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Introduction: The objective was to create a clinically useful prediction model for vaginal birth in trial of labor after one cesarean section, appropriate for a third trimester consultation. Material and methods: Women with one cesarean section and at least one following delivery (N = 38 686) in the Swedish Medical Birth Register, 1998-2013, were studied. The women were randomly divided into one d
SUMMARY: Antibody repertoires reveal insights into the biology of the adaptive immune system and empower diagnostics and therapeutics. There are currently multiple tools available for the annotation of antibody sequences. All downstream analyses such as choosing lead drug candidates depend on the correct annotation of these sequences; however, a thorough comparison of the performance of these tool
The cortico-basal ganglia-thalamic (CBT) circuit is thought to be involved in control of voluntary and goal-directed movements and action selection. Dopamine is known to play a crucial role in this circuit and regulating its activity. The important role of dopamine is particularly evident in Parkinson’s patients, where dopaminergic cells are dying and motor impairments follow. While dopamine repla
The aim of the MIRACHL project is the characterisation and monitoring of in-situ remediation of chlorinated hydrocarbon contamination using an interdisciplinary approach and geophysical methods, such as DCIP (direct current induced polarisation) to investigate the remediation process. To interpret these geophysical field IP data, lab investigations with different kinds of bacteria are necessary to
The cellular mechanisms underlying hereditary photoreceptor degeneration are still poorly understood, a problem that is exacerbated by the enormous genetic heterogeneity of this disease group. However, the last decade has yielded a wealth of new knowledge on degenerative pathways and their diversity. Notably, a central role of cGMP-signalling has surfaced for photoreceptor cell death triggered by
Kolloider, partiklar i storleksordningen en nanometer till en mikrometer, är inom materialvetenskapen attraktiva byggstenar vid konstruktion av olika material eftersom de spontant organiserar sig i periodiska strukturer. Till skillnad från biologiska kolloider såsom proteiner, röda blodkroppar, bakterier och virus, är de syntetiska kolloider som man har tillgång till inom materialvetenskapen i reg
Popular Abstract in Swedish Excess och aktionskonst En semiotisk analys av Hermann Nitschs Das 6-Tage-Spiel Med betoning på första dagens Mittagsfinale Excess and Action Art, A Semiotic Analyze of Hermann Nitschs Das 6-Tage-Spiel, With emphasize on Mittagsfinale the first day I avhandlingen behandlas den österrikiske konstnären Hermann Nitschs Das 6-Tage-Spiel (1998). Syfte att undersöka om och påThe subject for this dissertation is the Austrian artist Hermann Nitsch’s Das 6-Tage-Spiel (1998). The purpose is to examine in what way Das 6-Tage-Spiel, as part of the orgien mysterien theater (hereafter o. m. theater), is an adequate means to realize Nitsch’s intention (as he has described them outside of the work in writings and interviews). Das 6-Tage-Spiel is an example of a category of scen
This thesis presents a comprehensive study of performance characterization and quality control (QC) for the ATLAS Inner Tracker (ITk) silicon strip modules, undertaken in preparation for the High-Luminosity Large Hadron Collider (HL-LHC) upgrade. The work focuses on two aspects: test beam campaigns and thermal cycles. During the test beam campaigns at DESY in October and December 2024, unirradiate
While flying today the customers will receive static advertisements on the screens placed in front of every seat. Hence, the advertisements do not differ depending on the flight’s duration or personal interests. Our goal was to develop a marketing tool where the marketing team at different airlines could specify under which circumstances a certain advertisement would be displayed onboard. The desi
“The death of distance” has become the battle cry of a modern generation of managers, policy makers and scientists who embrace the new globalized economy and its promise of frictionless exchange across the world. While highly influential, this view does not, however, stand unchallenged. Over the last 15 years, there has been a growing interest in the geographical clustering of industry. Well-known
This licentiate thesis examines the development of internationalization of production in Kazakhstan and its economic implications over the period 1991-2010. The main objectives of the thesis are to investigate the role of foreign investment and TNCs in the economic growth of Kazakhstan since its independence in 1991 and onward, to explore the motives that foreign enterprises have for investing in
Popular Abstract in Swedish Jäst kan antingen bryta ner socker direkt till koldioxid och vatten genom andning, eller indirekt via koldioxid och etanol, genom jäsning. Andning är en process som förbrukar syre, och sker därför endast under syrerika (aeroba) förhållanden. Jäsning kräver till skillnad från andning inte tillgång till syre, och kan därför ske under syrefattiga (anaeroba) förhållanden. Under aerobic conditions, most yeasts such as Kluyveromyces lactis, prefer the respiratory pathway and some, such as Saccharomyces cerevisiae prefer less energy efficient fermentative pathway for their energy metabolism. These two metabolic strategies are also known as Crabtree negative and Crabtree positive respectively, and the evolution of the latter has lately been explained by the “make-accum
Many of the original sociological premises, concepts and ideas regarding social action, legal change and social reform were initially formulated by studying conditions specific to Western industrial societies. The socio-cultural consequences of globalisation over the last three decades have, however, affected the relationship between state, law and society, blurred sharply drawn distinctions betwe
Competitiveness of city regions has gained a more and more central position in regional development and regional planning within the last decades. A reason for this is that globalisation has caused pressure on industrial structures forcing firms to increase their competitiveness by more actively promoting innovation and knowledge creation. Access to knowledge has therefore become vital for most ty
Oxygen consumption, lactate production and tissue contents of ATP, phosphocreatine (PCr) and lactate were measured following readdition of K+ to K+-depleted rat portal veins, in order to study the energy turnover associated with Na+/K+ pumping. During incubation in K+-free medium at 37 degrees C spontaneous contractions disappeared in 10-20 min. Readdition of K+ (5.9 mM) after 40 min K+-free incub
Background: Exhaled breath condensate (EBC) is simple to cottect and as such a non-invasive method that has attracted substantial interest in the last few years. However, several methodological concerns have been raised and it has been difficult to reproduce results between different centres. Because of low concentrations of inflammatory markers, potential loss in the sampling system may have grea
Second-generation bioethanol produced from various lignocellulosic materials, such as wood, agricultural or forest residues, has the potential to be a valuable substitute for, or a complement to, gasoline. One of the crucial steps in the ethanol production is the hydrolysis of the hemicellulose and cellulose to monomer sugars. The most promising method for hydrolysis of cellulose to glucose is by
In the last two decades the introduction of mammographic screening in the Western world has increased the number of diagnosed ductal carcinomas in situ (DCIS) considerably. In situ carcinoma of the breast is considered a heterogeneous disease, the natural history of which is not well known. Thus, appropriate treatment needs to be established. For this reason, a randomised trial studying the effect
The large-scale mass mobilizations and colossal demonstrations of the last decade have shown that digital and social media platforms, globally, now play significant roles in early formation and further facilitation of activist movements, interested in progressive causes and societal changes. However, the repercussions of the very same events have also clearly shown the shortcomings of mediatized a
