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GPR30, or G protein-coupled estrogen receptor (GPER), is a G protein-coupled receptor (GPCR) that is currently attracting considerable attention in breast cancer and cardiometabolic regulation. The receptor was reported to be a novel membrane estrogen receptor mediating rapid non-genomic responses. However, questions remain about both the cognate ligand and the subcellular localization of receptor
BACKGROUND: Special neck support pillows claiming to improve rest and reduce neck pain are currently being advertised.OBJECTIVE: To test whether neck pillows have any positive effect on neck pain and quality of sleep compared with usual pillows and, if so, to find the optimal characteristics of such a pillow.METHODS: Thirty-seven hospital employees and 18 neck patients were asked to test six neck
We demonstrate a new screening method for obtaining a prostate-specific antigen (PSA) binding aptamer based on an acoustofluidic separation (acoustophoreis) technique. Since acoustophoresis provides simultaneous washing and separation in a continuous flow mode, we efficiently obtained a PSA binding aptamer that shows high affinity without any additional washing step, which is necessary in other sc
This dissertation focuses primarily on the following aspects concerning music in theatre: 1) its experienced peculiarity – ontologically grounded, 2) its sounding scope, and 3) its various kinds of functions. I argue that the difference between spoken theatre and opera is a question of degree rather than essence, and consider such an assertion being especially valid for the music of these genres.
I projektet har ett verktyg eller metod för bestämning av risk i vårdavdelningar tagits fram. Verktyget, Brandskyddsvärdering av vårdavdelningar (BSV-vård) kan användas för att bestämma den relativa säkerheten för olika avdelningar vad avser brand. Meningen är att BSV-vård skall kunna användas som ett komplement vid brandsyn. Verktyget kan också tjäna som checklista vid nyproduktion då den också g
1. Background The workgroup of Traffic Psychology is concerned with the social, behavioral, and perceptual aspects that are associated with use and non-use of bicycle helmets, in their various forms and under various cycling conditions. 2. Objectives The objectives of WG2 are to (1) share current knowledge among the people already working in the field, (2) suggest new ideas for research on and eva
This paper provides a production and consumption-based empirical macroeconomic-climate assessment of Sweden’s CO2 emissions. The core methodology is based on three complementary quantitative methods, namely energy-economy-environment indicators, econometric analyses, and a multi-regional input output (MRIO) sectoral model. Based on the latest available data (1971–2011), indicators show a sharp dec
An algal-bacterial consortium formed by Chlorella sorokiniana and a phenanthrene-degrading Pseudomonas migulae strain was able to biodegrade 200-500 mg/l of phenanthrene dissolved in silicone oil or tetradecane under photosynthetic conditions and without any external supply of oxygen. Phenanthrene was only removed when provided in organic solvent, which confirms the potential of two-phase systems
Near infrared (NIR) transmission spectroscopy is a promising method for fast quantitative measurements on pharmaceutical tablets, but there are still some problems to overcome in order to incorporate the technique as a control tool in tablet production. The main problem is the limited precision for multivariate calibrations based on NIR transmission data. The precision is affected by several facto
Background: Interferon beta-1a (IFNbeta-1a; Avonex) is effective for the treatment of relapsing MS; however, the optimal dose of IFNbeta-1a is not known. Objective: To determine whether IFNbeta-1a 60 mug IM once weekly is more effective than IFNbeta-1a 30 mug IM once weekly in reducing disability progression in relapsing MS. Methods: In a double-blind, parallel-group, dose-comparison study, 802 pa
Popular Abstract in Swedish Syftet med studien var att utvärdera förändringar avseende psykologiska och sociala variabler före och efter gruppterapi för vuxna kvinnor som utsatts för sexuella övergrepp i barndomen. Ytterligare syften var att beskriva och genom "consumer satisfaction" utvärdera den traumafokuserade gruppterapin, att beskriva kvinnornas hälsa före gruppterapistart och att utvärdera The aim of the study was to evaluate changes in psychological and social variables before and after group therapy for adult women who were sexually abused in childhood. Other aims were to describe and evaluate the traumafocused group therapy by consumer satisfaction, to describe the women's health before group therapy start and to evaluate the impact of single childhood sexual abuse variables on m
Abstract in Danish Afhandlingens hovedproblemstillinger er: Hvilken betydning har det for danske socialarbejderes vurderinger og handlinger i børnefamiliearbejdet, at et barn og dets familie ikke er etniske danskere? Denne problemstilling undersøges gennem tre empiriske undersøgelser: Familieplejeundersøgelsen består af en journalundersøgelse af 44 anbragte etniske minoritetsbørns journaler samt The dissertation studies how social workers ensure continuity in relation to the individual child's background when placing and working with children of ethnic minority background in care. This is studied through 44 sets of case study notes from a foster-care association and interviews with 10 foster-care consultants. These two types of data are analysed through three perspectives: a continuity pe
This thesis consists of three self-contained papers in theoretical and computational macroeconomics and growth theory with income inequality and human capital accumulation as common themes. The first paper investigates what level of income tax progressivity is welfare-optimal given modern patterns of income inequality in the US. The paper develops a model for endogenous income inequality that fits
This paper presents an innovative research on urban risk reduction and climate change adaptation that combines case studies, grounded theory and systems analysis, which could be used as a template for similar intersectoral and interdisciplinary investigations. Such a ‘case studies–grounded theory–systems analysis approach’ permits a grounded theory to be built from case study data, which is viewed
Industry involvement in open source software development has become a popular practice among companies which, e.g., share software development costs with other community participants or implement an open source based business model. An increased understanding of the underlying development structure, especially in a case where the community participants are composed of competing industry members, c
Background. Giant cell tumor of bone (GCTB) is an aggressive primary osteolytic tumor. GCTB often involves the epiphysis, usually causing substantial pain and functional disability. Denosumab, a fully human monoclonal antibody against receptor activator of nuclear factor. kappa beta ligand (RANKL), is an effective treatment option for patients with advanced GCTB. This analysis of data from an ongo
Tvångsomhändertagande av unga har på grund av dess ingripande karaktär länge varit föremål för samhällsdebatt. Lagen med särskilda bestämmelser om vård av unga stadgar de materiella förutsättningarna för staten att tvångsvis vårda den unge. Med tanke på att ett tvångsomhändertagande in-nebär ett allvarligt ingrepp i den personliga integriteten är det ur ett rättssäkerhetsperspektiv av avgörande beCompulsory treatment of young persons has, due to its intrusive charachter, been the subject of debate for a long time. The Care of Young Person Act states the prerequisites for the state to coercive care young in need. Considering that compulsory treatment is to be seen as a serious interference with the personal integrity, it is from a legal certainty perspective of crucial importance that the c
