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RIFM fragrance ingredient safety assessment, 1-(3,3-dimethylbicyclo[2.2.1]hept-2-yl)ethane-1-one, CAS Registry Number 42370-07-0
RIFM fragrance ingredient safety assessment, cis-3-hexenyl isovalerate, CAS Registry Number 35154-45-1
RIFM fragrance ingredient safety assessment, methyl-2,2-dimethyl-6-methylene-1-cyclohexanecarboxylate, CAS Registry Number 81752-87-6
The existing information supports the use of this material as described in this safety assessment. Methyl-2,2-dimethyl-6-methylene-1-cyclohexanecarboxylate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data show that methyl-2,2-dimethyl-6-methylene-1-cyclohex
RIFM fragrance ingredient safety assessment, phenol, CAS Registry Number 108-95-2
RIFM fragrance ingredient safety assessment, 3-octanol, CAS Registry Number 589-98-0
Summary: The existing information supports the use of this material as described in this safety assessment. 3-Octanol was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data from read-across analog 3-hexanol (CAS # 623-37-0) show that 3-octanol is not expected to
RIFM fragrance ingredient safety assessment, 3,3,5-trimethylcyclohexyl acetate, CAS Registry Number 67859-96-5
RIFM fragrance ingredient safety assessment, 2-nonanone, CAS Registry Number 821-55-6
RIFM fragrance ingredient safety assessment, N-lactoyl ethanolamine, CAS Registry Number 5422-34-4
RIFM fragrance ingredient safety assessment, 2,5,7-octatrien-1-ol, 2,6-dimethyl-, 1-acetate, CAS Registry Number 197098-61-6
RIFM fragrance ingredient safety assessment, benzene, 1,3,5-trimethoxy-, CAS Registry Number 621-23-8
RIFM fragrance ingredient safety assessment, 4-tert-butyltoluene, CAS Registry Number 98-51-1
Stretch increases alveolar type 1 cell number in fetal lungs through ROCK-Yap/Taz pathway
Accurate fluid pressure in the fetal lung is critical for its development, especially at the beginning of the saccular stage when alveolar epithelial type 1 (AT1) and type 2 (AT2) cells differentiate from the epithelial progenitors. Despite our growing understanding of the role of physical forces in lung development, the molecular mechanisms that regulate the transduction of mechanical stretch to