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Risk of complications in patients with conservatively managed ovarian tumours (IOTA5) : a 2-year interim analysis of a multicentre, prospective, cohort study

Background: Ovarian tumours are usually surgically removed because of the presumed risk of complications. Few large prospective studies on long-term follow-up of adnexal masses exist. We aimed to estimate the cumulative incidence of cyst complications and malignancy during the first 2 years of follow-up after adnexal masses have been classified as benign by use of ultrasonography. Methods: In the

Molecular and Structural Biomarkers of Inflammation at Two Years After Acute Anterior Cruciate Ligament Injury Do Not Predict Structural Knee Osteoarthritis at Five Years

Objective: To determine the role of inflammatory biomarkers at 2 years post–anterior cruciate ligament (ACL) injury to predict radiographic knee osteoarthritis (OA) and magnetic resonance imaging (MRI)–defined knee OA at 5 years postinjury, with a secondary aim of estimating the concordance of inflammatory biomarkers assessed by MRI and synovial fluid (SF) analysis. Methods: We studied 113 patient

Cardiometabolic Polygenic Risk Scores and Osteoarthritis Outcomes : A Mendelian Randomization Study Using Data From the Malmö Diet and Cancer Study and the UK Biobank

Objective: To investigate the causal role of cardiometabolic risk factors in osteoarthritis (OA) using associated genetic variants. Methods: We studied 27,691 adults from the Malmö Diet and Cancer Study (MDCS) and replicated novel findings among 376,435 adults from the UK Biobank. Trait-specific polygenic risk scores for low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol

Impact of Human Papillomavirus (HPV)-6/11/16/18 Vaccine on All HPV-Associated Genital Diseases in Young Women.

Background The impact of the prophylactic vaccine against human papillomavirus (HPV) types 6, 11, 16, and 18 (HPV6/11/16/18) on all HPV-associated genital disease was investigated in a population that approximates sexually naive women in that they were "negative to 14 HPV types" and in a mixed population of HPV-exposed and -unexposed women (intention-to-treat group). Methods This analysis studied

Assessment of conventional cardiovascular risk factors and multiple biomarkers for the prediction of incident heart failure and atrial fibrillation.

OBJECTIVES: the purpose of this study was to assess the predictive accuracy of conventional cardiovascular risk factors for incident heart failure and atrial fibrillation, and the added benefit of multiple biomarkers reflecting diverse pathophysiological pathways. BACKGROUND: heart failure and atrial fibrillation are interrelated cardiac diseases associated with substantial morbidity and mortality

Will this hemodynamically unstable patient respond to a bolus of intravenous fluids?

IMPORTANCE Fluid overload occurring as a consequence of overly aggressive fluid resuscitation may adversely affect outcome in hemodynamically unstable critically ill patients. Therefore, following the initial fluid resuscitation, it is important to identify which patients will benefit from further fluid administration. OBJECTIVE To identify predictors of fluid responsiveness in hemodynamically uns

Serum-free retinal explant culture system and comparative rescue effects of LEDGF, GST, CNTF, BDNF, NGF, bFGF and antioxidants in the rd1 mouse model of retinitis pigmentosa

Retinitis pigmentosa is a group of inherited retinal degenerative diseases characterized by the loss of photoreceptors and vision for which no effective treatment is available. Several animal models of retinitis pigmentosa are used to elucidate its pathogenesis and to devise therapies. The retinal degeneration (rd1) mouse is one such animal model in which rod-specific phosphodiesterase (PDE) is in

2016verksamhetsplan

Microsoft Word - 2016Verksamhetsplan.docx Verksamhetsplan - Körcentrum Syd 2016 Inledning Nedanstående verksamhetsplan för år 2016 i Körcentrum Syd har fastställts av Körcentrum Syds styrelse, 2016-02-01. Körcentrum Syd är en centrumbildning inrättad av Lunds Universitet. I Körcentrum Syds styrelse är följande institutioner representerade: Lunds Universitet med Musikhögskolan i Malmö och Odeum, Ma

https://www.korcentrumsyd.lu.se/sites/korcentrumsyd.lu.se/files/2016verksamhetsplan.pdf - 2026-05-20

Policy-brief-2019-final-draft barry ness

Solid Waste Management RECOMMENDATIONS FOR KISUMU, KENYA Mistra Urban Futures Policy Brief 2019:1 Kisumu City generates approximately 400 tonnes of solid waste per day, 20%- 25% of which is collected to the open dump site. Of the total municipal solid waste that is collected, 65% is organic and another 27% is recyclable (County of Kisumu, 2015). The collection and handling of municipal solid waste

https://www.lucsus.lu.se/sites/lucsus.lu.se/files/policy-brief-2019-final-draft_barry_ness.pdf - 2026-05-20

Oseriösa anspråk - när man inte har rätt att få sin talan prövad

One of the basic principles of Swedish law is that everyone is entitled to have his/her claims determined by a court and that the judgment should be given after a hearing. The main rule is that the plaintiff can claim whatever he/she wants, even if it seems absurd. This is a right also given by the European Convention of the human rights article 6:1, which says that everyone is entitled to a publi

A preanalytic validation study of automated bone scan index : Effect on accuracy and reproducibility due to the procedural variabilities in bone scan image acquisition

The effect of the procedural variability in image acquisition on the quantitative assessment of bone scan is unknown. Here, we have developed and performed preanalytical studies to assess the impact of the variability in scanning speed and in vendor-specific γ-camera on reproducibility and accuracy of the automated bone scan index (BSI). Methods: Two separate preanalytical studies were performed:

Caesarean section rates in public vs private hospitals in Europe : a systematic review and meta-analysis using the Robson ten group classification system

INTRODUCTION: Since the last two decades, there has been a dramatic rise in caesarean sections (CS) throughout the world. This increase has been seen even in Europe, where rates vary significantly from 17% in Northern Europe to 56% in the South. Although, CS can be a lifesaving intervention when medically necessary, non-essential CS are associated with short- and long-term complications for both t

Cec syntes no 4 2017

Microsoft Word - CEC Syntes no 4_GA 2 Ekosystembaserad klimatanpassning En kunskapsöversyn CEC SYNTES NR 04 | 2017 | LUNDS UNIVERSITET Centrum för miljö- och klimatforskning Lunds universitet CEC Syntes Nr 04 ISBN 978-91-984349-0-3 Klimatanpassning innebär att vi anpassar våra system och miljöer för att bättre hantera klimatrelaterade risker och skador, samt att på bästa sätt ta tillvara positiva

https://www.cec.lu.se/sites/cec.lu.se/files/cec_syntes_no_4_2017.pdf - 2026-05-20

Verksamhetsberättelse CASE 2020

Nationella forskarskolan om åldrande och hälsa Verksamhetsberättelse 2020 CASE - Centre for Ageing and Supportive Environments Centre for Ageing and Supportive Environments Verksamhetsberättelse 2020 2 Förord Med denna verksamhetsrapport ger vi en kortfattad sammanfattning av den verksamhet som bedrivits inom Centre for Ageing and Supportive Environments (CASE) under 2020. CASE är etablerat som st

https://www.case.lu.se/sites/case.lu.se/files/2021-04/Verksamhetsbera%CC%88ttelse%20CASE%202020.pdf - 2026-05-20

CMES Yearbook 2024 - Webversion compressed

CMES Yearbook 2024 CENTRE FOR ADVANCED MIDDLE EASTERN STUDIES 3CMES YEARBOOK 2024 Table of Contents FROM THE DIRECTOR 5 ABOUT CMES AND THE STRATEGIC RESEARCH AREA MECW 6 CMES RESEARCH PROJECTS 9 CMES RESEARCH SEMINARS 11 CMES PUBLIC LECTURES AND EVENTS 14 POLICY-DIALOGUES, WORKSHOPS, CONFERENCES 18 CMES REGIONAL OUTLOOK 20 TEACHING AND ARABIC STUDIES AT CMES 21 CMES IN MEDIA AND DIGITAL PLATFORMS

https://www.cmes.lu.se/sites/cmes.lu.se/files/2025-05/CMES%20Yearbook%202024%20-%20webversion_compressed.pdf - 2026-05-20

Factors That Affect Disease Progression After First Attack of Acute Pancreatitis

BACKGROUND & AIMS: Little is known about recurrence of pancreatitis after an initial episode, and little is known about how the disease progresses or what factors affect progression. We performed a population-based study of patients with acute pancreatitis (AP) to determine their outcomes and associated factors. METHODS: We performed a retrospective study of patients with first-time AP from 20

A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone-Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation

Sex hormone-binding globulin (SHBG) is a glycoprotein responsible for the transport and biologic availability of sex steroid hormones, primarily testosterone and estradiol. SHBG has been associated with chronic diseases including type 2 diabetes (T2D) and with hormone-sensitive cancers such as breast and prostate cancer. We performed a genome-wide association study (GWAS) meta-analysis of 21,791 i

Intra-aneurysm Sac Pressure in Patients with Unchanged AAA Diameter after EVAR.

OBJECTIVE: To study intra-aneurysm sac pressure and subsequent abdominal aortic aneurysm (AAA) diameter changes in patients without endoleaks that remain unchanged in AAA diameter more than 1 year after endovascular aneurysm repair (EVAR). METHODS: A total of 23 patients underwent direct intra-aneurysm sac pressure (DISP) measurements 16 months (IQR: 14-35 months) after EVAR. Tip-pressure sensors

Long-term infusion of nutrients (total parenteral nutrition) suppresses circulating ghrelin in food-deprived rats.

Background: Ghrelin derives from endocrine cells (A-like cells) in the stomach (mainly the oxyntic mucosa). Its concentration in the circulation increases during fasting and decreases upon re-feeding. This has fostered the notion that the absence of food in the upper gastrointestinal (GI) tract stimulates the secretion of ghrelin. The purpose of the present study was to determine the concentration