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Affinity fractionation of lymphocytes using a monolithic cryogel.

A new type of continuous, supermacroporous, monolithic, cryogel affinity adsorbent was developed, allowing specific fractionation and separation of human peripheral blood lymphocytes in a chromatographic format. The affinity adsorbent was used to design a novel cell separation strategy, which was based on the interaction of protein A from Staphylococcus aureus with cells bearing IgG antibodies on

Secure Cloud Control Using Verifiable Computation

Security for outsourced control applications can be provided if the physical plant is enabled with a mechanism to verify the control signal received from the cloud. Recent developments in modern cryptography claim the applicability of verifiable computation techniques. Such techniques allow a client to check the correctness of a remote execution. This article delivers a proof of concept for applic

Personalized Seizure Detection Using Spiking Neural Networks

Around 50 million people worldwide suffer from Epilepsy, making it one of the most common neurological diseases. Epilepsy is characterized by sudden intermittent seizures, often imposing profound social and physical limitations. More importantly, the risk of premature death in these patients is up to three times that of the corresponding healthy population. It is estimated that 30% of the populati

Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes

Background. Anti-glomerular basement membrane (anti-GBM) disease often results in end-stage renal failure despite therapy with plasma exchange and immunosuppressive drugs. The newly discovered streptococcal enzymes IgG-degrading enzyme of S.pyogenes (IdeS) and endoglycosidase S (EndoS) act with remarkable specificity on circulating IgG. In this study, we investigate their ability in vivo to preven

A Simulation Study Quantifying the Effects of Drive Cycle Characteristics on the Performance of a Pneumatic Hybrid Bus

In the study presented in this paper, the effect of different vehicle driving cycles on the pneumatic hybrid has been investigated. The pneumatic hybrid powertrain has been modeled in UT-Power and validated against experimental data. The GT-Power engine model has been linked with a MATLAB/simulink vehicle model. The engine in question is a single-cylinder Scania D12 diesel engine, which has been c

Interaction of Nanometric Clay Platelets

The free energy of interaction between two nanometric clay platelets immersed in an electrolyte solution has been calculated using Monte Carlo simulations as well as direct integration of the configurational integral. Each platelet has been modeled as a collection of charged spheres carrying a unit charge-the face of a platelet contains negative charges, and the edge, positive charges. The calcula