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The endothelium mediates a nitric oxide‐independent hyperpolarization and relaxation in the rat hepatic artery

The rat hepatic artery responds to acetylcholine (ACh) with an endothelium‐dependent relaxation, which is unaffected by nitric oxide (NO) synthase and cyclooxygenase inhibition. The purpose of this study was to investigate whether the NO‐independent relaxation is caused by hyperpolarization of the smooth muscle cells. In vessels with endothelium ACh induced a hyperpolarization in the presence of 0

Combined analysis of satellite and ground data for winter wheat yield forecasting

We built machine learning and image analysis tools in order to forecast winter wheat yield based on a rich multi dimensional tensor of agricultural information spanning different scales. This information consists of satellite multi-band images, local soil samples obtained from national databases, local weather as well as field data from 23 farms cultivating winter wheat in southern Sweden. This is

Transcranial direct current stimulation based on quantitative electroencephalogram combining positive psychotherapy for major depression

Abstract. Frontal cortex activity in the left hemisphere during depression is reduced. Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that can increase frontal cortex activity. Therapy based on tDCS and positive psychology (PP) therapy was applied improving patients’ quality of life. The present study compared three conditions 29 participants with clinicFrontal cortex activity in the left hemisphere during depression is reduced. Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation technique that can increase frontal cortex activity. Therapy based on tDCS and positive psychology (PP) therapy was applied improving patients’ quality of life. The present study compared three conditions participants with clinical depression

The formant dynamics of long close vowels in three varieties of Swedish

This study compares the acoustic realisation of /iː yː ʉː uː/ inthree varieties of Swedish: Central Swedish, Estonian Swedish, and Finland Swedish. Vowel tokens were extracted from isolated words produced by six elderly female speakers from each variety. Trajectories of the first three formants were modelled with discrete cosine transform (DCT) coefficients, enabling the comparison of the formant This study compares the acoustic realisation of /i: y: ʉ: u:/ in three varieties of Swedish: Central Swedish, Estonian Swedish, and Finland Swedish. Vowel tokens were extracted from isolated words produced by six elderly female speakers from each variety. Trajectories of the first three formants were modelled with discrete cosine transform (DCT) coefficients, enabling the comparison of the formant

Heterosubtypic Immunity to Influenza A Virus Infections in Mallards May Explain Existence of Multiple Virus Subtypes

Wild birds, particularly duck species, are the main reservoir of influenza A virus (IAV) in nature. However, knowledge of IAV infection dynamics in the wild bird reservoir, and the development of immune responses, are essentially absent. Importantly, a detailed understanding of how subtype diversity is generated and maintained is lacking. To address this, 18,679 samples from 7728 Mallard ducks cap

Patient doses from medical examinations in Russia: 2009–2015

The aim of this study was to evaluate adult patient doses in Russia in the context of patient protection. Effective doses from x-ray and nuclear medicine examinations were assessed using two approaches. The first was based on data collection performed by the authors in hospitals in St. Petersburg and other 17 Russian regions. The second approach was to assess mean doses through the collective dose

Early patient contact in primary care: a new challenge

Background The Medical School of Lund University, Sweden, has introduced an early patient contact course, including training in communication and examination skills. The course runs parallel with theoretical subjects during the students' first two-and-a-half years. General practitioner (GP) participation is gradually increasing, and in the last half-year of the course GPs in all health centres in

A decade of progress in understanding the structural basis of protein synthesis

The key reaction of protein synthesis, peptidyl transfer, is catalysed in all living organisms by the ribosome - an advanced and highly efficient molecular machine. During the last decade extensive X-ray crystallographic and NMR studies of the three-dimensional structure of ribosomal proteins, ribosomal RNA components and their complexes with ribosomal proteins, and of several translation factors

Inkomst av näringsfastighet i enskild näringsverksamhet - arbetsinkomst eller kapitalinkomst?

Popular Abstract in Swedish I samband med 1990 års skattereform förändrades den allmänna inkomstskatten i grunden. Bl.a. infördes skilda skatteskalor för arbetsinkomster och kapitalinkomster. Inkomster som genereras av arbete beskattas progressivt med 45-75 % men avkastning av kapital proportionellt med 30 %. Allokering av inkomst till respektive inkomstkategori har därför stor betydelse i skattesSince the tax reform of 1990 the Swedish tax system separates earned income and capital income. On earned income such as "income from business" taxes and fees leads to a total margin tax burden that vary between 45 and 75 %. This margin effect can be compared to the 30 % proportional income tax on capital income. The allocation of income to earned income or capital income is therefore an important

Enlightened Prejudices : Anti-Jewish Tropes in Modern Philosophy

In the wake of the atrocities of the twentieth century, the standard account of the Enlightenment, as a warranty of universal ideals of rationality and morality, has been challenged from a number of different angles. In line with these critical discourses, the present article investigates how, to a significant extent, two of the greatest philosophers of reason, Kant and Hegel, underpin their unive

The Estonian forest sector in transition to sustainability? : Capturing sustainability with the help of integrated assessment

This thesis has two main objectives. The first is to analyse the potential of existing assessment tools and methods to incorporate the different dimensions of sustainability in an assessment. The second is to apply some of these tools in a case study in order to determine how forest sector can better contribute to sustainable development in Estonia. The first aim is addressed in a theoretical sect

The long-term course of depressive disorders in the Lundby Study.

Background. The Lundby Study is a longitudinal cohort study on a geographically defined population consisting of 3563 subjects. Information about episodes of different disorders was collected during field investigations in 1947, 1957, 1972 and in 1997. Interviews were carried out about current health and past episodes since the last investigation; for all subjects information was also collected fr

Measurement Techniques for Respiratory Tract Deposition of Airborne Nanoparticles: A Critical Review.

Abstract Determination of the respiratory tract deposition of airborne particles is critical for risk assessment of air pollution, inhaled drug delivery, and understanding of respiratory disease. With the advent of nanotechnology, there has been an increasing interest in the measurement of pulmonary deposition of nanoparticles because of their unique properties in inhalation toxicology and medicin

Influence of order and type of drug (bisoprolol vs. enalapril) on outcome and adverse events in patients with chronic heart failure: a post hoc analysis of the CIBIS-III trial

Aims Angiotensin-converting enzyme inhibitors (ACE-Is) and beta-blockers are associated with improved outcome in patients with chronic heart failure (CHF). In this post hoc analysis of the CIBIS III trial, we examined the influence of the order of drug administration on clinical events and achieved dose. We also assessed the relations between dose levels and baseline variables or adverse events. M

Paternalism in general practice - physician's power and patient's autonomy

Popular Abstract in Swedish Paternalism i allmänläkarens vardag - om läkarens makt och patientens rätt till självbestämmande. I mitt vardagliga arbete som allmänläkare möter jag patienter med olika symtom och sjukdomar. Hur bör allmänläkaren förhålla sig till en patient som ställer krav på en åtgärd – en speciell undersökning, ett recept på en viss medicin eller ett intyg – som läkaren inte finneThe overall aim of this thesis was to identify and analyse situations raising the question of possible paternalism in everyday general practice in Sweden. Both questionnaires to a random sample of respondents and interviews have been used. The ethical awareness among GPs in Sweden and the variety of ethical issues, suggest that medical ethics is a subject of high relevance in general practice. Th

Caleacte : Production and Exchange in a North Sicilian Town c. 500 BC-500 AD

The study deals with the ancient town of Caleacte, modern Caronia, on the north coast of Sicily. Information provided by ancient textual sources, epigraphy and archaeology on the economic conditions and framework of the site and its micro-region are presented in the first chapter. Production and exchange through a diachronic perspective of nearly 1,000 years is illustrated through the study of pot

Risk and Vulnerability Analysis of Interdependent Technical Infrastructures: Addressing Socio-Technical Systems

The society of today is highly dependent on technical infrastructures. Several incidents around the world the last decades have clearly highlighted the major effects technical infrastructure breakdowns have on life, health and economy of society. The vulnerabilities inherent in our technical infrastructures must be addressed in a proactive manner; it is not feasible to wait for major incidents to

NSB 2014 - 10th Nordic Symposium on Building Physics - Full Papers

This symposium presents two tracks, one practical and one more theoretical, divided in ten topics, and presented in three parallel sessions. Two new topics are introduced; “Historical Buildings” and “Challenges for the future”. The intention of adding Historical Buildings is to gather people with different backgrounds, for example Building Physicists, Building antiquarians, Building Biologists, Ar

A knowledge process perspective on the improvement of software processes

Popular Abstract in Swedish I och med att mjukvarubaserade produkter ökar i antal ökar också vikten av en effektiv mjukvaruutvecklingsprocess, ur ett konkurrensperspektiv. Bristfällig produktkvalitet och höga utvecklingskostnader är något som mjukvaruutvecklingsorganisationer under många år har kämpat med. Studier inom SPI (software process improvement) syftar till att förbättra produktkvalitet ocThe number of software-based products is increasing, which is why the importance of an efficient software development process is also increasing, from a competitive advantage perspective. For years, software development organizations have been plagued by poor product quality and high development costs. Studies in software process improvement (SPI) have concerned themselves with improving the softw