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Background and hypothesis: KDIGO recommends proteinuria <1 g/d as a treatment target in patients with immunoglobulin A nephropathy (IgAN) because of high risk of progression to kidney failure. However, long-term kidney outcomes in patients with low-grade proteinuria remain insufficiently studied. Methods: We enrolled patients with biopsy-proven primary IgAN from the Swedish Renal Registry and anal
Aerosolised Polystyrene Latex (PSL) nanoparticles are, due to their well-defined size, spherical shape, and inert surface, useful in many experimental applications, including studies of particle deposition in the human lung. Aerosolising nanoparticles entails added challenges, and nanoparticles can potentially be more hazardous than otherwise equivalent microparticles. The objective of this work w
Solar energy is a renewable energy source which in the long term is important to develop because the usage does not effect the environment in a negative way. Increased energy exchange and cheaper production costs for solar collectors and solar cells are main factors in making the solar energy commercially successful in the future. Small scale solar collector systems are most common today because t
Till följd av covid-19-pandemin har frågan om regeringen bör få utökade normgivningsbefogenheter under fredstida kriser diskuterats flitigt. Den 27 november 2023 föreslog en parlamentariskt sammansatt kommitté i betänkandet SOU 2023:75 att regeringen bör få utökade normgivningsbefogenheter under allvarliga fredstida kriser. I huvudsak föreslår kommittén både att regeringen ska få lov att bemyndigaIn the aftermath of the Covid-19 pandemic the issue of whether the Government’s regulatory power should be increased in times of peacetime crises has been widely debated. On November 27, 2023, an all-party Committee proposed in the report SOU 2023:75 that the Government should be given increased regulatory powers during serious peacetime crises. In essence, the Committee proposes both that the Rik
Denna uppsats har klargjort utvecklingen av våldtäktsdefinitionen och det rättsliga skyddet mot våldtäkter i väpnade konflikter sedan 1900-talet. En rättsdogmatisk metod har använts med betoning på folkrättens rättskällelära, där två centrala frågeställningar har granskats. Denna studie har utrett gällande rätt, inklusive tre banbrytande rättsfall: Akayesu, Furundžija och Kunarac. Uppfattningen This thesis has clarified the development of the definition of rape and the legal protection against rape in armed conflicts since the 1900s. A legal dogmatic method has been used with an emphasis on the sources of law in international law, where two central research questions have been reviewed. This study has examined current law, including three groundbreaking legal cases: Akayesu, Furundžija a
Retrospective, propensity-score-adjusted (PSA) studies have indicated to practitioners in the field that contrast-induced acute kidney injury (AKI) after contrast-enhanced CT (CECT) is of minor importance or even non-existent. This has led to controversies between clinicians demanding CECT not to miss any diagnoses and radiologists reluctant or even refusing CECT in risky patients. A critical revi
The radiative properties of clouds depend partially on the cloud droplet number concentration, which is determined by the concentration of cloud condensation nuclei (CCN) when the clouds are formed. In turn, CCN concentrations are determined by the atmospheric particle size distribution and their chemical composition. We use a novel Lagrangian modelling framework to examine the origins and history
This thesis presents investigations for the improvement of electrical contact and catalytical properties of two fungal redox enzymes, cellobiose dehydrogenase (CDH) and pyranose dehydrogenase (PDH), with electrodes and the use of the prepared electrodes as carbohydrate biosensors and in enzymatic biofuel cells. The performance of enzyme modified electrodes can be improved in two ways, by modifying
Popular Abstract in Swedish Förebyggande av hjärtkärlsjukdom har varit en utmaning för medicinsk forskning under flera decennier. Viktiga frågeställningar om såväl screeningmetodik som risk-faktor intervention söker fortfarande sitt svar och har i sig betydelse för både samhällsmedicin och klinisk verksamhet. Målsättningen för denna studie var att undersöka möjligheten för läkare och sjuksköterskoCardiovascular disease prevention has been a challenge for research for decades. The studies of this thesis were designed to investigate the role of health professionals in everyday clinical work based upon the concept of comprehensive primary care consultation. Routine check-up of blood pressure was the basis for the inclusion in an opportunistic screening for hyperchol-esterolaemia. Additionally
Popular Abstract in Swedish Populärvetenskaplig sammanfattning: När udda blir mainstream - om stress och likriktning i växtsamhället I skogen råder stress på många sätt, och precis som i det mänskliga samhället har stressen i växtsamhället ökat under de senaste decennierna. Dessa händelser har heller inte skett oberoende av varandra. Vårt allt snabbare tempo med krav på ökad tillväxt har inte baSoil acidification has become a source of serious concern in many parts of the world. In southern Sweden, the deposition of acidifying substances, such as nitrogen and sulphur compounds, has decreased the mean pH of forest soils by almost one unit since the 1950s. Apart from H+ ions themselves being harmful to plant roots, the potential toxicity of aluminium (Al) is increased when pH drops below 5
This study investigates how feminist health discourse is collaboratively produced on Xiaohongshu, a Chinese social media platform known for its female-dominated user base and stringent censorship environment. Focusing on the account Pause in Dialogue, the thesis explores how stigmatized topics such as menstruation, sexual health, and bodily discomfort are reframed through multimodal strategies and
Samhället idag kännetecknas av digital interaktion, där både privata såväl som yrkesmässiga kontakter sker via olika tekniska plattformar. Människor skrol-lar, kommunicerar och tar till sig information via mobiltelefoner eller datorer vilket har blivit det normala sättet att interagera i vardagen. Allt fler rättsområ-den har tagit digitaliseringen i beaktning, men det finns fortfarande rättsområ-dSociety today is characterized by digital interaction, with both private and pro-fessional contacts taking place through various technological platforms. Peo-ple browse, communicate and absorb information via mobile phones or com-puters, which has become the normal way of interacting in everyday life. More and more areas of law have taken digitalization into account, but there are still areas of l
In the last decade, the idea of total defence – a whole-of-society approach integrating civilian and military capabilities – has gained renewed prominence in Europe, including within the European Union (EU). Concurrently, the concept of strategic autonomy – the EU’s ability to act independently – has emerged as a central feature in its security policy, driving ambitions for ‘a quantum leap forward
Background: The benefit of surgical resection for colorectal cancer (CRC) lung metastases is unclear. The aim was to investigate the incidence, treatment strategy, and 5-year overall survival (OS) in CRC patients with isolated lung metastases. Methods: This registry-based retrospective cohort study included patients treated with curative resection of CRC within the county of Skåne during the perio
Electric buses are increasingly popular in public transport systems globally, and in many European contexts, this transition takes place through public procurement. While previous research argues that electrification challenges existing procurement practices and strategies, the aim of the paper is to contribute new knowledge on the role of public procurement in the transition to electric buses andElectric buses are increasingly popular in public transport systems globally, and in many European contexts, this transition takes place through public procurement. While previous research argues that electrification challenges existing procurement practices and strategies, the aim of the paper is to contribute new knowledge on the role of public procurement in the transition to electric buses and
The Nordic countries have been described as generous front-runners in their development assistance, making observers suggest the existence of a ‘Nordic Model’. They have been claimed to play a leadership role in a European and global context. Recently, however, this characterisation has been challenged due to changes in Nordic policies and in the external environment. We investigate the developmenThe Nordic countries have been described as generous front-runners in their development assistance, making observers suggest the existence of a ‘Nordic Model’. They have been claimed to play a leadership role in a European and global context. Recently, however, this characterisation has been challenged due to changes in Nordic policies and in the external environment. We investigate the developmen
Structural components such as those used in gas turbines for energy conversion applications, are subjected to high loads at elevated temperatures. In order to ensure that the components survive under these conditions for a sufficiently long time, it is imperative to select materials with good high temperature properties like strength and corrosion resistance. Such materials are usually alloys with
Abstract Due to developments in the last decades in the field of protein production, new technologies for bio-separation have evolved. Especially in the field of affinity chromatography, the search for new ligands is of great interest. Besides the antibodies used as affinity ligands, synthetic ligands were introduced. Textile dyes were a first group to be introduced but despite their selectivity a
Conceptual design is the first phase in the design process in which all the requirements and design objectives are synthesized into conceptual alternatives. In practice today, major decisions regarding the buildings geometry, massing, and overall form are usually made during the first phase. Considering structural performance requirements during conceptual design enhances interdisciplinary interac
