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Evaluation of Circulating Cardiovascular Biomarker Levels for Early Detection of Congenital Heart Disease in Newborns in Sweden

Importance: Congenital heart disease (CHD) is the most common congenital malformation in humans worldwide. Circulating cardiovascular biomarkers could potentially improve the early detection of CHD, even in asymptomatic newborns. Objectives: To assess the performance of a dried blood spot (DBS) test to measure the cardiovascular biomarker amino terminal fragment of the prohormone brain-type natriu

The generative principles of lifestyle enterprising : dialectic entanglements of capital-habitus-field

Purpose: The study seeks to shed light on the generative principles of enterprising by examining the practices of enterprisers in six lifestyle enterprises in Sweden. It presents a fresh approach to the study of lifestyle enterprises, resolving a nuanced treatment of the concepts of capital and habitus as often drawn upon in studies using the social theory of Pierre Bourdieu. Design/methodology/ap

Prostate Cancer Death After Radiotherapy or Radical Prostatectomy : A Nationwide Population-based Observational Study

Background: There are no conclusive results from randomized trials on radiotherapy (RT) versus radical prostatectomy (RP) for prostate cancer. Numerous observational studies have suggested that RP is associated with a lower risk of prostate cancer death, but whether results have been biased due to limited adjustments for confounding factors is unknown. Objective: To compare the risk of prostate ca

Från fotsteg till bevisfakta - En analys av rörelsedata från hälsoapplikationer som bevis i brottmål

Denna uppsats undersöker hur rörelsedata från hälsoapplikationer presenteras och värderas som bevis i svenska brottmål samt vilka rättssäkerhetsmässiga utmaningar som är förknippade med denna typ av digital bevisning. Uppsatsen inleds med en genomgång av de processrättsliga ramar som styr bevisprövningen i brottmål, med särskilt fokus på principen om fri bevisprövning. Därefter presenteras rörelseThis thesis examines how motion data from health applications is presented and evaluated as evidence in Swedish criminal trials, as well as the legal safeguards and challenges associated with this type of digital evidence. It begins with an overview of the procedural rules governing the assessment of evidence in criminal proceedings, with particular focus on the principle of free evaluation of evi

Interoperability in EU Competition Law: Rethinking the Essential Facilities Doctrine for Digital Platforms after Android Auto

Denna uppsats undersöker hur EU:s konkurrenslagstiftning reglerar interoperabilitetsskyldigheter för dominerande digitala plattformar. Uppsatsen visar hur EU-domstolens avgörande i Android Auto (C-233/23) omformar teorin om nödvändiga nyttigheter (Essential Facilities Doctrine, EFD) som etablerades i Bronner-domen (C-7/97). Vidare analyseras denna framväxande doktrins samspel med de interoperabiliThis thesis explores how EU competition law governs interoperability obligations for dominant digital platforms. It shows how the CJEU’s judgment in Android Auto (C-233/23) redefines the Essential Facilities Doctrine (EFD) established in Bronner judgment (C-7/97) and how this emerging doctrine interacts with the interoperability obligations introduced by the Digital Markets Act (DMA). The Android

Global Disparities in Premature Mortality

Importance: Persistent disparities in mortality across countries suggest uneven improvements in living standards and access to life-extending health technologies, as well as context-specific obstacles. Studies have analyzed cross-country inequality in mortality but have not widely contextualized those disparities in terms of developmental progress relative to a frontier representing a level of mor

Development of a membrane filtration process for concentrating a fava bean extract for plant-based dairy applications

Introduction:Fava beans are becoming an increasingly popular and viable crop, offering a nutritious option for innovative plant-based food products. Despite their potential, fava beans remain underutilized in the food industry, with their primary use still being as animal feed [1]. However, fava beans are an interesting base material for producing plant-based milk alternatives. While soy milk curr

Anpassningsskyldighet för tillhandahållare av nummeroberoende interpersonella kommunikationstjänster - En utredning av vilka konsekvenser en anpassningsskyldighet för tillhandahållare av allmänt tillgängliga Noik kan medföra ur ett integritetsperspektiv.

Den organiserade brottsligheten i Sverige går som på ett löpande band i stigande riktning. Brottsbekämpande myndigheter gör vad de kan för att motverka denna utveckling men det blir allt svårare att hålla hårt i tyglarna. I ett försök att underlätta dessa myndigheters arbete beslutade regeringen den 5 augusti 2021 att tillsätta en särskild utredning med uppdrag att se över den lagstiftning som åOrganized crime in Sweden is on a continuous upward trend. Law enforcement authorities are doing what they can to counteract this development, but it is becoming increasingly difficult to maintain control. In an attempt to facilitate the work of these authorities, the Government decided on August 5, 2021, to appoint a special inquiry tasked with reviewing the legislation that obliges providers of

Development of a membrane process for the concentration of fava bean extract for plant-based dairy applications

Introduction. Fava beans are an increasingly popular and viable crop, and an excellent nutritious choice for novel plant-based food products. Fava beans are industrially underexploited as a food ingredient and are today mainly used as animal feed [1]. However, fava beans are an interesting base material for producing plant-based milk. While soy milk dominates the legume-based beverage segment, the

Number of risk factors versus infection after transrectal prostate biopsy : a nationwide population-based study

OBJECTIVE: It is unknown how risk factors for infection after transrectal prostate biopsy interact. We designed a study to evaluate this.METHODS: We identified biopsy procedures from 2006 to 2020 in the Swedish nationwide database PCBaSe. Primary outcome was post-biopsy infection, defined as a dispensed prescription of a urinary tract antibiotic and secondary outcome was inpatient care for infecti

A High-Throughput Method for Screening for Genes Controlling Bacterial Conjugation of Antibiotic Resistance

The rapid horizontal transmission of antibiotic resistance genes on conjugative plasmids between bacterial host cells is a major cause of the accelerating antibiotic resistance crisis. There are currently no experimental platforms for fast and cost-efficient screening of genetic effects on antibiotic resistance transmission by conjugation, which prevents understanding and targeting conjugation. We

Placement of an intrauterine device within 48 hours after second-trimester medical abortion : a randomized controlled trial

Background: International guidelines recommend placement of intrauterine devices immediately after second-trimester medical abortion, but evidence concerning the optimal time for intrauterine device placement is lacking from clinical trials. Objective: This study aimed to investigate effectiveness, safety, and acceptability of intrauterine device placement within 48 hours, compared with placement

Charles Bonnet Syndrome Adversely Affects Vision-Related Quality of Life in Patients with Glaucoma

Purpose: To investigate the impact of Charles Bonnet syndrome (CBS) on vision-related quality of life (VRQoL) in patients with glaucoma. Design: Cross-sectional cohort study. Participants: Twenty-four patients with CBS and 42 matched controls without CBS out of 337 patients with open-angle glaucoma (OAG) with visual field (VF) loss. Methods: A matching technique was used to identify control patien

Correlation between maternal and umbilical cord 25-hydroxy-vitamin D levels over a range of values. A prospective observational study from the United Arab Emirates

Worldwide vitamin D insufficiency is remarkably prevalent in both children and adults, including pregnant women. The total amount of the vitamin is best measured by 25-hydroxy-vitamin D (25(OH)D), which is a measurement of total serum cholecalciferol 25 (OH)D3 and ergocalciferol 25(OH)D2. There is a known correlation between maternal and umbilical cord blood (UCB) 25(OH)D; however, whether specifi

Accelerometer derived physical activity and subclinical coronary and carotid atherosclerosis : cross-sectional analyses in 22 703 middle-aged men and women in the SCAPIS study

OBJECTIVES: The aim included investigation of the associations between sedentary (SED), low-intensity physical activity (LIPA), moderate-to-vigorous intensity PA (MVPA) and the prevalence of subclinical atherosclerosis in both coronaries and carotids and the estimated difference in prevalence by theoretical reallocation of time in different PA behaviours.DESIGN: Cross-sectional.SETTING: Multisite

Cumulative live birth rate after IVF : Trend over time and the impact of blastocyst culture and vitrification

STUDY QUESTION: Has cumulative live birth rate (CLBR) improved over time and which factors are associated with such an improvement? SUMMARY ANSWER: During an 11-year period, 2007-2017, CLBR per oocyte aspiration increased significantly, from 27.0% to 36.3%, in parallel with an increase in blastocyst transfer and cryopreservation by vitrification. WHAT IS KNOWN ALREADY: While it has been shown that

Dynamic Shear Rheometer for rheological investigation of bitumen in road applications : The impact of measurement technique

The rheological properties of bituminous binders tested with a dynamic shear rheometer (DSR) as a function of loading time and temperature can more accurately represent real road situations with rising traffic loads and densities combined with climatic change. This method is more effective than traditional methods such as measuring the softening point and penetration. Complex shear modulus and pha

Digital municipal currencies as a policy instrument for counter-politics : The case of the State of Rio de Janeiro

At the onset of the pandemic, Brazil’s Federal government approved an emergency basic income to be transferred to a variety of groups that had not earlier received any of the established welfare programs. Its implementation was however riddled with challenges. With a large informal economy, many Brazilian citizens were missing from the Federal Government’s registry and, even if registered, many di

Everything has its processes, one could say. A longitudinal study following students' ideas about transformations of matter from age 7 to 16

This thesis concerns students’ learning and meaning-making in science. The theoretical framework builds upon Human Constructivism. This perspective underlines the unique interplay that occurs between thinking, feeling, and acting in human meaning-making and also stresses the important role of language in learning proc-esses. The aim of the thesis is to learn more about how individual students deve

Vibrations in a Built Environment : Prediction and Reduction

Vibrations in a built environment can exceed the requirements for sensitive equipment in a building or can cause annoyance to residents. Hence, there is often a need for reducing such vibrations. The vibrations can originate from ambient sources such as motorway traffic, or from internal sources such as people walking inside the building. Disturbing vibrations can be reduced by reduction measures.