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Standardization and Utilization of Biobank Resources in Clinical Protein Sciene with Examples of Emerging Applications

Biobanks are a major resource to access and measure biological constituents that can be used to monitor the status of health and disease, both in unique individual samples and within populations. Most “omic” activities rely on access to these collections of stored samples to provide the basis for establishing the ranges and frequencies of expression. Furthermore, information about the relative abu

Greenhouse gases from wastewater treatment - A review of modelling tools.

Nitrous oxide, carbon dioxide and methane are greenhouse gases (GHG) emitted from wastewater treatment that contribute to its carbon footprint. As a result of the increasing awareness of GHG emissions from wastewater treatment plants (WWTPs), new modelling, design, and operational tools have been developed to address and reduce GHG emissions at the plant-wide scale and beyond. This paper reviews t

High coloration performance of electrochromic devices assembled with electrolytes based on a branched boronate ester polymer and lithium perchlorate salt

An amorphous, colorless, and highly transparent polymer containing boron atoms in its branched chain architecture was synthesised from boron trioxide, poly(ethylene glycol) (PEG) and methoxy end-capped PEG. Electrolytes based on this polymer and different concentrations of lithium perchlorate (LiClO4) were prepared and characterised by impedance spectroscopy, calorimetry and thermogravimetry. The

Interaction of recombinant human cystatin C with the cysteine proteinases papain and actinidin

The interaction between recombinant human cystatin C and the cysteine proteinases papain and actinidin was studied by spectroscopic, kinetic and equilibrium methods. The absorption, near-u.v.c.d. and fluorescence-emission difference spectra for the cystatin C-proteinase interactions were all found to be similar to the corresponding spectra for chicken cystatin. The kinetics of binding of cystatin

A model for through-drying of tissue paper at constant pressure drop and high drying intensity

A mathematical model for through drying of paper at constant pressure drop was developed. The model is based on physical properties; hence, basis weight, pressure drop, drying air temperature, pore size distribution, initial gas fraction, and tortuosity are important input parameters to the model. The model was solved for different combinations of the variables basis weight, drying air temperature

Gene expression profilers and conventional clinical markers to predict distant recurrences for premenopausal breast cancer patients after adjuvant chemotherapy.

A large proportion of breast cancer patients are treated with adjuvant chemotherapy after the primary operation, but some will recur in spite of this treatment. In order to achieve an improved and more individualised therapy, our knowledge in mechanisms for drug resistance needs to be increased. We have investigated to what extent cDNA microarray measurements could distinguish the likelihood of re

Inverse modelling of thermal conductivity from temperature measurements at the Prototype Repository, Aspo HRL

The Prototype Repository, at the Aspo HRL (Hard Rock Laboratory), is a demonstration project for the deposition of spent nuclear fuel, and provides a full-scale reference for testing predictive models relating to a spent nuclear fuel repository, both its individual components as well as the complete system. The final layout involves six deposition holes, four in an inner section and two in an oute

The Power to do Good : Post-Revolution, NGO Society, and the Emergence of NGO-Elites in Contemporary Nicaragua

This thesis critically examines the world of NGOs in contemporary Nicaragua, and suggests connections between the current development 'boom' and the emergence of a materially privileged local development elite, which by means of its cultural and economic capital are in a position to exiercise considerable power in relation to other less powerful strata of the population. It is based on fieldwork c

The Evolution of Highly Variable Immunity Genes Across a Passerine Bird Radiation

In order to survive, individuals must be able to recognise and eliminate pathogens. The genes of the Major Histocompatibility Complex (MHC) play an essential role in this process in vertebrates as their diversity affects the repertoire of pathogens that can be recognised by the immune system. Emerging evidence suggests that birds within the parvorder Passerida possess an exceptionally high number

Images of memory: Depictions of the amnesiac flashback, exemplified by The Bourne Identity x 3

In old mnemonic systems, like the Memory Palaces (Ricci) and the Memory Circles (Llull), the general purpose is to organize and preserve the images of memory over time. However, in contemporary discussions of memory taking place within the field of trauma studies (Leys, Laub, Feldman, Caruth, van der Kolk), the focus is on the forgotten, and on understanding why we do not remember traumatic events

The World is a Prison to Believers : Naming and Worlds in Malcolm X

In this paper, we look at the terrain of Malcolm X's "failed rhetoric" as producing an apocalyptic refusal of world, and world making. This refusal finds its intensity from a distinct gnostic calculus, driving Malcolm X's political theology of names and worlds, seen in his oratory from the years 1962–1964. First, Malcolm X's nominal history is discussed in relation to the violence of naming and po

New Ar-40/Ar-39 alunite ages from the Colquijirca district, Peru: evidence of a long period of magmatic SO2 degassing during formation of epithermal Au-Ag and Cordilleran polymetallic ores

We present Ar-40/Ar-39 data acquired by infra-red (CO2) laser step-heating of alunite crystals from the large Miocene Colquijirca district in central Peru. Combined with previously published data, our results show that a long (at least 1.3 My) and complex period of magmatic-hydrothermal activity associated with epithermal Au-(Ag) mineralization and base metal, Cordilleran ores took place at Colqui

The effect of high post-mortem temperature on the development of pale, soft and exudative pork : Interaction with ultimate pH

The effects of post-mortem temperature and ultimate pH (pHu, 24 h post mortem) on the development of the pale, soft and exudative (PSE) characteristics in pig longissimus dorsi muscle were studied. Ten out of the 13 pigs used received pre-slaughter injections of adrenaline in order to deplete muscle glycogen stores. The two muscles from each pig were held at 12 or 35°C during rigor mortis developm

Det retrospektivt upplevda värdet av den gymnasiala spetsutbildningen : En uppföljning av unga vuxnas erfarenheter omkring ett och ett halvt år efter deras examen

Skolverket inledde på uppdrag av Regeringen hösten 2009 försöksverksamhet med riksrekryterande gymnasial spetsutbildning inom matematik, naturvetenskapliga, samhällsvetenskapliga och humanistiska ämnen. Försöksverksamheten har kontinuerligt följts upp och kontinuerligt utvärderats sedan dess. Våren 2012 tog de första eleverna inom de nio först startade utbildningarna sin examen. Syftet med delutvä

Survey of non-resuscitation fluids administered during septic shock : a multicenter prospective observational study

BACKGROUND: The indication, composition and timing of administration of non-resuscitation fluid in septic shock have so far received little attention and accordingly the potential to reduce this source of fluid is unknown. The objective of the study was to quantify and characterize non-resuscitation fluid administered to patients with septic shock.METHODS: This prospective observational study was

”Med coleurt omslag” : färgade, dekorerade och tryckta omslag på svensk bokmarknad 1787-1846. En bokhistoria.

Popular Abstract in Swedish Nuförtiden är det tryckta bokomslaget en självklar del av boken som produkt och konsumentvara. I avhandlingen studeras etableringen av bokomslaget och dess betydelse för omstruktureringen av bokmarknaden i Sverige decennierna kring 1800. Från mitten av 1700-talet blev den färdigbundna boken en betydelsefull del av bokhandelns utbud. Förlag och bokhandel började sälja deThe aim of the dissertation is to examine the significance of the paperbound book on the book market as part of the history of consumption. It is an examination of the materiality of the book, in which the form and function, economics and distribution of the binding during the last century of the hand-press era are studied. The intention has been to show that the ready-bound book was a means for t

C4b-binding protein: The good, the bad and the deadly. Novel functions of an old friend.

C4b-binding protein (C4BP) is best known as a potent soluble inhibitor of the classical and lectin pathways of the complement system. This large 500kDa multimeric plasma glycoprotein is expressed mainly in the liver but also in lung and pancreas. It consists of several identical 75kDa α-chains and often also one 40kDa β-chain, both of which are mainly composed of complement control protein (CCP) d

Transition from HCCI to PPC : Investigation of Fuel Distribution by Planar Laser Induced Fluorescence (PLIF)

In a previous study, in order to investigate the effect of charge stratification on combustion behavior such as combustion efficiency and combustion phasing which also largely affects the emissions, an experiment was conducted in a heavy-duty compression ignition (CI) metal engine. The engine behavior and emission characteristics were studied in the transition from HCCI mode to PPC mode by varying

TIA in the Swedish Stroke Register (Riksstroke). Aspects on diagnostic validation, risk factors, investigations, and therapies

Background: Transient ischemic attacks (TIA) indicate an increased risk of stroke, one of the leading causes of death and disability worldwide. In order to prevent stroke, our knowledge of diagnosis, demographics, risk factors, investigations, and treatment of patients with TIA needs to be improved.Aims: The aims of this thesis were to validate data and diagnoses in the Riksstroke TIA module (Riks