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RIFM fragrance ingredient safety assessment, carbonic acid, 2-hydroxypropyl (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, CAS registry number 260781-16-6
RIFM fragrance ingredient safety assessment, ω-pentadecalactone, CAS Registry Number 106-02-5
RIFM fragrance ingredient safety assessment, pyridine, 4-ethenyl-, reaction products with 3a,4,7,7a-tetrahydrodimethyl-4,7-methano-1H-indene, CAS Registry Number 125352-06-9
RIFM fragrance ingredient safety assessment, 2-decanone, CAS Registry Number 693-54-9
The existing information supports the use of this material as described in this safety assessment. 2-Decanone was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from read-across analog 2-heptanone (CAS # 110-43-0) show that 2-decanone is not expected to be ge
RIFM fragrance ingredient safety assessment, undecane, CAS Registry Number 1120-21-4
RIFM fragrance ingredient safety assessment, propyl propionate, CAS Registry Number 106-36-5
Summary: The existing information supports the use of this material as described in this safety assessment. Propyl propionate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data show that propyl propionate is not genotoxic. Data on propyl propionate provide a
RIFM fragrance ingredient safety assessment, nonanoic acid, CAS Registry Number 112-05-0
RIFM fragrance ingredient safety assessment, indole, CAS Registry Number 120-72-9
RIFM fragrance ingredient safety assessment, 2-phenylpropionaldehyde, CAS Registry Number 93-53-8
Summary: The existing information supports the use of this material as described in this safety assessment. 2-Phenylpropionaldehyde was evaluated for genotoxicity, repeated dose toxicity, developmental and reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data on read-across analogs 3-phenylbutanal (CAS # 16251-77-7)
RIFM fragrance ingredient safety assessment, 3,6-dihydro-4-methyl-2-phenyl-2H-pyran, CAS Registry number 60335-71-9
RIFM fragrance ingredient safety assessment, α-methyl-1,3-benzodioxole-5-propionaldehyde, CAS Registry Number 1205-17-0
RIFM fragrance ingredient safety assessment, 2-(1-methylpropyl)-1-vinylcyclohexyl acetate, CAS Registry Number 37172-02-4
RIFM fragrance ingredient safety assessment, phenylacetaldehyde, CAS Registry Number 122-78-1.
The existing information supports the use of this material as described in this safety assessment. The material (phenylacetaldehyde) was evaluated for genotoxicity, repeated dose toxicity, developmental and reproductive toxicity, local respiratory toxicity, phototoxicity, skin sensitization, and environmental safety. Data show that phenylacetaldehyde is not genotoxic and provide a calculated margi
RIFM fragrance ingredient safety assessment, butyl methacrylate, CAS Registry Number 97-88-1
RIFM fragrance ingredient safety assessment, isobutyl formate, CAS Registry Number 542-55-2
RIFM fragrance ingredient safety assessment, furfuryl thioacetate, CAS Registry Number 13678-68-7
Furfuryl thioacetate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data show that furfuryl thioacetate is not genotoxic. The repeated dose, reproductive, and local respiratory toxicity endpoints were evaluated using the threshold of toxicological concern (TTC