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OBJECTIVE: Periodontal ligament (PDL) cells express oestrogen receptor beta (ERbeta) protein, but cellular functions regulated by ERbeta in these cells have not been identified. In this study we determine if ERbeta is localised to mitochondria and if oestrogen regulates mitochondrial function in human PDL cells obtained from teeth extracted for orthodontic reasons. DESIGN: Subcellular distribution

Background: The use of life stories in dementia care has been described as a way of seeing every person as an individual, looking beyond their dementia. Life stories have become synonymous with high-quality care, while in Sweden their mere existence in dementia care settings is taken to indicate quality in national comparisons. Such life stories are often standardised, generated by a family member

INTRODUCTION: Acute kidney injury (AKI) is a common problem in hospitalized patients, requiring extensive treatment and carries a high mortality rate. This study was designed to assess the epidemiology of AKI, and risk factors and outcome of patients with severe AKI in a tertiary care university hospital in Iceland.MATERIAL AND METHODS: All adult patients with measured serum creatinine (SCr) in La

Objective: To assess the cross-sectional association between meniscal status and joint effusion on magnetic resonance imaging (MRI) in knees without radiographic osteoarthritis (OA). Design: Knees without OA (Kellgren/Lawrence grade 0) from the Framingham and MOST studies were examined by MRI. Meniscal status was assessed with a score of 0-4 in the anterior horn/body/posterior horn of the medial/l

BACKGROUND: Cannabinoid (CB) receptors may be involved in the control of bladder function; the role of CB receptor subtypes in micturition has not been established. OBJECTIVES: Our aim was to evaluate the effects of cannabinor, a novel CB2 receptor agonist, on rat bladder function. DESIGN, SETTING, AND PARTICIPANTS: Sprague Dawley rats were used. Distribution of CB2 receptors in sensory and cholin

Abstract Objectives. Pulmonary hypertension (PH) due to left heart disease may impair outcome after heart transplantation (HT). To evaluate to what extent previous, and present, haemodynamic criteria discriminate the impact of pre-operative-PH on survival, we characterized the PH in our HT-patients according to ESC's guidelines, ISHLT's summary statement and ISHLT's relative contraindications and

Objective: To review the Anorectal Malformation Network experience with perineal groove (PG) focusing on its clinical characteristics and management. Study design: Data on patients with PG managed at 10 participating Anorectal Malformation Network centers in 1999-2019 were collected retrospectively by questionnaire. Results: The cohort included 66 patients (65 females) of median age 1.4 months at

Diffuse nitrate pollution remains a persistent threat to drinking-water resources, yet current predictive frameworks rarely capture how the spatial composition (land-cover fractions) and configuration (landscape fragmentation) of land systems jointly modulate leaching. This study presents a novel multiscale framework integrating hydro-climatic, soil and anthropogenic predictors with land-cover fra

Strut-based structures, such as lattices, produced using additive manufacturing (AM) offer significant potential for applications requiring lightweighting and structural compliance. However, conventional Design for AM (DfAM) approaches often assume idealised material behaviour, which can be misleading for thin strut-based structures where geometric parameters and process-induced effects significan

Structured Abstract Background Sexual health and functioning are significant, yet often overlooked, components of psychosocial well-being of adults with congenital heart disease (ACHD). Prior research reports inconsistent findings, limited data on older adults with CHD, and few studies have compared patients with controls from the general population. This study investigated sexual functioning in m

Year In Brief 2020 Lund University Innovation Year in Brief 2020 From ideas to innovations With cross-disciplinary and cutting- edge research, Lund University represents a tremendous source of know-how and knowledge and has become a hub for innovations and new ways of thinking. At LU Innovation, we strive to create the best preconditions for the students and researchers in their pursuit to achieve

https://www.innovation.lu.se/sites/innovation.lu.se/files/2021-02/LU-Inn_YIB_2020_v2.pdf - 2026-05-28

GUN Protkoll 2020-09-17 Sida 1 av 9 GUN PROTOKOLL Diarienummer Biologiska institutionen Datum 2020-09-17 Protokoll Grundutbildningsnämnden GUN Närvaro Närvarande ledamöter Jep Agrell ordförande, huvudstudierektor, Jan-Åke Nilsson koordinator för mastersprogrammet i biologi, Klas Flärdh koordinator för mastersprogrammet i molekylärbiologi, Dag Ahrén koordinator för mastersprogrammet i bioinformatik

https://www.biologi.lu.se/internt/sites/biologi.lu.se.internt/files/2020-12/GUNProtkoll20200917.pdf - 2026-05-28

OBJECTIVES:: To investigate the association between adverse events recorded during critical care and mortality in out-of-hospital cardiac arrest patients treated with therapeutic hypothermia. DESIGN:: Prospective, observational, registry-based study. SETTING:: Twenty-two hospitals in Europe and the United States. PATIENTS:: Between October 2004 and October 2008, 765 patients were included. INTERVE

OBJECTIVE: Free radicals formed after coronary artery occlusion and reperfusion are assumed to produce myocardial stunning and possibly other forms of reperfusion injury as well. Malondialdehyde (MDA) is an end product in the lipid peroxidation chain reaction and is frequently used as a marker for free oxygen radical production. Increased levels of plasma MDA have been found following successful t

BACKGROUND: Data from several studies support the hypothesis that thrombopoietin (TPO) plasma levels are regulated via circulating platelet (PLT) numbers by binding to PLT TPO receptors (TPO-Rs). In this study, PLT numbers and TPO plasma levels were measured following the transfusion of unmanipulated, sham-saturated, and TPO-R-saturated PLT preparations to provide additional in vivo evidence for t

Objective: To describe anthropometric characteristics of participants of the European Prospective Investigation into Cancer and Nutrition (EPIC). Design: A cross-sectional analysis of baseline data of a European prospective cohort study. Subjects: This analysis includes study populations from 25 centres in nine European countries. The British populations comprised both a population-based and a 'he

OBJECTIVES: To estimate the total direct medical costs to society for patients with type 2 diabetes in Sweden and to investigate how different factors, for example diabetic late complications, affect costs. DESIGN: Cross-sectional data regarding health care utilization, clinical characteristics and quality of life, were collected at a single time-point. Data on resource use cover the 6-month perio

Popular Abstract in Swedish Inför hjärtkirurgi är bedömning av en patients individuella nytta av och risk vid en hjärtoperation en viktig komponent i utredningen inför operationen. En riskstratifiering innebär att patientens olika riskfaktorer (exempelvis sockersjuka, högt blodtryck, antal tidigare hjärtinfarkter, hjärtfunktion) vägs samman till en sannolikhets-bedömning av risken för en viss händThe aims of this research was to compare different risk score algorithms with regard to their validity to predict 30-day and one-year mortality after open-heart surgery, to evaluate if the preoperative risk stratification model EuroSCORE predicts the different components of resource utilization in cardiac surgery, and to systematically evaluate the accuracy and performance of artificial neural net

The Children’s Revised Impact of Event Scale (CRIES) is a brief child-friendly measure designed to screen children at risk for Posttraumatic Stress Disorder (PTSD). It has good face and construct validity, a stable factor structure, correlates well with other indices of distress, and has been used to screen very large samples of at-risk-children following a wide range of traumatic events. However,