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Towards sustainable plastics : Microbial production of aromatic and aliphatic building blocks from biobased feedstock and plastic hydrolysate

The current plastic system is unsustainable and needs to change. Plastics are mainly produced from fossil feedstock, contributing to greenhouse gas emissions, and low rate of post-consumer recycling results in pollution on land and in oceans with high ecological impact, and huge loss of valuable material. There is an urgent need to find solutions for shifting the raw material base to renewable res

Spectroscopic differences in posterior insula in patients with chronic temporomandibular pain

Chronic pain including temporomandibular disorder (TMD) pain involves a complex interplay between peripheral and central sensitization, endogenous modulatory pathways, cortical processing and integration and numerous psychological, behavioral and social factors. The aim of this study was to compare spectroscopic patterns of N-Acetyl-aspartate (NAA), total creatine (tCr), choline (Cho), myo-inosito

Synchrotron X-ray based characterization of technologically relevant III-V surfaces and nanostructures

Populärvetenskaplig sammanfattning:En studie publicerad av NASA:s Goddard Institute for Space Studies år 2019 visade att de genomsnittliga globala temperaturerna under de senaste fyra åren (2015-2018) var de högsta som någonsin registrerats i människans historia. Den nyheten passar väl in i de alarmerande prognoserna om global uppvärmning, och kräver snabba och radikala handlingar. Att studera “teInnovative design and materials are needed to satisfy the demand for efficient and scalable devices for electronic and opto-electronic applications, such as transistors, LEDs, and solar cells. Nanostructured III-V semiconductors are an appealing solution, combining the excellent functional properties of III-V materials with the flexibility typical of nanostructures, such as the nanowires (NWs) stu

Opportunity creation as a mixed embedding process: A study of immigrant entrepreneurs in Sweden

Entrepreneurial opportunities are frequently noted and addressed in the literature of immigrant entrepreneurship; however, little is known about how these entrepreneurial opportunities come into existence and how immigrant entrepreneurs create such opportunities. The purpose of this thesis is to examine why and how immigrant entrepreneurs create entrepreneurial opportunities through embedding proc

Rivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial

Background: Patent foramen ovale (PFO) is a contributor to embolic stroke of undetermined source (ESUS). Subgroup analyses from previous studies suggest that anticoagulation could reduce recurrent stroke compared with antiplatelet therapy. We hypothesised that anticoagulant treatment with rivaroxaban, an oral factor Xa inhibitor, would reduce the risk of recurrent ischaemic stroke compared with as

Child and Adolescent Health From 1990 to 2015 : Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2015 Study

Importance: Comprehensive and timely monitoring of disease burden in all age groups, including children and adolescents, is essential for improving population health.Objective: To quantify and describe levels and trends of mortality and nonfatal health outcomes among children and adolescents from 1990 to 2015 to provide a framework for policy discussion.Evidence Review: Cause-specific mortality an

Global, regional, and national burden of neurological disorders during 1990-2015 : a systematic analysis for the Global Burden of Disease Study 2015

BACKGROUND: Comparable data on the global and country-specific burden of neurological disorders and their trends are crucial for health-care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study provides such information but does not routinely aggregate results that are of interest to clinicians specialising in neurological conditions. In this syst

Some Physical and Environmental Aspects of Shallow Ice Covered Lakes : Emphasis on Lake Vendyurskoe, Karelia, Russia.

The ice cover presence on the surface of a lake insulates the water body from the atmosphere. This prevents or reduces the influence of processes which depend on the exchange between the atmosphere and the water surface. This implies significant reduction or elimination of some processes taking place at the open water surface; for instance, a substantial reduction in solar energy penetrating to th

Effectiveness of Internet-Based Exercises Aimed at Treating Knee Osteoarthritis : The iBEAT-OA Randomized Clinical Trial

Importance: Osteoarthritis is a prevalent, debilitating, and costly chronic disease for which recommended first-line treatment is underused.Objective: To compare the effect of an internet-based treatment for knee osteoarthritis vs routine self-management (ie, usual care).Design, Setting, and Participants: This randomized clinical trial was conducted from October 2018 to March 2020. Participants in

Towards sustainable water use in industry: a case study of the oil refinery industry in Kazakhstan

The concept of “Sustainable water use” (SWU) aims to assure three pillars of sustainability related to the water sector: the social, environmental, and economical. Industrial development, especially in developing countries, requires an adequate response, as industrial activities are recognized as one of the major sources of water pollution, what leads to deterioration of environmental safety and w

Structural and Functional Analyses of Xyloside-primed Glycosaminoglycans

Glycosaminoglycans (GAGs) are polysaccharides produced by essentially all mammalian cells. Due to their enormous structural diversity, they are involved in many biological processes both in health and disease, including all stages of tumor progression. GAGs are normally attached to a core protein as a part of a proteoglycan; however, GAG biosynthesis can be induced by compounds composed of a xylos

Evaluation of physical work capacity and leg muscle fatigue during exhaustive stair ascending evacuation

AbstractPhysical exhaustion can constrain human ascending work capacity and performance during emergency evacuation on stairs. The overall aim of this research was to explore and compare stair ascending capacities and physiological limitations during two different strategies: self-preferred pace in three different public stairways in the field, and controlled pace in a laboratory on a stair machin

Comparative analysis of the understanding of 'expertise' and 'resilience' in novice and expert anesthesiologists

Anesthesiology is the medical specialty dedicated to the relief of pain and care of the surgical patient before, during and after surgery. Most of the work in anesthesiology is routine patient care, but because patients are sick and surgical procedures may develop in unexpected ways, anesthesiology by its nature often involves medical crises. In recent years, two concepts have gained increasing i

Feasibility of adaptive SBRT of prostate cancer: Investigating uncertainties in AI-driven and CBCT-guided online adaptive radiotherapy

Cancer kan drabba vem som helst och kan ha sitt ursprung i många olika områden i kroppen. Antalet nya cancerfall ökar varje år, men vissa typer av cancer har bättre prognos än andra. Den vanligaste cancertypen i Sverige är prostatacancer och den drabbar framför allt äldre män. Prostatacancer har god prognos och det finns effektiva metoder att helt bota prostat- acancer om den behandlas i ett tidigPurpose: Recent developments in external radiotherapy and its utilization with artificial in- telligence (AI) enables advanced treatment plans for a range of different disease sites. By adapting to the anatomy of the day, target coverage can be ensured while sparing more healthy tissue. The purpose of this project was to study the feasibility and benefits of daily cone beam computed tomography (CB

Optimization of aftermarket logistics with dual supply chains for Sandvik AB

Background: Aftermarket logistics is important for a manufacturing company to maintain customer satisfaction in the long run. However, the supply chain set for aftermarket parts is equally crucial as the original equipment. Modification or optimization of the logistics systems for slow-moving aftermarket items is inevitable. Sandvik, an engineering company in the mining industry is now interested

The Economization of Migration

Being acquainted with four of the most famous games in game theory, we will learn that players often are better paid off cooperating with each other, but that the structure of the game forces them to defect from cooperation. Only when confronted with the zero-sum game the players have no incentive to cooperate. In all the other games, cooperation is secured if the players commit themselves to adop

Swedish State Monopolies and their Compatibility with EC Law

The principal rule of the common market is that goods and services are able to move freely across the borders of Member States. State monopolies in control of supply and demand are, therefore, only under exceptional circumstances compatible with the conditions of the common market. The compatibility of Swedish State monopolies with EC law is a controversial matter. The case-law of the ECJ lets us

Investigating CSF flow in patients with idiopathic normal pressure hydrocephalus using phase-contrast 7T MRI

Idiopatisk normaltryckshydrocephalus (iNPH) är en neurologisk sjukdom som påverkar hjärnans vätskecirkulation och kan leda till symtom som gång- och balanssvårigheter, kognitiv nedsättning och urininkontinens. Sjukdomen drabbar omkring 1.5 % av 70-åringar, och prevalensen ökar med åldern. Det är en svårdiagnostiserad sjukdom där hjärnvätska (CSF) ansamlas i hjärnans hålrum, vilket påverkar hjärnanIntroduction: Idiopathic normal pressure hydrocephalus (iNPH) is a treatable but largely underdiagnosed neurological condition affecting the elderly population. It is characterised by gait and cognitive impairment, as well as urinary incontinence. For the most part, it is diagnosed via imaging and clinical assessments. Abnormalities in cerebrospinal (CSF) flow in the cerebral aqueduct have been li

Monte Carlo Simulation for the detection of intracranial hematoma using near-infrared light

Monte Carlo simulation is a numerical method that can simulate complex physical systems and is widely used in the field of medical optics. For example, the Monte Carlo method was used to evaluate the effectiveness of near-infrared spectroscopy (NIRS) in the detection of intracranial hematoma (ICH). However, due to the relatively complex brain structure, the current simulation model is relatively s

Comparison of plasma ALZpath p-Tau217 with Lilly p-Tau217 and p-Tau181 in a neuropathological cohort

There is an urgent need for accurate and validated methods to measure plasma phosphorylated tau (p-Tau) biomarkers in Alzheimer’s disease (AD). In this study, we compared the performance of new commercially available plasma p-Tau217 assay developed by ALZpath to other established p-Tau assays in an autopsy-confirmed sample. We included 72 participants from the Arizona Study of Aging and Neurodegen