Search results

cGMP interactors play a role in several pathologies and may be targets for cGMP analog-based drugs, but the success of targeting depends on the biochemical stereospecificity between the cGMP-analog and the interactor. The stereospecificity between general cGMP analogs—or such that are selectivity-modified to obtain, for example, inhibitory actions on a specific target, like the cGMP-dependent prot

Purpose The purpose is to identify, categorise and describe barriers for a fossil-free transport system for urban goods. Design/methodology/approach The barriers are studied from a systems perspective in a case of a mid-sized Nordic city. Data are collected from 15 semi-structured interviews with officials from the city and representatives of private companies, and from policy documents and a work

Early trauma and failures in attachment attunement can affect future relational patterns, health and well-being. The processing of trauma, especially complex trauma, through adequate interventions may help integrate traumatic experiences, enhance health and quality of life. Despite years of clinical practice with Identity oriented psychotrauma therapy (IoPT), there is a lack of scientific research

Purpose: Although business models that deliver sustainability are increasingly popular in the literature, few tools that assist in sustainable business modelling have been identified. This paper investigates how businesses might create balanced social, environmental and economic value through integrating sustainability more fully into the core of their business. A value mapping tool is developed t

Purpose: The article takes its point of departure in the current labor market debate on immigration policy and attempts to explore the way private labor market mediators involved in the integration of immigrants contribute to reproducing cultural stereotypes reminiscent of colonial ideas. Design/methodology/approach: Findings are based on respondent-driven interviews with nine labor market mediato

The ongoing COVID-19 pandemic affects people worldwide. The policies in response to the virus range from closure of national borders to curfews for entire metropolises, like Paris. While we can expect severe impacts on the world economy, the consequences of the pandemic for local sustainability transitions are entirely unclear. In this exploratory study, we investigate how the current situation af

Purpose – This paper will examine the unsafe work practices that are plaguing the construction industry. Statistics show that four out of five of all workplace accidents are attributed to unsafe behaviour. Research studies have sought to understand worker self-protection. For example, it is difficult to make predictions of conditions that influenced worker’s behaviour to act unsafely or safely in

PurposeDoctoral candidates possess specialized knowledge that could support sustainability transitions. Doctoral education, however, often focusses on discipline-specific topics and working methods, making it difficult to “see the bigger picture”. This summer school on wood construction gathered doctoral candidates from different fields to explore how solutions to complex sustainability issues cou

Participation in clinical work is important for medical students’ professional development. However, students often report that they experience a passive observer role, and further research on contextual factors that influence student participation is needed. The theory of practice architectures contributes a new perspective to this challenge by elucidating how cultural-discursive, material-econom

Sharing housing with non-family members has increasingly become a way to reduce costs while pursuing an autonomous yet communal living throughout the life course. During the past decade, a new form of shared housing has entered the Swedish real estate market: coliving. Like shared housing generally, some of the aims of coliving are to help address the housing shortage, decrease loneliness, increas

Purpose: This article aims to illustrate diffractive vignettes as a methodology to extend current communicative and performative approaches. We engage with the critical ethical- onto-epistemological underpinnings of diffraction and explore how it can sensitize communicative research (in particular within the Montréal School (TMS) of CCO scholarship) to processes of materialization - what comes to

The primary objective of this study is to explore and define digital competence from a customer perspective and to examine its impact on an organization's customer-based brand equity. This involves understanding how digital competence influences customer perceptions and contributes to the value of a brand in the digital realm.Design/methodology/approach100 qualitative surveys were conducted to gat

Energy efficiency in industry has been a priority in Chinese policy and planning for more than twenty years. Great achievements in this area have been made. Still, in many cases a considerable potential for improved industrial energy efficiency remains, not least in terms of enhancement of technical capacity. Cement production is one sector where this is evident. Policies have been devised to addr

The ever increasing volume of air transport necessitates new technologies to be adopted by the flight industry to fulfill the requirements of safety, security, affordability, and environmental friendliness while still meeting the growing demand. What we need to achieve this goal is a new type of aircraft cruise control, interconnecting all the onboard active control systems and making more accurat

Purpose - This paper aims to assess the quality of the case study based research approach as documented in articles published during the past 13 years, based on a synthesis of indicators for the quality criteria truth-value, transferability, and traceability. Design/methodology/approach - Content analysis of 134 case study-based articles published in six leading logistics and supply chain manageme

Detection, immobilization and purification of carbohydrates can be done using molecular probes that specifically bind to targeted carbohydrate epitopes. Carbohydrate binding modules (CBMs) are discrete parts of carbohydrate hydrolyzing enzymes that can be engineered to bind and detect specifically a number of carbohydrates. Design and engineering of CBMs has benefited greatly from structural studi

After oesophageal cancer surgery quality of life (QOL) is severely reduced for a long time. Even though this is a well-documented fact no previous studies have focused on the patients' experiences of supportive care after surgery. PURPOSE: To illuminate patients' experiences of supportive care from a long-term perspective after oesophagectomy or oesophagogastrectomy for cancer. METHOD: Data collec