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Genome-wide association studies (GWASs) have shown that common genetic variation contributes to the heritable risk of childhood acute lymphoblastic leukemia (ALL). To identify new susceptibility loci for the largest subtype of ALL, B-cell precursor ALL (BCP-ALL), we conducted a meta-analysis of two GWASs with imputation using 1000 Genomes and UK10K Project data as reference (totaling 1658 cases an

BackgroundA novel non-invasive method for generation of pressure volume loops (PV-loops) using brachial blood pressure and cardiovascular magnetic resonance (CMR) imaging has recently been presented and validated (1). The non-invasive nature of this method enables calculation of PV-loops in large patient cohorts previously not feasible due to the need of invasive measurements.PurposeThe purpose of

Title:Creativity and the evolvement of culture. The altering capacity of art works.Creativity, in the sense finding original solutions to life world problems, can be seen as the principal force of cognitive and communicational genesis, such as when new verbal language elements occur (Heine/Kuteva 2007). Creativity has been defined as the original act that not only makes a radical “revision of a co

This data package contains high accuracy CO2 dry air mole fractions from 58 ICOS and non-ICOS European observatories at in total 132 observation levels, collected by the ICOS Atmosphere Thematic Centre (ATC) and provided by the station contributors. The package is part of the Globalviewplus v8.0 data product, released in 2022 and is intended for use in carbon cycle inverse modeling, model evaluati

The interdisciplinary cooperation project »Summer of the Arts« showed works by the 2022/2023 and 2023/2024 recipients of the Villa Massimo’s German Rome Prize in eight institutions in Stuttgart. The Staatsgalerie Stuttgart presented the art created by Yael Bartana, Manaf Halbouni, and Bjørn Melhus during their stays in Rome in dialogue with works from the Staatsgalerie collection.

In this paper I develop a view of the distinction between fake and genuine properties occurring in laws of nature.

The response of a NE-213 liquid-scintillator detector has been measured using tagged neutrons from 2 to 6 MeV originating from an Am/Be neutron source. The neutron energies were determined using the time-of-flight technique. Pulse-shape discrimination was employed to discern between gamma-rays and neutrons. The behavior of both the fast (35 ns) and the combined fast and slow (475 ns) components of

The 6th Haemophilia Global Summit was held in Prague, Czech Republic, in September 2015. The programme was designed by an independent Scientific Steering Committee of haemophilia experts and aimed to share optimal management strategies for haemophilia at all life stages, explore recent potential advances in the management of haemophilia A and B and discuss challenges in haemophilia care. In this s