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GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65

GAD65 autoantibodies (GAD65Ab) are highly prevalent in type 1 diabetes, but their functional role in the pathogenesis of the disease and their relationship to T-cell reactivity to GAD65 is still unclear. We tested the hypothesis that GAD65Ab modulate presentation of GAD65 to T-cells. T-cell hybridoma T33.1, which recognizes the GAD65 274-286 epitope in the context of HLA-DRB1*0401, was incubated w

Geol01-installation av endnote

Microsoft Word - GEOL01Installation av EndNote-2.docx Installation av EndNote För att ladda ner EndNote, gå till Studentportalen (via Lunds universitets hemsida, välj Student, sedan Studentportalen, eller http://www.student.lu.se/uPortal/render.userLayoutRootNode.uP) Logga in med ditt Stil-id. Välj Mina tjänster, sedan Hämta programvaror. Gör du detta när du befinner dig utanför Lunds universitets

https://www.geology.lu.se/sites/geology.lu.se/files/geol01-installation_av_endnote.pdf - 2026-06-08

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The aim of present study was to arrange an experimental rabbit model for IgA-nephropathy. To this purpose, an approach was attempted which was previously successfully applied in rabbits, aiming for induction of post-streptococcal glomerulonephritis (PSGN). To induce the nephropathy, we used two Streptococcus pyogenes strains of M4 and M60 serotypes which showed differential IgA-binding capacity me

Luca Margaritella

Biträdande universitetslektor Kontaktinformation E-post: luca [dot] margaritella [at] nek [dot] lu [dot] seOrganisation Nationalekonomiska institutionen Hämtställe: 10 WebbplatsLuca Margaritellas profil i Lunds universitets forskningsportal Publikationer Visar av publikationer. Sorterade efter år och sen titel. Filtrera efter typ AllaArtikel i tidskrift Filtrera Estimating Aggregate Relationships

https://www.ehl.lu.se/luca-margaritella - 2026-06-07

IdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G.

Recent work from several laboratories has demonstrated that proteolytic mechanisms significantly contribute to the molecular interplay between Streptococcus pyogenes, an important human pathogen, and its host. Here we describe the identification, purification and characterization of a novel extracellular cysteine proteinase produced by S.pyogenes. This enzyme, designated IdeS for Immunoglobulin G-

Verksamhetsberattelse 2017 for eds nordic user group

Bilaga 1 Verksamhetsberättelse 2017 för EDS Nordic User Group Vid EDS Nordic User Groups årsmöte 2017-03-22 i Luleå valdes följande styrelsemedlemmar: ordförande Cilla Öhnfeldt, Stockholms universitet (omval), Per Falk, Högskolan i Gävle (nyval), Ann- Christin Persson, Lunds universitet (nyval), Tove Andersson, Region Skåne (nyval), Mikael Arvidsson, Karlstads universitet (omval) och Eva Sejmyr, L

https://www.ub.lu.se/sites/ub.lu.se/files/verksamhetsberattelse_2017_for_eds_nordic_user_group.pdf - 2026-06-08

Charging of aerosol particles - An investigation of the possibility of using Americium-241 for SMPS chargers

Climate change is a fact and effects everybody on this planet, whether its humans, plants or animals. There is a comprehensive agreement about the mechanisms on how aerosol particles affect the radiative balance of the earth, but there is a need of more knowledge to fully understand climate change and the strength of the aerosol radiative forcing. The aim of this thesis is to investigate if the SM