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Antimicrobial peptides (AMPs) are evolutionarily ancient molecules. They are essential innate immune response molecules that protect organisms from invading pathogens. Tissue factor pathway inhibitors (TFPI-1 and TFPI-2) C-terminal derived peptides exert host defense mechanisms against microbes. Studies showed that in human plasma, C-terminal TFPI-1 and -2 derived peptides mediate bacterial killin
Introduction: Recent haemophilia treatment advances include new recombinant FVIII (rFVIII) products with improved pharmacokinetic (PK) properties that aim to reduce the burden of prophylaxis. These treatments are commonly referred to as extended half-life rFVIII products (EHL rFVIII). There is no uniform definition of what constitutes an EHL rFVIII. Such a definition would help physicians, patient
Background: Nigeria is a major contributor to the global malaria burden. The genetic diversity of malaria parasite populations as well as antibody responses of individuals in affected areas against antigens of the parasite can reveal the transmission intensity, a key information required to control the disease. This work was carried out to determine the allelic frequency of highly polymorphic Plas
It has previously been shown that sera from multiparous women have increased levels of anti-idiotypic antibodies specific for anti-HLA molecules. γ-Globulins prepared from these sera may be superior to commercial preparations of intravenous γ-globulin (IVIg) for inhibiting HLA alloimmunization. To test this, F(ab′)2 fragments prepared from either commercial IVIg or from the sera of men or multipar
Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe a previously unknown antimicrobial mode of ac
Of 30 bacterial species tested 18 stimulated DNA synthesis in human blood lymphocytes. The maximum response was after 3-4 days of culture suggesting a mitogenic effect. This was confirmed by the induction of polyclonal antibody production shown by a plaque assay. Most bacterial species increased the DNA synthesis in B-enriched lymphocytes and unseparated lymphocytes but had negligible activity on
Hu11B6 is a monoclonal antibody that internalizes in cells expressing androgen receptor (AR)-regulated prostate-specific enzyme human kallikrein-related peptidase 2 (hK2; KLK2). In multiple rodent models, Actinium-225-labeled hu11B6-IgG1 ([225Ac]hu11B6-IgG1) has shown promising treatment efficacy. In the present study, we investigated options to enhance and optimize [225Ac]hu11B6 treatment. First,
13 april 2026 15:30 till 16:30 | Seminarium Experience powerful firsthand insights on social, economic, and environmental sustainability as Lund University students return from fieldwork across the world. Join a dynamic session where real stories and sharp perspectives bring global sustainability challenges to life through student research. This event focuses on global sustainability challenges ba
https://www.medicin.lu.se/evenemang/minor-field-studies-exploring-sustainability-insights-around-world - 2026-05-28
Photomultiplier tube (PMT) nonlinearities relevant for single shot high-speed lifetime phosphor thermometry were investigated by simulating decay curves with a light emitting diode (LED) at repetition rates between 1 Hz and 10 kHz. The PMT gain, LED decay time, and background radiant flux were also varied to investigate their impact on the measured decay time error. Errors in the measured decay ti
Kära medlemmar i Nordic Network for Narratives in Medicine! Vi hoppas att 2023 börjat bra på alla sätt! Här kommer årets första nyhetsbrev och vi passar på att påminna läsarna om att skicka information till mig (Åsa) som ni tror att era med-medlemmar har intresse av. Har ni tankar kring ett möjligt tema för nästa nordiska nätverksmöte (i Trondheim), mejla gärna Katarina.Bernhardsson@litt.lu.se Art
13 april 2026 15:30 till 16:30 | Seminarium Experience powerful firsthand insights on social, economic, and environmental sustainability as Lund University students return from fieldwork across the world. Join a dynamic session where real stories and sharp perspectives bring global sustainability challenges to life through student research. This event focuses on global sustainability challenges ba
https://www.lu.se/evenemang/minor-field-studies-exploring-sustainability-insights-around-world - 2026-05-28
CHINA NATIONAL LAW AND POLICY REPORT CONSULTATION DRAFT 2020 Displacement in the Context of Disasters and Climate Change Funded by This report was prepared by Sri Aryani (RWI) and Matthew Scott (RWI) 2020 TABLE OF CONTENTS 1 INTRODUCTION 1 1.1. A human rights-based approach 1 2 Displacement in Numbers 3 2.1. Number of disasters and people affected in the last ten years (2009–2018) 3 3 Recommendati
https://rwi.lu.se/wp-content/uploads/2024/03/Consultation-Draft_China.pdf - 2026-05-26
NYTT FRÅN LUNDS UNIVERSITET Mejlutskick på svenska och engelska som vänder sig till fakultetskommunikatörer vid Lunds universitet för vidarespridning i fakultets- och institutionskanaler – Nr 10 v 11 - 2021. CORONARELATERAT Fler studieplatser öppnas upp för de som måste uppehålla sig på campus Universitetet har justerat sitt beslut så att fler studieplatser kan öppnas upp samtidigt som miljöerna s
https://www.cec.lu.se/sites/cec.lu.se/files/2021-03/LU-gemensamt%20Mejlutskick%20Nr%2010-v11-2021_.pdf - 2026-05-28
One of the most important trends in contemporary tourism is the increase in urban tourism, both in absolute and in relative terms. An increasing number of cities have become significant tourism destinations. Cities also attract an increasingly diverse set of visitors, some of which could be called alternative tourists. The development of alternative tourism is related to decreasing relative costs
28 maj 2026 17:00 till 19:00 | Seminarium Welcome to an evening seminar on art in campus environments 17:00 Opening Annie Lindberg, Director of Skissernas Museum, welcomes guests.Introduction Marcus Rancken, Strategic Property Developer and Head of Art, and Lotta Mossum, Head of the Art Unit, introduce the collaboration between the Public Art Agency Sweden and Akademiska Hus.Background Moderators
