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Population Pharmacokinetic Modelling of FE 999049, a Recombinant Human Follicle-Stimulating Hormone, in Healthy Women After Single Ascending Doses

OBJECTIVE: The purpose of this analysis was to develop a population pharmacokinetic model for a novel recombinant human follicle-stimulating hormone (FSH) (FE 999049) expressed from a human cell line of foetal retinal origin (PER.C6(®)) developed for controlled ovarian stimulation prior to assisted reproductive technologies.METHODS: Serum FSH levels were measured following a single subcutaneous FE

People, lakes and seashores : Studies from the Baltic Sea basin and adjacent areas in the early and Mid-Holocene

During the Early and Mid-Holocene significant changes in the ecology and socio-cultural spheres occurred around the Baltic Sea. Because of the underlying climatic changes and thus environmental alterations, the area was the scene for various cultural developments during the period under investigation. In the course of the melting of the glaciers at the end of the last Ice Age, isostatic and eustat

Leadership, a measurable talent

In every gathered group of people, one person will be appointed the leadership. The choice of leader will be mutual and based on that this person has the most appropriate and trained talent for leadership and is best prepared for the task. Ultimately there should be a team of leaders that support each other and co operate in the leadership, or take turns. Leadership is dependent on the human facto

Resolution among major placental mammal interordinal relationships with genome data imply that speciation influenced their earliest radiations

Background: A number of the deeper divergences in the placental mammal tree are still inconclusively resolved despite extensive phylogenomic analyses. A recent analysis of 200 kbp of protein coding sequences yielded only limited support for the relationships among Laurasiatheria (cow, dog, bat and shrew), probably because the divergences occurred only within a few million years from each other. It

The Formative Years of Anglo-Iranian Relations (1907-1953): Colonial Scramble for Iran and Its Political Legacy

As the title largely illustrates, this study seeks to investigate, from a diplomatic-history and geostrategic perspective, the key developments in Anglo-Iranian relations during what may best be dubbed their “formative years,” ranging from 1907 to 1953. Having thus provided a glimpse into pre-twentieth-century Persian–British relations, it moves to analyze the division of Persia into two spheres o

Trötta mammors försvarare : familjevärderingar i Kerstin Thorvalls bilderböcker från 1970-talet

Kerstin Thorvall (1925–2010) is a Swedish author of books for children and young adults, as well as books for adults. In 1965, she wrote the article “Do all authors of children's books live in Tomtebolandet?” (“Bor alla barnboksförfattare i Tomtebolandet”, Expressen 1965) in which she claims that gender roles in Swedish children's literature, are depicted in an old and stereotypical fashion. She a

An Architecture for Resource Bounded Agents

We study agents situated in partially observable environments, who do not have sufficient resources to create conformant (complete) plans. Instead, they create plans which are conditional and partial, execute or simulate them, and learn from experience to evaluate their quality. Our agents employ an incomplete symbolic deduction system based on Active Logic and Situation Calculus for reasoning abo

O2-binding to heme: electronic structure and spectrum of oxyheme, studied by multiconfigurational methods

We have studied the ground state of a realistic model of oxyheme with multiconfigurational second-order perturbation theory (CASPT2). Our results show that the ground-state electronic structure is strongly multiconfigurational in character. Thus, the wavefunction is a mixture of many different configurations, of which the three most important ones are approximately 1FeII–1O2 (70%), (12%) and 3FeII

Using choice experiments to assess people's preferences for railway transports of hazardous materials

This article investigates whether the choice experiment approach can be used to assess people's preferences and the determinants of these preferences in order to estimate the costs and benefits of different configurations of the transport of hazardous materials by rail. Changes in the exposure to hazardous materials that people are subjected to are used rather than changes in accident risk. To the

Electroanalytical study of Prussian Blue modified glassy carbon paste electrodes

Two types of glassy carbon (GC) powder (i.e., Sigradur K and Sigradur G) have been mixed with mineral oil to obtain glassy carbon paste electrodes (GCPE's). The electrochemical behavior of such electrodes at different percentages of glassy carbon has been evaluated with respect to the electrochemistry of ferricyanide as revealed with cyclic voltammetry and the best paste composition was chosen. GC

High performance MRI simulations of motion on multi-GPU systems

Background: MRI physics simulators have been developed in the past for optimizing imaging protocols and for training purposes. However, these simulators have only addressed motion within a limited scope. The purpose of this study was the incorporation of realistic motion, such as cardiac motion, respiratory motion and flow, within MRI simulations in a high performance multi-GPU environment. Method

Comparison of three different techniques for application of water solutions to Finn Chambers®.

BACKGROUND: With regard to contact allergy, the dose of a sensitizer per unit skin area is an important factor for both sensitization and elicitation, and therefore a known amount/volume of test preparation should be applied at patch testing. OBJECTIVES: To compare three different techniques for the application of aqueous solutions to Finn Chambers, in order to determine the precision and accuracy

Regional innovation Policy Beyond 'Best practice': Lessons from Sweden

This paper deals with policy measures in the regional innovation system of Scania, Southern Sweden. Focus is on the innovation policy requirements of actors representing industries that draw on different knowledge bases. Previous studies have identified profound industry-specific differences concerning the organisation of knowledge sourcing between firms and other actors. In correspondence with th

Development and Modernity in Hofstede's Culture's Consequences: A Postcolonial Reading

Along with an increasingly globalized business environment and a strongly held corporate belief that the world can be rationally managed, the last two decades have witnessed a growing demand for normative models dealing with cross-cultural management issues. This trend has allowed cross-cultural management to establish itself as a significant research field, with much of the initial inspiration co

Butterfly Diversity and Dispersal in Fragmented Grasslands

Popular Abstract in Swedish Under de senaste decennierna har utbredningen och förekomsten i av många arter av fåglar, växter och insekter knutna till jordbrukslandskap på olika håll i Europa minskat på grund av jordbrukets rationalisering och intensifiering. För att motverka dessa negativa trender måste man ha kännedom om den relativa betydelsen av lokala och regionala ekologiska processer för popDuring the last decades, the distribution and abundance of many European species of birds, plants and insects in agricultural landscapes have declined due to agricultural intensification. To be able to mitigate these declines, it is essential to know the relative importance on local and regional ecological processes on population persistence and patterns of species richness. I have studied the ef

Analysis of Fire Scenarios in Order to Ascertain an Acceptable Safety Level in Multi-Functional Buildings

The construction of multifunctional buildings has increased over the last years as well as the threat level considering antagonistic events. This presents challenges for the fire safety in these types of buildings since the protection objectives needs to be more focused on the functions the buildings are providing. Further the antagonistic exposures might present more challenging fire scenarios. A

Membrane Filtration for Fractionation of Biomass Compounds - Process Design for the Separation of Hemicelluloses and Lignin from Alkaline Solutions

Popular Abstract in Swedish Ny innovativ processdesign har resulterat i två processer som kan göra tillverkningen av förnyelsebara plaster och bränslen konkurrenskraftiga mot dagens fossila alternativ. Den nya designen har gjort vissa processteg upp mot 40 gånger så effektiva som med dagens teknik. Vikten av att ställa om dagens samhälle, som till stor del är beroende av fossila resurser, till eIt is important to replace fossil resources such as oil, coal and natural gas with renewable raw materials for the production of materials and fuels in order to reduce environmental impact. Furthermore, these raw materials should preferably be residues, e.g. agricultural or forest residues, in order not to compete with the production of human food and animal feed. High molecular weight arabinoxyla

Marginal Productivity Indices and Linear Programming Relaxations for Dynamic Resource Allocation in Queueing Systems

Many problems concerning resource management in modern communication systems can be simplified to queueing models under Markovian assumptions. The computation of the optimal policy is however often hindered by the curse of dimensionality especially for models that support multiple traffic or job classes. The research focus naturally turns to computationally efficient bounds and high performance he

Guidelines-systematic-fire-safety-management

REGULATORY DOCUMENT COVER PAGE Lund University Guidelines for Systematic Fire Safety Management Type of regulatory document: Guidelines Definition of the type of regulatory document: Guidelines establish how someone must or should act in the area covered by the guidelines. A “must” rule is to be complied with, whereas the nature of a “should” rule is more of a strong recommendation, which means th

https://www.staff.lu.se/sites/staff.lu.se/files/2026-01/guidelines-systematic-fire-safety-management.pdf - 2026-05-10