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Methods to explore reactions of sialic acid derivatives

Att ta reda på hur och varför reaktioner sker molekyler emellan är ingen lätt uppgift. Ingen kamera är tillräckligt liten eller känslig (än) för att filma det som händer på molekylnivå. Istället behöver forskare genomföra experiment och samla stora mängder data för att få en bild av hur en reaktion går till, den så kallade reaktionsmekanismen. Att ta reda på reaktionsmekansimer ökar förståelsen föN-Acetylneuraminic acid (Neu5Ac) is the most common form of sialic acid, a nine-carbon sugar often situated at the ends of glycoconjugates. Its unique reactivity makes it a complex substrate to work on, but new methods are continuously developed. In 2007, Ye et.al. reported a regioselective substitution by morpholine on position 4 of fully acetylated Neu5Ac, with retained stereochemistry. The anom

Rymmer straffsystemet en ny kriminalisering? – En analys av godtagbarheten av en nykriminalisering av rymning från fängelse

Förevarande uppsats syftar till att analysera godtagbarheten av en kriminali-sering av rymning från fängelse i svensk rätt. I den större delen av uppsatsen analyseras godtagbarheten utifrån de fem kriterier som satts upp i SOU 2013:38 Vad bör straffas? (Straffrättsutredningen). Därefter diskuteras huruvida det finns andra överväganden som behöver göras innan en eventuell kriminalisering beslutas. This essay aims to analyse the acceptability of a criminalisation of prison es-cape in Swedish law, based on the five criteria set out in SOU 2013:38 Vad bör straffas? (What should be punished?), called Straffrättsutredningen (The Criminal Justice Investigation). Furthermore, I discuss whether other consid-erations are needed before a criminalisation is decided. The discussions are based on the te

Optimization of Exhaust Port and Valves for Heavy duty engines

The efficiency of combustion engines is crucial for their future development, prompting researchers to explore various factors to enhance performance. Among these factors, exhaust gases hold significant potential. Typically, exhaust gases carry about 30-40% of the engine's energy, which often remains underutilized. Although technologies like turbochargers have made progress in recovering some

Utgör en globalt högre havsnivå ett hot mot pågående miljöfarlig verksamhet? – En undersökning av hur tillståndspliktiga verksamheter i Skåne påverkas av stigande havsnivåer till följd av ett varmare klimat

Climate change has become a societal issue that has gained increasing attention in recent years. The Intergovernmental Panel on Climate Change, IPCC, presented in year 2007 its Fourth Assessment Report, pointing out different scenarios about the future climate, including the anticipated sea level rises during this century. More recent climate research has shown that sea levels are most likely to r

Gruppundantagsförordning nr 772/2004 för avtal om tekniköverföring

Konkurrensrätt och immaterialrätt har länge betraktats vara rättsområden som skyddar motstående intressen. En av de regleringar som finns för att underlätta förhållandet mellan de två rättsområdena är kommissionens förordning nr 772/2004 för grupper av avtal om tekniköverföring. Genom denna förordning önskar kommissionen garantera en effektiv konkurrens på marknaden samt erbjuda företag som ingår Competition Law and Intellectual Property Law are sometimes considered as areas of law which protect conflicting interests. One of the regulations striving to facilitate the relationship between these two areas is Regulation 772/2004, on the application of article 101.1 TFEU to categories of technology transfer agreements. The objectives of this Regulation are to ensure effective competition and t

Lagerstyrning av inköpsartiklar på FSL – Dimensionering av säkerhetslager utifrån given servicenivå

Background Frigoscandia Logistics AB, FSL, was founded in 1997 as a Fourth Party Logistics provider, 4PL, with the purpose to supply temperature-controlled food and other goods to customers world wide. The main purpose is to provide a complete logistics service package including physical, administrative as well as financial flows. Moreover FSL takes the ownership of the products, which is unique.

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At the End of the World Newsletter – 15 December 2024 This is the eighth newsletter for the At the End of the World research program, housed at Lund University. It is the final newsletter from our second year of activity. If you’re receiving this email, it’s because you’ve subscribed to our mailing list. Below, we’ll fill you in on some upcoming events for the spring of 2025, and also what we've b

https://www.endoftheworld.lu.se/at-the-end-of-the-world-newsletter-15-december-2024/ - 2026-05-21

Brevmall

Brevmall Kursplan i utbildning på forskarnivå 1. Identifikation och grundläggande uppgifter 1. Kurskod HAA001F 2. Kursens namn Material, materialvetenskap och materialitet: Nya perspektiv från naturvetenskap och humaniora (Materials, materials science, and materiality: New perspectives from across the natural sciences and humanities) 3. Högskolepoäng 7.5 hp 4. Beslutsuppgifter Fastställd 2022-10-2

https://www.ht.lu.se/fileadmin/user_upload/ht/filserver/doktorand/forskarutbildningsplaner/Material__materialvetenskap_och_materialitet.pdf - 2026-05-21

Rörlig hyressättning för lokaler - Särskilt om index-baserade hyresklausuler

Huvudregeln för bestämmandet av hyran i svensk rätt är att hyran ska vara till beloppet bestämd av parterna i avtalet. Bestämmelsen återfinns i 12 kap. 19 § Jordabalken (1970:994). Som undantag till detta kan hyran för lokal antingen bestämmas genom en omsättningsklausul, genom klausuler för el, värme och vatten eller genom annan beräkningsgrund. Vid avtal som strider mot paragrafen framgår enligtThe main rule for determining the rent in Swedish rental law is that the rent shall be for the amount determined. The provision is found in the 12 chapter 19 § Jordabalken (1970: 994). As exceptions, the rent for a local can either be determined by a turnover clause, by electricity, heat and water clauses or by other calculation basis. In the event of an agreement that goes against the paragraph,

Lucat administrators

The information on this page is aimed at Lucat administrators at Lund University. You will find information regarding how your work affects LUCRIS. Your work in Lucat is importantSince LUCRIS imports parts of its basic data from Lucat, it is you as the Lucat administrator who lays the foundation for LUCRIS. All employees, organisations, and affiliations (connections between people and different or

https://www.staff.lu.se/research-and-education/research-support/lucris/administer-lucris/lucat-administrators - 2026-05-21

Connecting Cities, Nature and Innovation

Providing tools, knowledge and contacts to practitioners The new buzzword, nature-based solutions (NBS), is a study area focusing on how to work with rather than against nature when imagining, designing, and rebuilding cities. The IIIEE belongs to a joint academic venture that offers commissioned courses on innovation and sustainable governance for practitioners from economies in transition with t

https://www.iiiee.lu.se/communication/impact-stories/connecting-cities-nature-and-innovation - 2026-05-21

Biomimetic Macroporous Hydrogels: Protein Ligand Distribution and Cell Response to the Ligand Architecture in the Scaffold

Macroporous hydrogels (MHs), cryogels, are a new type of biomaterials for tissue engineering that can be produced from any natural or synthetic polymer that forms a gel. Synthetic MHs are rendered bioactive by surface or bulk modifications with extracellular matrix components. In this study, cell response to the architecture of protein ligands, bovine type-I collagen (CG) and human fibrinogen (Fg)

Dry deposition of reactive nitrogen to European ecosystems: a comparison of inferential models across the NitroEurope network

Inferential models have long been used to determine pollutant dry deposition to ecosystems from measurements of air concentrations and as part of national and regional atmospheric chemistry and transport models, and yet models still suffer very large uncertainties. An inferential network of 55 sites throughout Europe for atmospheric reactive nitrogen (N-r) was established in 2007, providing ambien

NTCP modelling of lung toxicity after SBRT comparing the universal survival curve and the linear quadratic model for fractionation correction

Background. In SBRT of lung tumours no established relationship between dose-volume parameters and the incidence of lung toxicity is found. The aim of this study is to compare the LQ model and the universal survival curve (USC) to calculate biologically equivalent doses in SBRT to see if this will improve knowledge on this relationship. Material and methods. Toxicity data on radiation pneumonitis

Gates and Gods. Cults in the City Gates of Iron Age Palestine. An Investigation of the Archaeological and Biblical Sources.

The present study deals with the question of cult locales in city gate contexts in Iron Age Palestine. Both archaeological and biblical sources are analysed in order to determine the presence of gate cult locales and indicate some directions of interpretation. A general framework for the archaeological identification of cult (as proposed by Colin Renfrew and others) is discussed and applied within

The Missing Piece Defining the Crime of Aggression

The historical development of responsibility for wars and aggressive acts has seen a shift of focus during the last century. Where the attention was previously focused on the unlawfulness of a State act (the Act of Aggression), the attention is now on the involvement and responsibility of individuals. The topic of this thesis is to follow the development of the possibility to hold those behind Sta

Intracellular signaling and cellular plasticity in a rat model of L-DOPA-induced dyskinesia

Popular Abstract in Swedish Parkinsons sjukdom beror på att de dopamin-producerande cellerna i hjärnan dör. Detta leder till minskad rörlighet, svårigheter i att påbörja och avsluta en rörelse, balanssvårigheter och darrningar (tremor) hos de drabbade patienterna. Varför dopamincellerna dör är oklart och i nulägat kan man inte bota Parkinsons sjukdom, men man kan lindra symptomen med mediciner. PaParkinson's disease (PD) is a neurodegenerative disorder where the midbrain dopaminergic neurons are lost. Presently there is no cure for PD, and the most common treatment is to replace the lost dopamine pharmacologically by administration of the dopamine precursor L-DOPA. This works very well during the initial treatment period, but unfortunately a majority of the patients develop abnormal involu

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Rome in Sweden? The Catholic Offensive in Ecumenical-National Context Since World War II, ecumenical principles have been used as historical measures. This has led to re-interpretations of historical events and to alterations of sources, for example the letters and diaries by Elisabeth Hesselblad, the renewer of St. Birgitta’s order. In the literature on the Swedish Archbishop Nathan Söderblom, th

Endovascular repair of descending thoracic aortic aneurysms: an early experience with intermediate-term follow-up

PURPOSE: The purpose of this study was to report an initial experience with the endovascular repair of descending thoracic aortic aneurysm. Complications and intermediate-term morphologic changes were identified with the intent of altering patient selection and device design. METHODS: Endografts were placed into 25 patients at high-risk for conventional surgical repair over a 3(1/2)-year period. D

Manager and Civil Servant: Exploring actors' taken-for-granted assumptions in public administration

Manager och Civil Servant är en utforskning av aktörers förgivet tagna antaganden vilka styr uppfattningar kring hur offentlig förvaltning ska ske i samtida välfärdsstater. Det hävdas att mer än 30 år av pågående och riktade reformer gentemot den offentliga förvaltningen har orsakat dilemman att uppstå. Dessa dilemman har resulterat i en förskjutning av balansen kring några fundamentala pelare inoManager and Civil Servant is an exploration of actors’ taken-for-granted assumptions that govern perceptions concerning how public administration should be undertaken within contemporary welfare states. It is argued that more than 30 years of continuous reforms directed towards public administration have caused dilemmas to arise. These dilemmas have resulted in a shifting of balances regarding the