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Purpose: Monte Carlo (MC) modelling techniques can assess the quantitative accuracy of both planar and SPECT Nuclear Medicine images. It is essential to validate the MC code's capabilities in modelling a specific clinical gamma camera, for radionuclides of interest, before its use as a clinical image simulator. This study aimed to determine if the SIMIND MC code accurately simulates emission image
We generated human iPS derived neural stem cells and differentiated cells from healthy control individuals and an individual with autism spectrum disorder carrying bi-allelic NRXN1-alpha deletion. We investigated the expression of NRXN1-alpha during neural induction and neural differentiation and observed a pivotal role for NRXN1-alpha during early neural induction and neuronal differentiation. Si
Background: The inverse observational association between body mass index (BMI) and lung cancer risk remains unclear. We assessed whether the association is explained by metabolic aberrations, residual confounding, and within-person variability in smoking, and compared against other smoking-related cancers. Methods: We investigated the association between BMI, and its combination with a metabolic
Accumulating evidence suggests that gestational exposure to endocrine disrupting chemicals (EDCs) may interfere with normal brain development and predispose for later dysfunctions. The current study focuses on the exposure impact of mixtures of EDCs that better mimics the real-life situation. We herein describe a mixture of phthalates, pesticides and bisphenol A (mixture N1) detected in pregnant w
BACKGROUND: A substantial proportion of cancer driver genes (CDG) are also cancer predisposition genes. However, the associations between genetic variants in lung CDGs and the susceptibility to lung cancer have rarely been investigated. METHODS: We selected expression-related single-nucleotide polymorphisms (eSNP) and nonsynonymous variants of lung CDGs, and tested their associations with lung can
OBJECTIVE: To investigate the association of plasma vitamin C and carotenoids, as indicators of fruit and vegetable intake, with the risk of type 2 diabetes. DESIGN: Prospective case-cohort study. SETTING: Populations from eight European countries. PARTICIPANTS: 9754 participants with incident type 2 diabetes, and a subcohort of 13 662 individuals from the European Prospective Investigation into C
Otillåten andrahandsuthyrning och oskäliga andrahandshyror är ett omfattande problem i Sverige. Förstahandshyresgäster upplåter sina lägenheter utan tillstånd och tar ut alldeles för höga hyror. Problemet har uppmärksammats av Justitiedepartementet, som i februari 2017 tillsatte en utredningskommitté med uppdraget att se över om gällande hyreslagstiftning kräver ändringar för att motverka uttag avUnlawful subletting and unjustifiable rents are widespread problems in Sweden. Tenants sublet their rental apartments without landlords’ permission and charge subtenants too high rental levels. The issue has drawn the attention of the Swedish Ministry of Justice, which in February 2017 appointed a committee to investigate whether decreasing unlawful subletting motivated by lucrative profits requir
I 23 kap. 6 § 1 st. BrB stadgas straffansvar för den som underlåter att i tid avslöja ett förestående eller pågående brott. Skyldigheten att avslöja brott gäller vissa utvalda allvarliga brott, som exempelvis mord, mordbrand och våldtäkt. Bestämmelsen används sällan i rättspraxis och det saknas för närvarande något prejudicerande avgörande gällande hur underlåtenhet att avslöja brott ska tillämpasFailure to reveal a crime is criminalized in Chapter 23, Section 6, first paragraph of The Swedish Penal Code. The obligation to reveal a crime does only apply to a few serious crimes, such as murder, arson and rape. Currently, a valid precedent from the supreme court regarding the interpretation of the provision does not exist. The provision is rarely applied by the courts of law. A possible expl
Shopping for second-hand clothes is a phenomenon that has been on the rise, especially for the last twenty years. Second-hand clothes (SHC) consumption is a consumer-generated shopping trend whose consumers are discursively creating new identity meaning(s) for themselves out of their consumption. It has changed the outlook to become a fashionable trend in the last 20 years and is positively influe
Halligen are small low-lying islands that only exist in the North Sea and get flooded during storm surges. The North Sea’s Sea level is projected to rise 60 to 70cm by 2100, making climate change adaptation a question of survival for the Hallig residents. Previous research has focused on technical aspects of adaptation, leaving a knowledge gap on how power and public participation shape adaptation
Current food consumption habits in wealthy countries continue to drive biodiversity loss and greenhouse gas (GHG) emissions. Food retailers play a key but currently understudied and underleveraged role in shifting consumer habits away from foods with high climate and biodiversity impacts (e.g. beef, lamb, milk) towards lower-impact alternatives. Through partnering with a Swedish food retailer and
The present study explores how Danish-Iranian Women living in Copenhagen witness and take part in the connective Woman Life Freedom movement, online and from afar. It seeks to investigate their emotional engagement with Instagram, their political participation and their sense of belonging in this process. With a media studies perspective, the study works in the intersection between civic engagemen
As plastic pollution in aquatic environments keeps happening it has become more and more important to learn more about nanoparticles. Bio-based and biologically degradable plastics, such as polylactic acid (PLA), are gaining popularity and it is therefore important to determine whether they break down into nanoplastics or not. Should this be the case, it is of interest to characterize their size,
This study has examined Liberian disabled women’s participation in peace and security processes through the lens of the United Nations Security Council Resolution (UNSCR) 1325. The aim was to gain new insights into Liberian disabled women’s experience in peace and security processes, since the overarching research problem is the lack of insight into the disabled women’s experiences as participants
In 2000, the Clinton Administration in the U.S. adopted the Commodity Futures Modernization Act, which deregulated the U.S. trade with financial instruments on commodity markets. With respect to this adoption, it has been regarded as one catalyst for the Global food crisis 2008, where millions of individuals lacked provision and access to agricultural products and nutrition. From the perspective o
