtype. Methods and study design: A total of 4806 participants will be recruited
The extent to which newly developed blood-based biomarkers could reduce screening costs in secondary prevention trials of Alzheimer's disease is mostly unexplored. We collected plasma amyloid-β42/40, apolipoprotein E ϵ4 status and amyloid PET at baseline in 181 cognitively unimpaired participants [the age of 72.9 (5.3) years; 61.9% female; education of 11.9 (3.4) years] from the Swedish BioFINDER-
Context dependence arises when ecological relationships vary with the conditions under which they are observed. Context dependence of interactions involving parasites is poorly known, even if it is key to understanding host–parasite relationships and food web dynamics. This paper investigates to which extent predation pressure on an avian ectoparasite (Carnus hemapterus) is context-dependent. Base
The Swedish Childhood Tumor Biobank (BTB) is a nonprofit national infrastructure for collecting tissue samples and genomic data from pediatric patients diagnosed with central nervous system (CNS) and other solid tumors. The BTB is built on a multidisciplinary network established to provide the scientific community with standardized biospecimens and genomic data, thereby improving knowledge of the
We discuss the sequence of developments that over the past 90 years led to current insights on heavy-element stability. The semi-empirical mass model, and its extension to deformed shapes, developed in the period 1936–1950 allowed the interpretation of nuclear fission. Around 1950 the spherical single-particle model was developed, soon after with extension to deformed nuclei. Speculations about a
The production of the W± bosons measured in p–Pb collisions at a centre-of-mass energy per nucleon–nucleon collision sNN = 8.16 TeV and Pb–Pb collisions at sNN = 5.02 TeV with ALICE at the LHC is presented. The W± bosons are measured via their muonic decay channel, with the muon reconstructed in the pseudorapidity region −4 < ηlabμ < −2.5 with transverse momentum pTμ > 10 GeV/c. While in Pb–Pb col
Habitat loss and population fragmentation pose severe threats to biodiversity and the survival of many species. Population isolation and the decline in effective population size lead to increased genetic drift and inbreeding. In turn, this reduces neutral diversity, and it also affects the genetic load of deleterious mutations. Here, we analyse the effect of such genomic erosion by designing a spa
Speciation entails a reduction in gene flow between lineages. The rates at which genomic regions become isolated varies across space and time. Barrier markers are linked to putative genes involved in (processes of) reproductive isolation, and, when observed over two transects, indicate species-wide processes. In contrast, transect-specific putative barrier markers suggest local processes. We studi
