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II INTERNATIONAL CONFERENCE ONRADIOECOLOGICAL CONCENTRATION PROCESSES : II INTERNATIONAL CONFERENCE 50 years later

From the 6th to the 9th of November 2016, in the meeting hall of Centro Nacional de Aceleradores(University of Seville, Seville, Spain) took place the “II International Conference onRadioecological Concentration Processes (50 years later)” under the joint organization of theUniversities of Seville (Spain) and Gothenburg (Sweden). With this event, the organization try tocommemorate the fifty years

Human Primary Bone Marrow Mesenchymal Stromal Cells and Their in vitro Progenies Display Distinct Transcriptional Profile Signatures

Bone marrow mesenchymal stromal cells (BM-MSCs) are a rare population of cells that gives rise to skeletal tissues and the hematopoietic stroma in vivo. Recently, we have demonstrated that BM-MSCs fulfill stringent in vivo stem cell criteria when propagated as non-adherent mesenspheres but not as adherent-cultured cells. Motivated by these profound functional differences, the current study aimed t

Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes

Objective: Non-coding RNAs constitute a major fraction of the β-cell transcriptome. While the involvement of microRNAs is well established, the contribution of long non-coding RNAs (lncRNAs) in the regulation of β-cell functions and in diabetes development remains poorly understood. The aim of this study was to identify novel islet lncRNAs differently expressed in type 2 diabetes models and to inv

Type 2 diabetes, glucose, insulin, BMI, and ischemic stroke subtypes : Mendelian randomization study

Objective: To implement a mendelian randomization (MR) approach to determine whether type 2 diabetes mellitus (T2D), fasting glucose, fasting insulin, and body mass index (BMI) are causally associated with specific ischemic stroke subtypes. Methods: MR estimates of the association between each possible risk factor and ischemic stroke subtypes were calculated with inverse-variance weighted (convent

Humanitarian supply chain strategies – a review of how actors mitigate supply chain risks

Purpose: The purpose of this paper is to link humanitarian logistics (HL) and supply chain risk management (SCRM) to provide an understanding of risk mitigation strategies that humanitarian organisations use, or could use, to improve their logistics preparedness. Design/methodology/approach: Based on systematic reviews of RMS in SCRM and supply chain strategies (SCS) in HL literature, a framework

Pancreastatin plasma levels in patients with primary hyperparathyroidism

Pancreastatin, a C-terminally amidated peptide derived from chromogranin A, is known to inhibit insulin secretion, pancreatic enzyme release, and gastric acid secretion. It also inhibits parathyroid hormone (PTH) secretion in animals. The physiologic and clinical relevance of pancreastatin in humans, however, is not known. Because pancreastatin has been found in parathyroid adenomas, we investigat

An 'alpha-beta' of pancreatic islet microribonucleotides

MicroRNAs (miRNAs) are cellular, short, non-coding ribonucleotides acting as endogenous posttranscriptional repressors following incorporation in the RNA-induced silencing complex. Despite being chemically and mechanistically very similar, miRNAs exert a multitude of different cellular effects by acting on mRNA species, whose gene-products partake in a wide array of processes.Here, the aim was to

Autofluorescence guided biopsy for the early diagnosis of bladder carcinoma

Purpose We validate the usefulness of laser-induced autofluorescence for the detection of bladder carcinoma. Materials and Methods We obtained and analyzed fluorescence spectra from 75 patients in whom bladder cancer was suspected. Tissue fluorescence was excited by a nitrogen laser using a quartz optical fiber placed in gentle contact with the area of interest. The laser-induced autofluorescence

Rat retinal ganglion cells upregulate the pro-apoptotic BH3-only protein Bim after optic nerve transection

Increased expression of Bim, a pro-apoptotic member of the Bcl-2 family, has been shown to be critical for neuronal apoptosis. To study the involvement of Bim in injury-induced cell death in retina, Bim expression was studied in normal rat retina and in retina after optic nerve transection using quantitative RT-PCR and immunohistochemistry. As a complement to this, the apoptotic regulators Bax, Bc

Culture and personality disorders : Self-harm in Sweden: A national response with treatment implications for those with or without borderline perso- nality disorder

Objectives: The purpose of this presentation is to discuss Sweden’s national recommendations for mental health treatment provided to self-harming individuals in the country. The recommendations were based upon a Self-Harm Quality Standard (2013) published by the National Institute for Health and Care Excellence (NICE) adapted to Swedish health care and cultural context. Methods: A review and synt

Discordant neural tissue xenografts survive longer in immunoglobulin deficient mice

BACKGROUND: The immune response against discordant xenografts in the brain is incompletely understood and remains a major obstacle for future clinical applications of xenogeneic neural tissue transplants in neurodegenerative disorders. To determine the role of antibodies in the rejection process, we compared graft survival and immune reactions between immunoglobulin deficient (IgKO) and normal mic

Transplantation of fetal dopamine neurons in Parkinson's disease : one-year clinical and neurophysiological observations in two patients with putaminal implants

Ventral mesencephalic tissue from aborted human fetuses (age, 6-7 weeks' postconception) was implanted unilaterally into the putamen using stereotaxic surgery in 2 immunosuppressed patients (Patients 3 and 4 in our series) with advanced idiopathic Parkinson's disease. Tissue from 4 fetuses was grafted to each patient. Compared with our previous 2 patients, the following changes in the grafting pro

The chemical compositions of solar twins in the open cluster M67

Stars in open clusters are expected to share an identical abundance pattern. Establishing the level of chemical homogeneity in a given open cluster deserves further study as it is the basis of the concept of chemical tagging to unravel the history of theMilkyWay.M67 is particularly interesting given its solar metallicity and age as well as being a dense cluster environment.We conducted a strictly

Swedish adolescent girls in special residential treatment : A person-oriented approach to the identification of problem syndromes

The purpose of this series of three cross-sectional studies was to identify typical syndromes of self-reported externalizing and internalizing problems, and examine their overlap, among adolescent girls and young women in Swedish special residential homes for young people (N = 713). The associations with some family background factors were also investigated. Data came from a research register at t

Ultra-high-speed PLIF imaging for simultaneous visualization of multiple species in turbulent flames

In order to obtain more detailed characteristics and information in highly turbulent flames, for a better understanding of the transient behavior of eddies in such flames, a measurement technique with sufficient temporal resolution is requested. However, the probing of species distributions relevant in combustion (e.g. OH, CH2O) with ultra-high-speed laser diagnostics still remains a challenge. Nd

Estimation of Coulomb stress changes and induced earthquake occurrences prediction in the region of Three Gorges Reservoir, China

In the region of Three Gorges Reservoir (TGR) in China, there has been occurrence of several frequent earthquakes of moderate intensity since reservoir impounding occurred in 2003. These earthquakes are generally believed to be induced by reservoir impoundment and water-level variations. Usually, the geo-stress will change, when natural earthquakes occur. Following this principle, this paper adopt

Surgical treatment of patients with unilateral cerebellar infarcts : clinical outcome and prognostic factors

BACKGROUND: There are limited data on the long-term outcome and on factors influencing the prognosis in patients with cerebellar infarcts treated with surgical decompression.METHODS: Thirty-two patients (age 64.3 ± 9.9 years) with expansive unilateral cerebellar infarcts were retrospectively evaluated. All patients were treated with ventriculostomy, suboccipital decompressive craniectomy and remov

New market labor and obesity : A nation-wide Italian cross-sectional study

Objectives: To investigate the prevalence of obesity among different types of employment status in the Italian working population, and to examine associated risk factors. Material and Methods: Cross-sectional survey of 36 814 people that declared to have been occupied with the same type of contract for at least 5 years was analyzed. Multivariable logistic regression models were built considering w