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The combination of glucagon and glucagon-like peptide-1 (GLP-1) has been suggested as an approach to target obesity, since the two hormones have complementary action on body weight. We examined whether complementary action of the two hormones also exist on insulin secretion. Female C57BL/6 mice were injected intravenously with glucose with or without GLP-1, glucagon or the combination of GLP-1 and
We present an evaluation of a nested high-resolution Goddard Earth Observing System (GEOS)-Chem chemistry transport model simulation of tropospheric chemistry over tropical South America. The model has been constrained with two isoprene emission inventories: (1) the canopy-scale Model of Emissions of Gases and Aerosols from Nature (MEGAN) and (2) a leaf-scale algorithm coupled to the Lund-Potsdam-
The purpose of the research was to enrich the understanding of the process of corporatization of higher education and to demonstrate the importance of studying identity work. We conducted an inductive case study research basing our methods and methodology on hermeneutics and an interpretive paradigm. We developed our argumentation on the basis of interpretive and critical theory regarding identity
Hedersrelaterat våld är för svenskt vidkommande inte längre ett främmande begrepp eller fenomen. Inte desto mindre är ämnet politiskt laddat och debatten om hedersrelaterat våld är fortfarande högaktuell. Inte minst på det straffrättsliga området gör sig problematiken gällande och det tycks råda en oklarhet kring vilken betydelse heder bör ha i rättsliga sammanhang. Hedersrelaterat våld är ett kViolence in the name of honour is no longer an unknown concept or phenomenon in the Swedish society. Nevertheless, the issue is subject of an ongoing political debate. The problematic aspects of violence in the name of honour are evident within the criminal justice system and there appears to be inherent uncertainties regarding the role of honour in the legal context. Violence in the name of hon
BACKGROUND: CFTR modulators, including Elexacaftor/Tezacaftor/Ivacaftor (ETI), have markedly improved clinical outcomes for people with cystic fibrosis (pwCF), but the molecular impact on airway inflammation remains incompletely understood. This study aimed to characterise longitudinal changes in airway inflammation and sputum proteomes following ETI treatment.METHODS: Sputum from pwCF (n = 30) wa
The main aim of this study was to apply and compare two GIS-based data mining models, namely support vector machine (SVM) by four kernel functions (linear-SVM, polynomial-SVM, radial basic function-SVM, and sigmoidal-SVM) and entropy models in landslide susceptibility mapping, in Shangzhou District, China. Initially, 145 landslide locations were mapped using early reports, aerial photographs, and
Research suggests that polyphenols, such as anthocyanins, that are found in considerable amounts in many types of berries, contributes with a positive effect on human cognition. However, clinical trials are warranted to support these findings. Preparation for such a trial includes developing a berry-rich study product and a corresponding reference beverage. Phenolic compounds are highly unstable a
Gängkriminaliteten har under det senaste decenniet ökat i Sverige och hårdare tag har efterfrågats. Tidöavtalet anger att det är av högsta vikt att bekämpa gängkriminaliteten i Sverige och i början på 2023 lämnade regeringen in en proposition till riksdagen som bland annat föreslog straffskärpningar för vissa straffskalor för brottstyper som är vanliga inom kriminella nätverk. Enligt propositionenThe past decade has witnessed a rise in gang-related violence and crime in Sweden, which has caused a debate prompting calls for more stringent measures. In early 2023, the government submitted a proposition to the parliament which included proposals for stricter penalties för certain crime categories commonly associated with criminal networks. According to the proposition, increased penalty scale
The central issue discussed in this thesis is the “essayistic mode”, which is usually described as a set of themes and characterization of the traditional written essay. In our more digitalized world today, it has been argued that some of these essayistic traits could be identified in other types of media, for example in essay films. Since the beginning of the 1990th century the capacity of essay
During the 1950’s and 1960’s an unexplainable phenomenon arose amongst middle class women in North America. Women in the suburbs experienced a feeling of emptiness even though they believed they had everything they could ever ask for in life. This phenomenon is covered by Betty Friedan in The Feminine Mystique (1963) where she discusses the identity crisis and loss of self that many women experien
Today’s marketplace is increasingly growing more competitive as production accelerates and products multiply. Therefore, competing organizations have shifted their focus from solely developing the best product, to building value and competitiveness into the employees. As a result, the concept ‘Employee Engagement’ has received a lot of attention during the 21th century. However there still remain
Background: The relationship between smoking and an increased incidence of cardiovascular diseases is well known. Whether smokeless tobacco (snuff) is related to myocardial infarction (MI) or stroke is still controversial. Aim of this study was to explore whether snuff users have an increased incidence of MI or stroke. Methods: A total of 16 754 women and 10 473 men (aged 45-73 years), without his
Abstract in UndeterminedTranslational stem cell research raises many interesting ethical questions, which have, to a greater or lesser degree, been debated at an international as well as at an interdisciplinary level. Nevertheless, there is still no international consensus regarding how a number of ethical questions related to this research should be answered. Many of these ethical questions creat
OBJECTIVE: We sought to study changes in morphology and stent-graft configuration of descending thoracic aortic aneurysms after endovascular repair. METHODS: Twenty-three patients treated with custom-made stent-grafts were studied. The stent-graft consisted of continuous, stainless-steel Z stents mounted within a polyester graft. In the last 11 cases the stents were interconnected with 3 longitudi
PURPOSE: The purpose of this study was to report an initial experience with the endovascular repair of descending thoracic aortic aneurysm. Complications and intermediate-term morphologic changes were identified with the intent of altering patient selection and device design. METHODS: Endografts were placed into 25 patients at high-risk for conventional surgical repair over a 3(1/2)-year period. D
Mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL) are mature CD5(+) B-cell malignancies with different biological/clinical characteristics. We recently reported an association between different prognostic subgroups of CLL (i.e., IGHV mutated and unmutated) and genomic methylation pattern. However, the relationship between DNA methylation and prognostic markers, such as the prolifer
Vad är en kompetensportfölj? En samling arbetsprover som visar upp den egna kompetensen? En elektronisk plattform för dokumentlagring? En övning i reflektion och utveckling? I denna rapport samlas erfarenheter från medarbetare vid Lunds universitet som under perioden 2015–2016 har arbetat med kompetensportföljer – för studenter och lärare. Rapporten redovisar resultat från tre delprojekt: • Utvec
In this paper, we consider positioning with observed-time-difference-of-arrival (OTDOA) for a device deployed in long-term-evolution (LTE) based narrow-band Internet-of-things (NB-IoT) systems. We propose an iterative expectation- maximization based successive interference cancellation (EM-SIC) algorithm to jointly consider estimations of residual frequency- offset (FO), fading-channel taps and ti
