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A complex reaction mechanism of oxidation of the anti-tubercular prodrug isoniazid (isonicotinic hydrazide, INH) by [IrCl6]2− as a model for redox processes of such drugs in biological systems has been studied in aqueous solution as a function of pH between 0 and 8.5. Similar experiments have been performed with its isomer nicotinic hydrazide (NH). All reactions are overall second-order, first-ordA complex reaction mechanism of oxidation of the anti-tubercular prodrug isoniazid (isonicotinic hydrazide, INH) by [IrCl6]2− as a model for redox processes of such drugs in biological systems has been studied in aqueous solution as a function of pH between 0 and 8.5. Similar experiments have been performed with its isomer nicotinic hydrazide (NH). All reactions are overall second-order, first-ord

Post hoc interventions rely on having access to certain personal data - such as the gender, age, ethnicity, and sexual orientation of the persons being evaluated - in order to detect and correct for prejudice. This brings these interventions into possible tension with pertinent data protection legislation, which might restrict the processing of said data. We discuss the compatibility of post hoc i

Background: Parents of children with complex right ventricular outflow tract (RVOT) anomalies are con-fronted with their child’s need for heart surgery early in life and repeated reoperations later on. Preoperative assessment needs to be performed whenever an indication for reoperation is suspected. The aim was to illuminate the experiences of parents of children diagnosed with RVOT anomalies, in

How do we design policies that support a shift in eating habits towards a diet that includes more vegetable-basedproducts and less meat, and in particular red meat? To inform policy, more information is needed about consumers’perceptions of the plant-based protein alternatives that have become available on the market. The present study of 1000 Danish consumers examined oat drink and plant-based miHow do we design policies that support a shift in eating habits towards a diet that includes more vegetable-based products and less meat, and in particular red meat? To inform policy, more information is needed about consumers' perceptions of the plant-based protein alternatives that have become available on the market. The present study of 1000 Danish consumers examined oat drink and plant-based

Background: For up to 50% of adolescents experiencing PTSD, the course of their illness is further complicated by co-occurring substance use. Despite this, evidence-based integrated treatment options for adolescents with this comorbidity remain sparse. To address this gap, we are conducting an RCT examining the efficacy of exposure-based therapy for co-occurring PTSD and substance use among adoles

In this article we discuss how two types of popular romances – the desert romance and the governess romance – have blended into what we refer to as the desert-governess romance. In the world of romance, the governess and the sheikh may be an odd couple but they do make good bedfellows. Etymologically speaking, the governess (“A woman who holds or exercises authority” (OED)) is the perfect love matIn this article we discuss how two types of popular romances – the desert romance and the governess romance – have blended into what we refer to as the desert-governess romance. In the world of romance, the governess and the sheikh may be an odd couple but they do make good bedfellows. Etymologically speaking, the governess (“A woman who holds or exercises authority” (OED)) is the perfect love mat

Background: Over the past decade, several PET tracers were developed to visualise and quantify tau pathology in vivo. However, all these tracers have distinct off-target binding, different dynamic ranges and likely different levels of non-specific binding resulting in large variability in semiquantification. We propose to standardise the sampling and the quantification across all available tau tra

Employing the Foucauldian term ‘conduct’, this article explores how social resilience and morale became a target of state intervention in Denmark during the Cold War. ‘Psychological defence’ was a Cold War phenomenon designed to bring an imagined future war into a space of control as well as a tool for the authorities’ exercise of power in case another world war became a reality. Advocating a meth

This paper addresses the consensus problem and the formation problem on SE(3) in multi-agent systems with directed and switching interconnection topologies. Several control laws are introduced for the consensus problem. By a simple transformation, it is shown that the proposed control laws can be used for the formation problem. The design is first conducted on the kinematic level, where the veloci

Abstract In this contribution, party autonomy is discussed in relation toEuropean family and succession law. The topic is briefly introduced, followedby a survey covering the main EU-instruments with particular emphasis onthe parties’ possibility to influence choice of court and law by agreements.Thus, autonomy as described in this contribution embraces both prorogationand choice of law. The contr

Background: In luminal breast cancer, adjuvant CDK4/6 inhibitors (eg, abemaciclib) improve invasive disease-free survival. In patients with T1–2, grade 1–2 tumours, and one or two sentinel lymph node metastases, completion axillary lymph node dissection (cALND) is the only prognostic tool available that can reveal four or more nodal metastases (pN2–3), which is the only indication for adjuvant abe

Introduction Anorectal malformations (ARMs) are complex congenital anomalies of the anorectal region, oftentimes also affecting the genitourinary system. Although successful surgical correction can often be achieved in the neonatal period, many children will experience functional problems in the long term. The European Reference Network for rare and complex urogenital conditions (eUROGEN) assemble

In this report, the effectiveness of a detector-activated water mist system, Q-fog, has been compared to traditional residential sprinklers. In total, eight tests were performed with a realistic fuel (bed with pillow and duvet) based on the test procedure described in LPS 1655. The bed was placed at different locations in the room and was ignited at the pillow and below the bed, also according to In this report, the effectiveness of a detector-activated water mist system, Q-fog, has been compared to traditional residential sprinklers. In total, eight tests were performed with a realistic fuel (bed with pillow and duvet) based on the test procedure described in LPS 1655. The bed was placed at different locations in the room and was ignited at the pillow and below the bed, also according to

The aim is to explain why union density is not only considerably higher in the Ghent country Sweden than in non-Ghent Norway but also why it has declined much more in Sweden, in par-ticular among blue-collar workers. We show how changes to Swedish unemployment insurance in 2007–2013 were followed by a decline in union density and how white-collar unions were more successful than blue-collar unionsThe aim is to explain why union density is not only considerably higher in the Ghent country Sweden than in non-Ghent Norway but also why it has declined much more in Sweden, in particular among blue-collar workers. We show how changes to Swedish unemployment insurance in 2007–2013 were followed by a decline in union density and how white-collar unions were more successful than blue-collar unions

Purpose: A better knowledge of how deadwood decomposes is critical for accurately characterizing carbon and nutrient cycling in forests. Fungi dominate this decomposition process, but we still have limited understanding of fungal community structuring that ultimately controls the fate of wood decomposition. This is particularly true in tropical ecosystems. To address this knowledge gap, our study

Background: Women with breast cancer have different chances of surviving their disease, depending on where they live. Variations in survival may stem from unequal access to prompt diagnosis, treatment and care. Implementation of the right to health may help remedy such inequalities. The right to health is enshrined in international human rights law, notably Article 12 of the International Covenant

The development of sensitive, convenient, and cost-effective methods for detecting disease biomarkers is very important for meeting the growing demand for early clinical diagnosis. Additionally, the detection of disease biomarkers at ultralow concentrations is very important for disease prevention and treatment and posttreatment rehabilitation. However, current ultrasensitive detection strategies

In 2018, a strategy for Sweden's first National Forest Program was launched. As part of its implementation, County Administrative Boards have initiated dialogue processes for drafting regional forest strategies. Stakeholder deliberation is ascribed the potential to promote trust and mutual understanding, lead to more robust decisions and smoother implementation. We examine the dialogue processes,