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Application of frequency and sample entropy to discriminate long-term recordings of paroxysmal and persistent atrial fibrillation

Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. At an early stage of the disease, AF may terminate spontaneously and is then referred to as paroxysmal AF. On the other hand, when external intervention is required for the arrhythmia to terminate, it is referred to as persistent AF. In this work, a method to discriminate between paroxysmal and persistent AF in the long-t

Expression of GADS enhances FLT3-induced mitogenic signaling.

GADS is a member of a family of SH2 and SH3 domain-containing adaptors that functions in tyrosine kinase-mediated signaling cascades. Its expression is largely restricted to hematopoietic tissues and cell lines. Therefore, GADS is mainly involved in leukocyte-specific protein tyrosine kinase signaling. GADS is known to interact with tyrosine-phosphorylated SHC, BCR-ABL and KIT. The SH2 domain of G

Parametric quantification of myocardial ischaemia using real-time perfusion adenosine stress echocardiography images, with SPECT as reference method.

Summary Background: Real-time perfusion (RTP) adenosine stress echocardiography (ASE) can be used to visually evaluate myocardial ischaemia. The RTP power modulation technique, provides images for off-line parametric perfusion quantification using Qontrast((R)) software. From replenishment curves, this generates parametric images of peak signal intensity (A), myocardial blood flow velocity (beta)

Tensions between academic and vocational demands

One of the most important routes to employment within the social welfare sector worldwide is higher education, which equips students not only with the knowledge for employment, but with the tools to use and build on this knowledge. During the last few decades there has been an academic drift in professional education, especially for many shorter professional programmes. Many of these shorter progr

Riverine sources of bioreactive macroelements and their impact on bacterioplankton metabolism in a recipient boreal estuary

The loading of terrestrially derived macroelements, such as dissolved organic carbon (DOC), total nitrogen (N), and total phosphorus (P), to inland and estuarine waters is increasing in the northern hemisphere. Thesemacroelements often limit heterotrophic bacterioplankton metabolism (production and respiration), which in turn influence food web structures, exchange of greenhouse gases between the

A Review and Typology of Circular Economy Business Model Patterns

The circular economy (CE) requires companies to rethink their supply chains and business models. Several frameworks found in the academic and practitioner literature propose circular economy business models (CEBMs) to redefine how companies create value while adhering to CE principles. A review of these frameworks shows that some models are frequently discussed, some are framework specific, and so

How Colleagues Can Support Each Other’s Needs and Motivation : An Intervention on Employee Work Motivation

Organisations have flattened and increasingly rely on teamwork. Therefore, colleagues play an increasingly important role in stimulating employee motivation. Adopting Self-Determination Theory as a guiding framework, the aim of this field experiment was to examine whether team members can be trained in supporting each other's basic psychological needs for autonomy, competence, and relatedness and,

A practical method for measuring the ion exchange capacity decrease of hydroxide exchange membranes during intrinsic degradation

In this work we present a practical thermogravimetric method for quantifying the IEC (ion exchange capacity) decrease of hydroxide exchange membranes (HEMs) during intrinsic degradation mainly occurring through nucleophilic attack of the anion exchanging group by hydroxide ions. The method involves measuring weight changes under controlled temperature and relative humidity. These conditions are cl

Differential gene expression of Plasmodium homocircumflexum (lineage pCOLL4) across two experimentally infected passerine bird species

Plasmodium parasites are present in a wide range of host species, some of which tend to be more susceptible than others, potentially as an outcome of evolved tolerance or resistance. Common starlings seem to cope with malaria infection while common crossbills are more susceptible to the same infections. That raises the question if the parasites rely on the same molecular mechanisms regardless of h

Geothermal ecosystems as natural climate change experiments : The ForHot research site in Iceland as a case study

This article describes how natural geothermal soil temperature gradients in Iceland have been used to study terrestrial ecosystem responses to soil warming. The experimental approach was evaluated at three study sites in southern Iceland one grassland site that has been warm for at least 50 years (GO), and another comparable grassland site (GN) and a Sitka spruce plantation (FN) site that have bot

Whole-mount in situ hybridization and immunohistochemistry in Xenopus embryos.

Xenopus is a favorable experimental model in developmental biology. With its fast and external development, high number of progeny and large size, early embryos are well suited for micromanipulation to study the function of genes with relevance to human diseases. In this chapter, we present a combined method for lineage tracing and whole-mount in situ hybridization. In addition, we present protoco

Prediction of Postoperative Pain from Electrical Pain Thresholds after Laparoscopic Cholecystectomy

OBJECTIVE:: Early postoperative pain correlates to persisting pain, psychosocial distress, and delayed mobilization with thromboembolic and infectious complications. Electrical pain thresholds (EPT) have shown promising results in being able to predict postoperative pain, but the results are conflicting. The aim of this study was to test whether EPT levels can be used to predict postoperative pain

Composition of supported model membranes determined by neutron reflection

We have investigated the formation of supported bilayers by coadsorption of dipalmitoyl phosphatidylcholine (DPPC) with the nonionic surfactant P-D-dodecyl maltoside. The adsorption of mixed phospholipid-surfactant micelles on hydrophilic silica surfaces at 25 degrees C was followed as a function of bulk concentration by neutron reflection. Using chain-deuterated d(25)-beta-D-dodecyl maltoside and

Towards operational remote sensing of forest carbon balance across Northern Europe

onthly averages of ecosystem respiration (ER), gross primary production (GPP) and net ecosystem exchange (NEE) over Scandinavian forest sites were estimated using regression models driven by air temperature (AT), absorbed photosynthetically active radiation (APAR) and vegetation indices. The models were constructed and evaluated using satellite data from Terra/MODIS and measured data collected at