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Topiramate is biochemically classified as a fructopyranose sulphamate. Discovered as early as 1979, during middle 1980's it was approved in many countries for the treatment of epilepsies and migraine prevention. More recently, in the experimental stage, possible new indications have been disclosed: treatment of obesity, bipolar disorder, also cessation of smoking, neuropathic pain, cerebral pseudo
Phosphodiesterase type 3B (PDE3B) has been shown to be activated and phosphorylated in response to insulin and hormones that increase cAMP. In order to study serine/threonine protein phosphatases involved in the regulation of rat adipocyte PDE3B, we investigated the phosphorylation and activation of PDE3B in vivo in response to phosphatase inhibitors and the dephosphorylation and deactivation of P
Superporous agarose beads contain two sets of pores, diffusion pores and so-called superpores or flow pores, in which the chromatographic flow can transport substances to the interior of each individual bead [Gustavsson and Larsson, J. Chromatogr. A 734 (1996) 231]. The existence of pore flow may be proven indirectly by the chromatographic performance of beads but it has never been directly demons
Secondary metabolites produced by fungi and bacteria are among the potential agents that contribute to adverse health effects observed in occupants of buildings affected by moisture damage, dampness and associated microbial growth. However, few attempts have been made to assess the occurrence of these compounds in relation to moisture damage and dampness in buildings. This study conducted in the c
BACKGROUND AND AIMS: Leukocyte recruitment is a key feature in ischemia-reperfusion (I/R)-induced tissue injury. The aim of the present study was to investigate the effect of Rho-kinase inhibition on I/R-provoked leukocyte recruitment in the colon. METHODS: C57BL/6 mice were subjected to 30 min of ischemia by clamping of the superior mesenteric artery followed by 120 min of reperfusion. Intraperit
Microsoft Word - ETNB07 Ht17.docx 1 Litteraturlista, HT 2017 ETNB07: Våld, genus och kultur (15 hp) Institutionen för kulturvetenskaper Avdelningen för etnologi Godkänd av kursplanegruppen, 2017.06.07 Obligatorisk litteratur Delkurs 1: Våldets kön Connell, R.W. 2000. “Arms and the man. Using the new research on masculinity to understand violence and promoting peace in the contemporary world”. Brei
https://www.kultur.lu.se/media/utbildning/dokument/kurser/ETNB07/20172/ETNB07_Ht17.pdf - 2026-05-14
Objective The aim of this study was to estimate the rate of fetal loss in dichorionic (DC) and monochorionic (MC) twin pregnancies stratified according to zygosity and method of conception. Methods In a prospective multicenter observational study women with a twin pregnancy bad an ultrasound scan before 14 + 6 weeks' gestation in order to determine chorionicity. The fetal loss rate, the perinatal,
Popular Abstract in Swedish Normal hjärnaktivitet är beroende på en delikat balans mellan inhibitorisk och excitatorisk nervcellssignallering. Om denna balans störs och lutar mer åt en ökad excitering uppstår epileptiska anfall. Ungefär 1 % av befolkningen i västvärldens drabbas av epilepsi, framförallt av temporallobs-epilepsi (TLE) vilket är den vanligast förekommande formen av epilepsi bland vuTemporal lobe epilepsy (TLE) is the most common form of epilepsy among adult patients, and the most problematic one as seizures cannot be controlled by currently available drugs in 30 % of patients. Gene therapy based on overexpression of endogenous anti-epileptic agents such as the neuropeptide galanin and the glial cell line-derived neurotrophic factor (GDNF) represents a promising new approach
Cathepsin B is suggested to be involved in amyloid-beta (A beta) processing and Alzheimer's disease (AD). Studies of cathepsin B levels in plasma and cerebrospinal fluid (CSF) have not been previously performed. We examined cathepsin B levels in plasma and CSF samples in persons with AD, mild cognitive impairment (MCI), and healthy controls in order to test the hypothesis that cathepsin B levels c
OBJECTIVE: The aim of this study was to explore the associations between inadequate glycemic control of diabetes and psychological, anthropometric and life style variables in a population based cohort of type 1 diabetes patients. DESIGN: Cross-sectional study. METHODS: In this study 292 patients with type 1 diabetes participated, age 18-59 years. Psychological data were assessed by self-report ins
Interaction of mono- and disaccharides, polysaccharide particles and yeast cells with boronate-containing copolymers (BCC) of N-acryloyl-m-aminophenylboronic acid (NAAPBA) with NN-dimethylacrylamide (DMAA) or N-isopropylacrylamide (NIPAM) was studied. The binding of saccharides to BCC of NIPAM resulted in a shift of its phase transition temperature (Delta T-p), which provided a quantitative measur
Enzymatic hydrolysis is an agro-processing aid that can be utilized in order to improve nutritional quality of protein extracts from many sources. In this study, protein extracts from ungerminated and/or germinated local Egyptian soybean and lupin flours were hydrolyzed using the enzyme papain. The hydrolysis processes were carried out for 2 h and aliquots were withdrawn at different time interval
Klipp och klistra 1. Course Details 1. Course code ENG M13 2. Course title English: Linguistic Variation in English 3. Cycle (1st, 2nd or 3rd) 2nd 4. Higher education credits 7.5 5. Details of approval of course Syllabus approved by the Syllabus Committee of the Faculty of the Humanities and Theology 9 th April 2008. 6. Details of changes approved 2. General Information 1. Field(s) (if applicable)
https://www.sol.lu.se/media/utbildning/dokument/kursplaner/ENGM13_eng.pdf - 2026-05-14
A pre-requisite to reach the EU 2030 and beyond targets is a significantly increased ambition among property owners regarding energy-efficient refurbishments. The Swedish Energy Agency and the National Board of Housing, Building and Planning are on the Swedish government assignment developing a strategy with policy instruments to increase energy-efficiency oriented renovation. In order to design t
BACKGROUND: The locoregional failure rate remains high in advanced cervical carcinoma. Chemotherapy (CT) was added to radiotherapy (RT) in order to increase disease control and to improve 5-year survival.METHODS: CT + RT included cisplatin administered 100mg/m2, d.1 plus 5-fluorouracil 1000 mg/m2 D.1 to 5, ci (120 hrs), q every 3rd week for 3 cycles, followed by RT. RT included external beam irrad
In the age of museomics, the ability to sequence the genetic material from old museum specimens provides an invaluable and often untapped molecular resource. The application of the latest Next-Generation sequencing (NGS) technologies to such specimens allows us to utilise the diverse biobank that is natural history museums. These approaches provide the opportunity to study both extinct or difficul
Objective. To study degree of blood pressure (BP) control in primary healthcare (PHC) treated hypertensive patients in relation to sex, age, drug treatment, and concomitant diseases. Design. Random sample of patients with hypertension. Setting. Ten PHC centres in the Region of Skane, Sweden. Subjects. All the 30- to 95-year-old patients with hypertension who during the period 12 September to 24 Se
