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A correlation for predicting smoke layer temperature in a room adjacent to a room involved in a pre-flashover fire

Advanced fire modelling software have been developed and improved during the last couple of decays and thesekinds of software have been shown to be valuable tools for fire safety engineers. However, the advances made have not replaced the need for simple hand-calculation methods. Simple hand-calculations methods can be used to obtain a first estimate of, for example, smoke layer temperatures in a per

ICOS-ligand triggering impairs osteoclast differentiation and function in vitro and in vivo

Osteoblasts, osteocytes, and osteoclasts (OCs) are involved in the bone production and resorption, which are crucial in bone homeostasis. OC hyperactivation plays a role in the exaggerated bone resorption of diseases such as osteoporosis, rheumatoid arthritis, and osteolytic tumor metastases. This work stems from the finding that OCs can express B7h (ICOS-Ligand), which is the ligand of the ICOS T