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Popular Abstract in Swedish Genom observationer och experiment kan man konstruera modeller för att beskriva otaliga fenomen och aspekter av det universum vi lever i. Den huvudsakliga ingrediensen i en dylik modell är ofta en partiell differentialekvation. Sådana ekvationer kan beskriva så vitt skilda fenomen som t.ex. hur galaxer bildas, hur luftflöden transporteras i atmosfären, hur kemikalier reThis thesis is based on five papers, which all analyse different aspects of splitting schemes when applied to nonlinear parabolic problems. These numerical methods are frequently used when a problem has a natural decomposition into two or more parts, as the computational cost may then be significantly decreased compared to other methods. There are two prominent themes in the thesis; the first con

An unprejudiced revision of the genus Pilosella (Asteraceae) in the Nordic countries has been attempted. A completely new system for the taxonomy of these mostly facultative apomicts is presented. It is argued that all existing systems are inappropriate in the light of the complicated, and largely unknown, reproductive biology of these taxa. Previous systems have either treated these taxa as oblig

High-dose exposure to inorganic mercury in man can influence the immune system and in rare cases cause immune-related disease. Some experimental animals also react with autoimmunity after low doses of inorganic mercury. Glomerulonephritis and an increased formation of immunoglobulin type E (IgE) are characteristic of these reactions. A recent study of 15-year-old adolescents demonstrated an associ

Popular Abstract in Swedish Hela livscykeln för en elektronikvara är förknippad med miljöpåverkan. I jämförelse med många andra varor är tillverkningen av elektronik och i synnerhet halvledarkomponenter mycket resurskrävande. Elektroniken ger också upphov till ett antal mycket giftiga utsläpp och avfallsströmmar, såväl från själva tillverkningen som från de uttjänta varorna. Elektronikindustrin ha

The thesis is focused on an attempt to delay photoreceptor cell death in the rd1 mouse using Lens Epithelium Derived Growth Factor (LEDGF), Glutathione S-Transferase mu (GST-?? and Glutathione S-Transferase alpha (GST-?? in an organ culture paradigm as well as the role of metalloproteases (MMPs) and their tissue inhibitors in photoreceptor degeneration (TIMPs). The rd1 mouse model displays a reti

The filamentous fungus Hypocreajecorina (anamorph of Trichodermareesei) is the predominant source of enzymes for industrial saccharification of lignocellulose biomass. The major enzyme, cellobiohydrolase Cel7A, constitutes nearly half of the total protein in the secretome. The performance of such enzymes is susceptible to inhibition by compounds liberated by physico-chemical pre-treatment if the b

BACKGROUND: Sexual conflict theory predicts sexually antagonistic coevolution of reproductive traits driven by conflicting evolutionary interests of two reproducing individuals. Most studies of the evolutionary consequences of sexual conflicts have, however, to date collectively investigated only a few species. In this study we used the annual herb Collinsia heterophylla to experimentally test the

Chondroadherin, a leucine rich repeat extracellular matrix protein with functions in cell to matrix interactions, binds cells via their α2β1 integrin as well as via cell surface proteoglycans, providing for different sets of signals to the cell. Additionally, the protein acts as an anchor to the matrix by binding tightly to collagens type I and II as well as type VI. We generated mice with inactiv

The concept of historical consciousness has been central in didactic research since the early 1990’s. It has been focused in Swedish history curricula, especially since 1994. Historical consciousness has mostly been used on a macro-level as a theoretical framework. This study aims to analyze whether Swedish history textbooks for lower secondary school have articulated contexts that may develop his

Popular Abstract in Swedish Inom medicin, och inom många andra tillämpningar, är uppgiften ofta att utifrån en serie observationer ge ett jakande eller nekande svar på en viss fråga. Exempelvis måste en läkare avgöra om en patient med bröstsmärtor lider av akut hjärtinfarkt eller inte. Artificiella neurala nätverk är en sorts datorprogram som själv förmår "lära" sig att svara på sådana frågor. NäArtificial neural network (ANN) and combinatorial optimization algorithms are developed, and applied to the medical domain. A novel method for training an ensemble of ANN is presented, based on random weight updates alternated with replication of networks with low error. The evolution of the ensemble is explored, with particular emphasis on its diversity and internal correlation. The performance

The concept "declaration of legal intent" belongs to the legal tradition of most European countries. Different versions of a theory pertaining to the declaration of legal intent have been elaborated, all with a view to rendering the concept itself more precise: what conception of "intent" or "will" (counterparts of the latter word being used in several languages, for instance the Swedish viljef