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OBJECTIVE - Whole-grain foods are touted for multiple health benefits including enhancing insulin sensitivity and reducing type 2 diabetes risk Recent genome-wide association studies (GWAS) have identified several single nucleotide polymorphisms (SNPs) associated with fasting glucose and insulin concentrations in individuals free of diabetes We tested the hypothesis that whole-grain food intake an
BACKGROUND: Advanced glycation end products (AGE) and their receptors (RAGE) have been implicated in cancer development through their proinflammatory capabilities. However, prospective data on their association with cancer of specific sites, including pancreatic cancer, are limited.METHODS: Prediagnostic blood levels of the AGE product Nε-(carboxymethyl)lysine (CML) and the endogenous secreted rec
This thesis will look at the profession of Town Planning from an economic perspective utilising New Institutional Economics (NIE) to focus on how different institutions and structures bring about efficiency trade- offs. As planning systems have considerable influence over property rights (the ability to affect one‟s own lands) and over transaction costs by intervening in land markets, planning ins
Avskogning är ett globalt problem och har många negativa effekter. Det största hotet mot skogen är dessvärre människan. Trots ökade satsningar på hållbar skogshantering och skogsvård så fortsätter avverkningen av skog i snabb takt världen över, för att ge plats åt andra typer av markanvändning så som jordbruks- och betesmark. Världens population fortsätter att öka och Afrika är den kontinent med sDeforestation is a widespread problem and has many negative impacts. The biggest threat to forest is human activities. Despite increasing efforts regarding forest management and forest conservation, the deforestation continues at a high rate to give space for other land uses such as agriculture and pasture. The world’s population continues to grow and Africa is the continent with fastest growing p
For the last couple of years, the popularity of e-bikes has grown substantially. Thanks to the electric motor people can now ride uphill and longer distances without arriving at their destination sweaty and exhausted. But even if the function of electric bikes is great I saw problems in the design of the bikes that are currently on the market. Problems that made them very unattractive for
The hedge fund industry has become one of the most creative and innovative areas within banking and finance during the past ten years. Its rapid growth and constant development has made it hard for regulators to mitigate the potential risks posed to investors and the financial system. The aim of this thesis is to discuss the potential need for further regulation of hedge funds, mainly based on the
The aim of the study was to complement dual labor market research by qualitatively exploring how labor market segmentations may be understood beyond sociodemographics or inequalities of job quality. By interviewing 12 Swedish workers with wage subsidies I have found that access to high job quality may facilitate trajectories towards primary market sectors, but they are only relevant so far as the
Today, more and more consumers are asking brands to take a stand on socio-political issues in order to generate a values-based connection with consumers. However, most previous research has focused only on individual brand activism, with little attention paid to co-branding brand activism. Through the co-branding case of Dove and The Body Shop, this study aims to understand how Dove framed its col
One third of Sweden's total annual greenhouse gas emissions originate from the transport sector today and great changes are thus needed in order to reach the net zero emission target by 2045. One of the most important measures discussed is an increased electrification of the transport sector and a solution with potential to contribute to this transition is electric road systems (ERS), where ve
This thesis examines the role of public servants in official development assistance (ODA), a form of foreign aid administered by states. While research on foreign aid highlights its potential to improve living conditions, it also reveals issues of ineffectiveness and overconfidence within the aid sector. Moreover, certain forms of foreign aid continued and can still continue to perpetuate colonial
Popular Abstract in Swedish Sophia Elisabeth Brenner (1659-1730) var Sveriges första stora kvinnliga poet. Hon var verksam som författare och lärd kvinna under femtio år, och var dessutom en flitig brevskrivare. Avhandlingen baseras på en inventering av bevarade brev till och från Sophia Brenner skrivna på latin, svenska, franska och italienska. Hennes nylatinska korrespondens med danske Otto SpeSophia Elisabeth Brenner (1659-1730) was Sweden's first great female poet, writing and publishing her poems over a period of fifty years. She was also, however, a prolific letter writer. The dissertation is based on an inventory of all the preserved letters to and from her written in Latin, Swedish, French and Italian. Her Neo-Latin correspondence with the Dane Otto Sperling the Younger is presen
Objective: To investigate the relationship between early-onset retinopathy and urinary markers of renal dysfunction. Research Design and Methods: The Diabetes Incidence Study in Sweden (DISS) aims to register all new cases of diabetes in young adults (15-34 years). In 1987-1988, 806 patients were reported and later invited to participate in a follow-up study focusing on microvascular complications
The entire cDNA corresponding to the C-terminal cysteine-rich domain of the human MUC2 apomucin, after the serine- and threonine-rich tandem repeat, was expressed in Chinese-hamster ovary-K1 cells and in the human colon carcinoma cell line, LS 174T. The C-terminus was expressed as a fusion protein with the green fluorescent protein and mycTag sequences and the murine immunoglobulin K-chain signal
The increase in Ca(2+)-activated force caused by polyamines in beta-escin-permeabilized guinda pig ileum is shown to be associated with increased myosin 20-kDa light chain (LC20) phosphorylation and shortening velocity. Myosin LC20 dephosphorylation with arrested kinase activity was slower in the presence of 1 mM spermine. Smooth muscle phosphatases (SMP-I, -II, -III, and -IV) isolated from turkey
Recently, common noncoding variants in the TCF7L2 gene were strongly associated with increased risk of type 2 diabetes in samples from Iceland, Denmark, and the U.S. We genotyped 13 single nucleotide polymorphisms (SNPs) across TCF7L2 in 8,310 individuals in family-based and case-control designs from Scandinavia, Poland, and the U.S. We convincingly confirmed the previous association of TCF7L2 SNP
