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Background: The role of antioxidants in the pathogenesis of type 2 diabetes is uncertain. Objective: We evaluated cross-sectional relations of dietary intakes and plasma concentrations of antioxidants with glucose metabolism in a high-risk population. Design: The subjects, were 81 male and 101 female first- and second-degree, nondiabetic relatives of patients with type 2 diabetes. Antioxidant inta

BACKGROUND: Current clinical assessments of motor function in Huntington's Disease (HD) rely on subjective ratings such as the Unified Huntington's Disease Rating scale (UHDRS). The ability to track disease progression using simple, objective, inexpensive, and robust measures would be beneficial.METHODS: One objective measure of motor performance is hand-tapping. Over the last 14 years we have rou

PURPOSE: To evaluate the plasma level of different forms of soluble urokinase plasminogen activator receptor (suPAR) as discriminators between malignant, borderline, and benign ovarian tumors and as prognostic markers in patients with ovarian cancer. EXPERIMENTAL DESIGN: The different suPAR forms were measured in preoperative plasma samples obtained from 335 patients with adnexal lesions using thr

Miljömässiga vinster genom konstruktions- & materialtekniska lösningar -betong Byggindustrin står idag för 20 % av Sveriges inhemska utsläpp av växthusgaser. För konstruktörer och andra aktörer i branschen finns det idag få incitament att försöka minska användningen av cement, vars produktion är en av de största källorna till utsläpp från byggsektorn. Detta examensarbete undersöker några olikThe greenhouse effect and the emission of greenhouse gases, namely carbon dioxide, is a global issue which today permeates alot of the societal consciousness and therefore also alot of the conducted research. The construction industry is not different in this regard. The construction sector in Sweden, for example, generates more than 12 million metric tonnes of carbon dioxide equivalents every yea

Transporten i och genom de biologiska membranerna är väldigt viktig och har många applikationer i mat- och läkemedel industrier. Dessa membranerna består av dubbel-lager av lipid molekyler. Genom att blanda två olika sorter av lipiderna diglycerolmonooleate (DGMO) och glycerol monooleate (GMO-50) med nano-partikelstabilisatorpolysorbate 80 (P80) i överskott av vatten skapar det en lipidblandning mTransport in and through biological membranes that consist of lipid bilayers has a crucial role in many applications in the food or pharmaceutical industries. How to deliver an enzyme through the membranes without damaging the enzymatic activity or the "shelf-life" of the enzyme has been of large interest since 1970 [29-30]. In this work, we have shown that a thin lipid sponge phase (L3)

Purpose: The purpose of this study is to explore how brand managers align their brand identity within online brand communities where the communication is shared in order to create a reinforcing point of contact instead of a source of mixed messages. Problem: With the increasing usage of the internet, brand managers are today forced and challenged to align and re-enforce a brand’s identity online w

Title: Understanding Perceptions and Usage of Social Media in the Context of Relationship Building: A Generational Comparison Date of the Seminar: 30 May 2012 Course:BUSN29. Master Thesis Authors:Lovisa Haglind and Caroline Jonsson Advisor: Jon Bertilsson Keywords: Generations, Social Media and Relationship Building Thesis purpose: The purpose of this study is to examine on what basis diverse gene

OBJECTIVE Over 30 loci have been associated with risk of type 2 diabetes at genome-wide statistical significance. Genetic risk scores (GRSs) developed from these loci predict diabetes in the general population. We tested if a GRS based on an updated list of 34 type 2 diabetes-associated loci predicted progression to diabetes or regression toward normal glucose regulation (NGR) in the Diabetes Prev

The importance of carbohydrates in biological systems has become evident during the last fifty years. It is well known that pathogenic bacteria and viruses attach to glycoconjugates present at mammalian cell surfaces, and that this attachment is a prerequisite for the later stages of infection. Obviously, this interaction is interesting as a target for the development of novel ways to treat bacter

In the thesis, three-dimensionally confined resonant tunneling structures were studied experimentally. Two approaches were used for obtaining quantum confinement: gate-defined lateral constriction of double barrier structures, and epitaxial growth of self-assembled quantum dots. In addition, the thesis deals with the basic development of large-area double barrier resonant tunneling diodes, as a st

Background We aimed to estimate lifetime cumulative risk of thyroid cancer (CRTC) in first-degree relatives of patients with non-medullary thyroid cancers (NMTC), including papillary (PTC)/follicular/oxyphilic/anaplastic thyroid carcinoma, by histology and age at diagnosis in patients and their relatives. Design A population-based cohort of 63 495 first-degree relatives of 11 206 NMTC patients dia

Objective To investigate the prevalence of and factors associated with overactive bladder in middle-aged women. Design Cross sectional population-based study. Setting Southern Sweden and the Women's Health in the Lund Area study (WHILA 1995-2000) where 6917 (64% of the invited) women, 50-59 years old in 1995, participated. Population From the WHILA study, 1500 women reporting troublesome urinar

Objective. To study to what extent geographical differences of the mortality from ischaemic heart disease (IHD) can be accounted for by the 28-day case fatality rate (CFR) following first hospital admittance for acute myocardial infarction (MI) and whether the geographical pattern of survival has any relationship with socio-economic circumstances. Design. Register-based surveillance study. Setting

Objectives: To examine if obesity status and socio-economic and lifestyle factors are associated with self-reported past food habit change, and also whether the level of obesity depends on the reason for change. Design: Cross-sectional analysis within the Malmo Diet and Cancer (MDC) study using data from the baseline examination and the extensive socio-economic and lifestyle questionnaire includin

Objective: Prospectively monitor how treatment of acutely ruptured anterior cruciate ligament (ACL) affects biomarkers of inflammation and proteolytic degradation over 5 years. Design: We studied 119 subjects with acute ACL injury from the randomized controlled knee anterior cruciate ligament, non-surgical versus surgical treatment (KANON)-trial (Clinical trial ISRCTN 84752559) who had synovial fl

In this paper, we consider positioning with observed-time-difference-of-arrival (OTDOA) for a device deployed in long-term-evolution (LTE) based narrow-band Internet-of-things (NB-IoT) systems. We propose an iterative expectation- maximization based successive interference cancellation (EM-SIC) algorithm to jointly consider estimations of residual frequency- offset (FO), fading-channel taps and ti

The European X-ray Free Electron Laser (XFEL) will deliver 30,000 fully coherent, high brilliance X-ray pulses per second each with a duration below 100 fs. This will allow the recording of diffraction patterns of single complex molecules and the study of ultra-fast processes. Silicon pixel sensors will be used to record the diffraction images. In 3 years of operation the sensors will be exposed t

Objective: To investigate the relationship between meniscus magnetic resonance (MR) relaxation parameters and meniscus degradation through quantitative imaging of ex vivo posterior horns of menisci from subjects with and without knee osteoarthritis (OA). Design: We sampled medial and lateral menisci from ten medial compartment knee OA patients (mean age 63 years) undergoing total knee replacement

OBJECTIVE: Trans-catheter (TC) pulmonary valve replacement (PVR) has become common practice for patients with right ventricular outflow tract obstruction (RVOTO) and/or pulmonic insufficiency (PI). Our aim was to compare PVR and right ventricular (RV) function of patients who received TC vs surgical PVR.DESIGN: Retrospective review of echocardiograms obtained at three time points: before, immediat

Context: The gut hormone neurotensin promotes fat absorption, diet-induced weight gain, and liver steatosis. Its stable precursor-hormone fragment "proneurotensin" predicts cardiometabolic disease in middle-aged populations, especially in women. Objective: To test if proneurotensin predicts cardiovascular disease (CVD) and diabetes development in an elderly population and whether there are gender