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Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia ARTICLE OPEN Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia Kärt Mätlik 1✉, Daniel R. Garton1,13, Ana R. Montaño-Rodríguez1,13, Soophie Olfat1,2,13, Feride Eren 3, Laoise Casserly1, Anastasios Damdim
Evaluation form for SDI Course Answer Count: 20 What did you like most in the course? Why? What did you like most in the course? Why? The course offered a detailed introduction to SDI concepts. What I liked more was the methodology for the evaluation of an SDI because it presented a good tool for evaluation of SDI as well as other business processes. The course offered a detailed introduction
https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/gisn25_utvardering.pdf - 2026-04-25
Syftet med examensarbetet har varit att utveckla och utvärdera ett realtidssystem som utför analys i molnet och lokalt med hjälp av AWS. De viktigaste målen har varit att skapa ett system som är så snabbt som möjligt och att analysera vilken del av analysen som kan göras i molnet och vilken del som måste göras lokalt. Den förväntade nyttan med systemet är de minskade utvecklings- och underhållskosThe purpose of the degree project has been to develop and evaluate a real-time analysis system which performs analysis in the cloud and locally using AWS. The most important goals have been to create a system which is as fast as possible and to reflect over which part of the analysis can be made in the cloud and which part has to be made local. The expected utility of the system is a consequence o
The 17th September 2001 the distributor Schenker started to cooperate with the computer systems manufacturer Dell to deliver Dell's products to the Nordic market. In the beginning of a new cooperation new processes are formed and they are often developed to solve the local, immediate problems without considering the overall picture. In the distribution network from Dell's plants in Ire
Background Opioid-related deaths have increased in Western countries over recent decades. Despite numerous studies investigating opioid-related mortality, only a few have focused on the lives of the deceased individuals prior to their deaths, specifically regarding contact with care-providing authorities such as health, social and correctional services. Furthermore, a change has been noted in the
Aims. The aim of this paper is to explore and map the age and abundance structure of the stars in the nearby Galactic disk. Methods. We have conducted a high-resolution spectroscopic study of 714 F and G dwarf and subgiant stars in the Solar neighbourhood. The star sample has been kinematically selected to trace the Galactic thin and thick disks to their extremes, the metal-rich stellar halo, sub-
Popular AbstractAvsikten med denna avhandling är att utveckla en teori om de försvårade villkor som män ur arbetarklassen och den lägre medelklassen upplevt i Ronneby sedan början av 1900-talet; om hur traditionen att snabbt komma ut i arbetslivet — som bland män i Ronneby i det närmaste har varit likvärdigt med att bli vuxen — ersatts av ett behov att senarelägga vuxenblivandet. Bakgrunden är attThe place is Ronneby, a smallish town in southern Sweden. My subjects are working class and lower middle class men in Ronneby, men who — since the beginning of the century — have encountered changing conditions for reaching adulthood. In this dissertation, I will analyse these changing and increasingly difficult conditions and try to explain how the tradition of starting to work early in life, and
OBJECTIVE: To compare EuroQol 5-Dimensions (EQ-5D) utility and quality-adjusted life-years (QALYs) in patients with early, methotrexate (MTX) refractory rheumatoid arthritis (RA), randomised to addition of infliximab (IFX) or sulfasalazine and hydroxychloroquine (SSZ+HCQ). METHODS: RA-patients with symptoms <1 year were enrolled between 2002 and 2005 at 15 Swedish centres. After 3-4 months of MTX
Background Multiple myeloma cells uniformly overexpress CD38. We studied daratumumab, a CD38-targeting, human IgG1κ monoclonal antibody, in a phase 1-2 trial involving patients with relapsed myeloma or relapsed myeloma that was refractory to two or more prior lines of therapy. Methods In part 1, the dose-escalation phase, we administered daratumumab at doses of 0.005 to 24 mg per kilogram of body
Changes in the geometry of ocean meridional overturning circulation (MOC) are crucial in controlling past changes of climate and the carbon inventory of the atmosphere. However, the accurate timing and global correlation of short-term glacial-to-deglacial changes of MOC in different ocean basins still present a major challenge. The fine structure of jumps and plateaus in atmospheric and planktic r
Background: Computed tomography (CT) lung densitometry has been demonstrated to be the most sensitive and specific outcome measure for the assessment of emphysema-modifying therapy, but the optimum densitometric index has yet to be determined and targeted sampling may be more sensitive than whole lung assessment. The EXAcerbations and CT scan as Lung Endpoints (EXACTLE) trial aimed to clarify the
Popular Abstract in Swedish Avhandlingen består av fyra kapitel som behandlar olika aspekter av internationell handel och dess effekter på konkurrens och produktivitet. Särskilt behandlas effekterna av EU:s expansion och fördjupade integration. Första kapitlet använder den så kallade gravitationsmodellen för att analysera hur integrationsprocessen av de Central- och Östeuropeiska länderna i EU haThis thesis consists of four papers on trade, competition and productivity with particular emphasis on the effects of various aspects of the deepening and widening of the European Union. The first paper Trade Creation, Diversion and Displacement of the EU Enlargement Process provides an assessment of the effects of the EU enlargement process on trade. A new method of estimating the gravity model
In the wake of the arrival of cloud computing, future applications are poised to become more resilient and adaptive by embracing elasticity in an osmotic manner. Although cloud computing is a strong attractor for application developers, thereare still unconquered performance frontiers. Latency-sensitive and missioncritical applications make up a significant portion of all software systems, and the
The therapeutic management of Sjögren syndrome (SjS) has not changed substantially in recent decades: treatment decisions remain challenging in clinical practice, without a specific therapeutic target beyond the relief of symptoms as the most important goal. In view of this scenario, the European League Against Rheumatism (EULAR) promoted and supported an international collaborative study (EULAR S
Objectives Peak exercise systolic blood pressure (SBP) is associated with future cardiovascular disease (CVD) and mortality. We aimed to evaluate the predictive value of different SBP patterns at the end of exercise with these outcomes. Methods We studied 6329 adults (45% women) referred for exercise testing, with test duration of 6-14 min, maximal effort and valid SBP measurements at the end of e
Microsoft Word - Wahlgren Reimer Bergenståhl.doc Abstrakt—Det finns flera anekdotiska bevis för att lärare och studenter anser att det är stor skillnad på naturvetar- och ingenjörsstudenter. För att ge en utgångspunkt för diskussioner på detta tema presenterar vi här en undersökning av två studentgrupper kemitekniker och naturvetare som läst liknande organkemikurs med samma lärare. De första preli
https://www.lth.se/fileadmin/lth/genombrottet/konferens2008/M_Wahlgren__J_Reimer__B_Bergenstaahl.pdf - 2026-04-24
Omslag Engelska i Lund VT16.pdf 1 m Engelska i Lund Språk- och litteraturcentrum Praktisk information för dig som läser engelska Vårterminen 2017 Mottagningstider registrering, undervisning prov och omprov betyg studievägledning fortsättningskurser studier utomlands och mycket annat 2 Innehållsförteckning Välkommen! 3 Kontakta oss 4 SOL-centrum / LUX 5 Registrering / Studieavbrott 6 Studietakt och
https://www.sol.lu.se/media/utbildning/dokument/kurser/ENGA03/20171/Komplett_fil_klar_V17_1.pdf - 2026-04-24
Plasma 25-Hydroxyvitamin D Concentration and Risk of Islet Autoimmunity Plasma 25-Hydroxyvitamin D Concentration and Risk of Islet Autoimmunity Jill M. Norris,1 Hye-Seung Lee,2 Brittni Frederiksen,1 Iris Erlund,3 Ulla Uusitalo,2 Jimin Yang,2 Åke Lernmark,4 Olli Simell,5 Jorma Toppari,5,6 Marian Rewers,7 Anette-G. Ziegler,8 Jin-Xiong She,9 Suna Onengut-Gumuscu,10 Wei-Min Chen,10 Stephen S. Rich,10
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/82%2001252019_679_082_MP106a_Norris_Diabetes_2017.pdf - 2026-04-25
Podd: AI och etiken – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Podd: AI och etiken 2021-10-29 Vetenskap & hälsa · AI och etiken AI-tekniken öppnar för nya möjligheter inom sjukvården men det finns samtidigt många frågor, inte minst de etiska, som behöver diskuteras. För att ett AI-sys
https://www.vetenskaphalsa.se/ai-etiken/ - 2026-04-25
