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Climate change is affecting all regions of the globe, causing a shift of temperature distributions. As species try to track their optimal thermal conditions, they are also potentially met with new photic environments. Photoperiod is the main cue for synchronizing migratory birds' circannual rhythms, affecting both their physiology and migration. Thus, their ability to incorporate and adjust to
Both studies on animals and humans have demonstrated the role of inflammatory mediators on the retinopathy process.2,3 Dexamethasone is a glucocorticoid with a known reductive effect on several of these mediators and on the expression of VEGF.4Starting in 2016, infants receiving laser ablation for type 1 ROP at Skåne University Hospital were administered dexamethasone eye-drops postoperatively, us
Popular Abstract in Swedish Som ett skepp uti vilda havet, den kristna församlingen i ärkebiskop Laurentius Petris verk I 1593 års Uppsala mötes "förening om läran, ceremonier och kyrkotukt" finns följande avsnitt : Thernäst bejake och vederkännes vi oss alldeles vele holle vidh the Apostoliske, Niceniske och Athanasii symbola, såsom och vidh then äldste, rätte och oförrandrede Ausburgiske confeThe aim of this thesis is to present the ecclesiology of Laurentius Petri, a former student at Wittenberg who was archbishop of Uppsala from 1531 to his death 1573. He had a decisive role in the founding of the Church of Sweden, especially through his Swedish Church Ordinance(1571). Nevertheless most of his seventy-three writings are little known and have been rarely studied. Chapter one st
Popular Abstract in Swedish Forskningen som presenteras i denna avhandling fokuserar på tillverkning av små strukturella enheter (komponenter) samt tillämpning av ny teknologi för att adressera viktiga medicinska forskningsfrågeställningar. Framtagande av teknologi som använder sig av komponenter som är tusentals gånger mindre än bredden på ett hår är svårt men möjligt. Denna avhandling fokuserar This thesis focuses on the study of thin-film sensor technologies, novel microfabrication technologies, and thin-film technology in general. The work discusses electrochemical sensors and mechanical sensor technologies as well as fabrication strategies for them. Also included are mechano-chemical studies of the vancomycin DAla (Bacteria membrane analogue motif ) binding reaction in different chemica
Background: It is of great clinical importance to exclude myocardial infarction in patients with suspected coronary artery disease who do not have stress-induced ischemia. The diagnostic use of myocardial perfusion single-photon emission computed tomography (SPECT) in this situation is sometimes complicated by attenuation artifacts that mimic myocardial infarction. Imaging in the prone position ha
Heterogeneous patterns of genomic differentiation are commonly documented between closely related populations and there is considerable interest in identifying factors that contribute to their formation. These factors could include genomic features (e.g., areas of low recombination) that promote processes like linked selection (positive or purifying selection that affects linked neutral sites) at
Background and objectives: Progressing climate change is accompanied by a worldwide increase in the intensity, frequency, and duration of heat wave events. Research has shown that heat waves are an emerging public health problem, as they have a significant impact on mortality. As studies exploring this relationship are scarce for Latvia, this study aims to investigate the short-term associations b
INTRODUCTION: Variants in collagen-related genes COL1A1, COL3A1, COL5A1 andCOL5A2 are associated with Ehlers-Danlos syndrome (EDS), a heterogeneous groupof connective tissue disorders strongly associated with increased bleeding. Of patientswith incompletely explained bleeding diathesis, a relatively high proportion were shown to harbour at least one heterozygous variant of unknown significance (VU
The aim of this study was to determine the photon energy dependence of absorbed dose measurements, in a comparison of optically stimulated luminescence (OSL) in NaCl with thermoluminescence (TL) in LiF:Mg,Cu,P. The comparisons were made at exposure to ionizing radiation in the photon energy range 20 keV to 1.3 MeV. Specially designed dosemeter kits containing both NaCl and LiF were used under i) l
Introduction: The standard therapy for exocrine pancreatic insufficiency (EPI) is porcine-derived pancreatic enzyme replacement therapy (PERT). In the present study we tested a new approach with a mixture of pancreatic- like enzymes of microbial origin (PLEM) in a 1-week efficacy study in EPI pigs. In addition to the conventionally used coefficient of fat and nitrogen absorption (CFA and CNA), par
Objectives: Left ventricular ejection fraction (EF) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are important surrogate markers of cardiac function and wall stress. Randomized trials of heart failure (HF) have shown improvements in survival in patients with reduced EF (<40%, HFrEF) but not with preserved EF (≥50%, HFpEF) or mid-range EF (40-49%, HFmrEF). Limited information is availa
Background: The Osborn or J-wave, an upright deflection of the J-point on the electrocardiogram (ECG), is often observed during severe hypothermia. A possible relation between Osborn waves (OW) and increased risk of ventricular arrhythmia has been reported. We sought to determine whether the level of targeted temperature management (TTM) following out-of-hospital cardiac arrest (OHCA) affects the
Background: Despite the presence of efferent neural pathways from the cortex to brainstem, evidence for cognitive inhibition and sensory gating on the auditory brainstem has been mixed. Some previous studies have suggested auditory brainstem responses (ABR) can be affected by cognitive load whereas others have not. Purpose: The present study explores if the ABR recorded from adults with normal hea
The first detailed chemical abundance analysis of the M-dwarf (M4.0) exoplanet-hosting star Ross 128 is presented here, based upon near-infrared (1.5-1.7 μm), high-resolution (R ∼ 22,500) spectra from the SDSS Apache Point Galactic Evolution Experiment survey. We determined precise atmospheric parameters T eff = 3231 ±100 K, log g = 4.96 ±0.11 dex and chemical abundances of eight elements (C, O, M
Background: A varying response to cholinesterase inhibitor (ChEI) treatment has been reported among patients with Alzheimer’s disease (AD). Whether the individual-specific response directly affects time to nursing home placement (NHP) was not investigated. Objective: We examined the relationship between the 6-month response to ChEI and institutionalization. Methods: In a prospective, observational
Background: Treatment for cleft lip and/or palate (CL/P) involves a multidisciplinary team of experts who aim to improve ones’ appearance, health-related quality of life, and speech function. To appropriately measure outcomes in CL/P from the patient perspective, a CL/P-specific patient-reported outcome (PRO) instrument is needed. The CLEFT-Q is a self-report PRO instrument developed to evaluate t
Aim: This study compared follow-up protocols for paediatric celiac disease (CD) led by either paediatricians or dietitians at Swedish university hospitals. Methods: We followed 363 CD patients under 18 years at the university hospitals in Malmö (n = 140) and Lund (n = 79) between 2011 and 2013 and after they merged to become Skåne (n = 144) between 2014 and 2016. Both Lund and Malmö provided regul
