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Purpose: Octreotide SC depot is a novel, ready-to-use formulation administered via a thin needle. In a phase 1 study in healthy volunteers, this formulation provided higher bioavailability of octreotide with faster onset and stronger suppression of IGF-1 in healthy volunteers versus long-acting intramuscular (IM) octreotide. This phase 2 study evaluated the pharmacokinetics, efficacy, and safety o

Background: TMEM199 deficiency was recently shown in four patients to cause liver disease with steatosis, elevated serum transaminases, cholesterol and alkaline phosphatase and abnormal protein glycosylation. There is no information on the long-term outcome in this disorder. Results: We here present three novel patients with TMEM199-CDG. All three patients carried the same set of mutations (c.13-1

Biorefineries are rapid growing branches in the world of sustainable chemical engineering, and one aspect that becomes more and more important is the reuse and valorization of different by-products. In sugar mills, molasses is a low value by-product mainly used for animal feed. However, a large part of the molasses contains the main product of the sugar mill: sucrose. By using membrane filtration,

Shaken baby syndrome has typically been associated with findings of subdural haematoma, retinal haemorrhages and encephalopathy, which are referred to as the triad. During the last decade, however, the certainty with which the triad can indicate that an infant has been violently shaken has been increasingly questioned. The aim of this study was to determine the diagnostic accuracy of the triad in

More than 50 irregular satellites revolve around Jupiter and more than 30 around Saturn. There, at least three collisional families were identified. Among these, the Himalia family of prograde irregular moons at Jupiter is characterised by a velocity dispersion of several hundred m/s, inconsistent with a collisional origin (Nesvorný et al., 2003). Here we investigate whether the dispersion could s

Background: Patients experiencing high levels of pain after surgery remains a considerable clinical problem. Often, no consensus about the best analgesic treatment is present. The majority of clinical trials regarding postoperative pain, generally, target the average analgesic efficacy. In terms to step forward, a focus on the individual patients´ pain levels is needed and an identification of the

Detta är den sjätte årsrapporten från Svensk Dagfjärilsövervakning, ett nationelltmiljöövervakningsprogram som koordineras av Lunds universitet på uppdrag avNaturvårdsverket sedan 2010. Svensk Dagfjärilsövervakning är ett samarbete mellan Sveriges Entomologiska Förening, Naturvårdsverket, Lunds universitet, Sveriges lantbruksuniversitet och Länsstyrelserna. Verksamheten möjliggörs av frivilliga laThis is the sixth annual report of the Swedish Butterfly Monitoring Scheme, a national monitoring programme coordinated by Lund University for the Swedish Environmental Protection Agency since 2010. The programme is a partnership between the Entomological Society of Sweden, the Swedish Environmental Protection Agency, Lund University, the Swedish University of Agricultural Sciences and the Swedish

This report presents the sixth version of the European Grassland Butterfly Indicator, one of the EU biodiversity indicators of the European Environment Agency.The indicator is based on more than 9200 transects in national Butterfly Monitoring Schemes covering 22 countries across Europe, most of them active in the European Union. In 2015, counts were made in more than 4500 transects.Butterflies rep

Cardiovascular diseases (CVDs) remain a leading cause of death globally. According to the American Heart Association, approximately 19.1 million deaths were attributed to CVDs in 2020, in particular, ischemic heart disease and stroke. Several known risk factors for CVDs include smoking, alcohol consumption, lack of regular physical activity, and diabetes. The last decade has been characterized by

The recent randomized controlled phase III CLEAR trial results are the last to complement immune checkpoint inhibitor (ICI)-based doublet combination therapies for treatment-naïve metastatic clear-cell renal cell carcinoma. The CLEAR trial demonstrated an improved progression-free survival (PFS), overall survival (OS), and an objective response rate (ORR) benefit for the combination of lenvatinib

Context: End-stage kidney disease (ESKD) is characterized by high physical and psychological burden, and therefore, more knowledge about the palliative care provided close to death is needed. Objectives: To describe symptom prevalence, relief, and management during the last week of life, as well as end-of-life communication, in patients with ESKD. Methods: This study was based on data from the Swe

We present evidence of a submerged early Holocene landscape off the Blekinge coastline in the Baltic Sea, dating to the Yoldia Sea and Initial Littorina Sea Stages when the water level was lower than at present. 14C dated wood remains obtained by surveillance diving and new archaeological findings in combination with bathymetric analyses and interpolations between other sites across the Baltic Sea

Introduction: The use of pharmacokinetic assessment for optimal prophylactic dosing of factor concentrates in haemophilia has gained increasing enthusiasm over the last decade. However, blood sampling on several occasions is burdensome and limited sampling using population-based PK is appealing. Aim: To compare the pharmacokinetics and dosing recommendations for prophylaxis using six-point single

Automotive brake rotors are commonly made from gray cast iron (GCI). During usage, brake rotors are gradually worn off and periodically replaced. Currently, replaced brake rotors are mostly remelted to produce brand-new cast iron products, resulting in a relatively high energy consumption and carbon footprint into the environment. In addition, automotive brakes emit airborne particles. Some of the

Molecular signatures to guide decisions for adjuvant chemotherapy are recommended in early ER-positive, HER2-negative breast cancer. The objective of this study was to assess what impact gene-expression-based risk testing has had following its recommendation by Swedish national guidelines. Postmenopausal women with ER-positive, HER2-negative and node negative breast cancer at intermediate clinical

REGULATORY DOCUMENT COVER PAGE Lund University Guidelines for Evacuation Exercises Type of regulatory document: Guidelines Definition of the type of regulatory document: Guidelines establish how someone must or should act in the area covered by the guidelines. A “must” rule is to be complied with, whereas the nature of a “should” rule is more of a strong recommendation, which means that in excepti

https://www.staff.lu.se/sites/staff.lu.se/files/2026-01/guidelines-evacuation-exercises.pdf - 2026-05-16

Novisch 2017 Logoped- och Audiologiutbildningen Hej blivande logoped- eller audiologistudent! Stort grattis till att DU har blivit antagen till logoped- eller audionomprogrammet vid Lunds Universitet! Utbildningarna börjar traditionsenligt med två fartfyllda veckor tillsammans med dina nya klasskamrater och oss faddrar. Denna period (och mer därtill...) kallas för NOVISCHPERIODEN. Vi är ett gäng g

https://www.student.med.lu.se/sites/student.med.lu.se/files/rymdigtnovisch-hafte.pdf - 2026-05-16