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A simple high-throughput method for automated detection of Drosophila melanogaster light-dependent behaviours

Background: Like most living organisms, the fruit fly Drosophila melanogaster exhibits strong and diverse behavioural reactions to light. Drosophila is a diurnal animal that displays both short- and long-term responses to light, important for, instance, in avoidance and light wavelength preference, regulation of eclosion, courtship, and activity, and provides an important model organism for unders

Reduced variability of endurance time in new protocols for exercise tests in COPD

Purpose: For exercise testing of COPD patients, a standard endurance test (ET) with constant workload is recommended. The test suffers from large inter-individual variability and need for large sample sizes in order to evaluate treatment effects. Methods: A new protocol for ET in COPD was designed. In contrast to the standard ET, the new ET involved an increasing workload in order to reduce the st

Population Pharmacokinetic Modelling of FE 999049, a Recombinant Human Follicle-Stimulating Hormone, in Healthy Women After Single Ascending Doses

OBJECTIVE: The purpose of this analysis was to develop a population pharmacokinetic model for a novel recombinant human follicle-stimulating hormone (FSH) (FE 999049) expressed from a human cell line of foetal retinal origin (PER.C6(®)) developed for controlled ovarian stimulation prior to assisted reproductive technologies.METHODS: Serum FSH levels were measured following a single subcutaneous FE

Global Stroke Statistics 2019

Background: Data on stroke epidemiology and availability of hospital-based stroke services around the world are important for guiding policy decisions and healthcare planning. Aims: To provide the most current incidence, mortality and case–fatality data on stroke and describe current availability of stroke units around the world by country. Methods: We searched multiple databases (based on our exi

Autonomy and Metacognition : A Healthcare Perspective

Part I of the dissertation examines the cognitive aspects of autonomy. The central question concerns what kind of cognitive capacity autonomy is. It will be argued that the concept of autonomy is best understood in terms of a metacognitive capacity of the individual. It is argued that metacognition has two components: procedural reflexivity and metarepresentation. Metarepresentation in turn can be

Development and Characterisation of a Laser-Based Hard X-Ray Source

Popular Abstract in Swedish I denna avhandling presenteras en ny typ av röntgenkälla baserad på ett laser-producerat plasma. Röntgenstrålning alstras genom att fokusera laserpulser på ett strålmål. Energin i de enskilda laserpulserna blott är cirka 150 mJ, men tack vare den extremt korta pulstiden 100 fs (10E-13 s), blir laserns toppeffekt mer än 1 TW (10E12 W). Den extremt intensiva laserstrålninA laser-produced plasma was generated by focusing 100 fs laser pulses, with an energy of 150 mJ, onto metal targets. The laser intensity was expected to reach 10E17 W/cm2. Radiation was emitted from the created plasma, with photon energies extending up to the MeV regime. The laser-based X-ray source was optimised, with the purpose of making it a realistic source of hard X-rays (>10 keV). Dedicated

Empty Names and Reference

The problem of empty names derives from the fact that empty names fail to refer. The reference failure of empty names implies that sentences containing empty names lack truth-conditions. As a consequence those sentences are meaningless, according to many theories of meaning. The present dissertation addresses the problem of empty names and proposes a solution to the problem at hand. In brief, the

Butterfly Diversity and Dispersal in Fragmented Grasslands

Popular Abstract in Swedish Under de senaste decennierna har utbredningen och förekomsten i av många arter av fåglar, växter och insekter knutna till jordbrukslandskap på olika håll i Europa minskat på grund av jordbrukets rationalisering och intensifiering. För att motverka dessa negativa trender måste man ha kännedom om den relativa betydelsen av lokala och regionala ekologiska processer för popDuring the last decades, the distribution and abundance of many European species of birds, plants and insects in agricultural landscapes have declined due to agricultural intensification. To be able to mitigate these declines, it is essential to know the relative importance on local and regional ecological processes on population persistence and patterns of species richness. I have studied the ef

Membrane Filtration for Fractionation of Biomass Compounds - Process Design for the Separation of Hemicelluloses and Lignin from Alkaline Solutions

Popular Abstract in Swedish Ny innovativ processdesign har resulterat i två processer som kan göra tillverkningen av förnyelsebara plaster och bränslen konkurrenskraftiga mot dagens fossila alternativ. Den nya designen har gjort vissa processteg upp mot 40 gånger så effektiva som med dagens teknik. Vikten av att ställa om dagens samhälle, som till stor del är beroende av fossila resurser, till eIt is important to replace fossil resources such as oil, coal and natural gas with renewable raw materials for the production of materials and fuels in order to reduce environmental impact. Furthermore, these raw materials should preferably be residues, e.g. agricultural or forest residues, in order not to compete with the production of human food and animal feed. High molecular weight arabinoxyla

Marginal Productivity Indices and Linear Programming Relaxations for Dynamic Resource Allocation in Queueing Systems

Many problems concerning resource management in modern communication systems can be simplified to queueing models under Markovian assumptions. The computation of the optimal policy is however often hindered by the curse of dimensionality especially for models that support multiple traffic or job classes. The research focus naturally turns to computationally efficient bounds and high performance he

Sveriges NATO-medlemskap - En analys av svenska identitetens förhållningssätt

In the wake of Russia’s escalation of the invasion of Ukraine in early 2022, Swedish politics seemed to suddenly change stance in regards to its participation in the military alliance Nato. Polls on the matter were seemingly flipped on their head. This paper aims to investigate how this came to pass through a constructivist lens about how a country with such deep historical, and cultural roots in

On a Network Centrality Maximization Game

We study a network formation game where n players, identified with the nodes of a directed graph to be formed, choose where to wire their outgoing links in order to maximize their PageRank centrality. Specifically, the action of every player i consists in the wiring of a predetermined number di of directed out-links, and her utility is her own PageRank centrality in the network resulting from the

ESS DTL Tuning Using Machine Learning Methods

The European Spallation Source, currently under construction in Lund, Sweden, will be the world's most powerful neutron source. It is driven by a proton linac with a current of 62.5 mA, 2.86 ms long pulses at 14 Hz. The final section of its normal-conducting front-end consists of a 39 m long drift tube linac (DTL) divided into five tanks, designed to accelerate the proton beam from 3.6 MeV to 90 M

Knowledge as a Public Good: Reconceiving the Purpose and Methods of Knowledge Production

This volume originally started as a conversation between academics from across the Arab world, all of whom have bridged their academic careers or professional development expertise to the public sphere in order to use their knowledge more actively to push for progressive, democratic change in their respective countries. Over the course of the conversation, Arab engaged scholars and activists share

Using choice experiments to assess people's preferences for railway transports of hazardous materials

This article investigates whether the choice experiment approach can be used to assess people's preferences and the determinants of these preferences in order to estimate the costs and benefits of different configurations of the transport of hazardous materials by rail. Changes in the exposure to hazardous materials that people are subjected to are used rather than changes in accident risk. To the

The Street of Associations : Migration and Infrastructural (Re)Production of Norra Grängesbergsgatan, Malmö

As global migration alters the demography of Swedish cities in the postwelfare era, socio-spatial polarisation and discrimination present acute challenges. In recent decades, Malmö has transformed from an industrial into a postindustrial, service economy-oriented city. The neoliberal urban planning and regeneration policies guiding such processes carry detrimental social and economic effects for u

The Specter of Potential Foreigners : Revisiting the Postcolonial Citizenship Regimes of Myanmar and India

Revisiting the citizenship regimes of Myanmar and India through a comparative lens, this article argues that a specter of the “potential foreigner” is decisive in the adjudication of citizenship in both countries. Citizenship is conceptualized not only on the basis of who is a citizen, but a perennial suspicion towards those who may not be. We frame this argument in the context of increasingly res