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Studies on hereditary C2 deficiency: Frequent occurrence of severe infections, atherosclerosis and rheumatological manifestations

Popular Abstract in Swedish Komplementsystemet utgör en del av den medfödda immuniteten och är viktigt i försvaret mot angripande mikroorganismer. Ärftlig C2-brist (C2D) är en av de vanligaste bristerna inom komplementsystemet och förekommer i en frekvens av 1: 20 000 hos personer med västerländsk härstamning. I de aktuella undersökningarna har mer än 40 personer med C2D identifierats och observerThe complement system is a part of the innate immunity and is essential in the defence against microorganisms. Hereditary C2 deficiency (C2D) is one of the most common complement deficiency states with an estimated prevalence of 1:20,000 in persons of Western descent. In the present investigation, the identification of more than 40 C2D persons at a single centre combined with long observation peri

Exploring Processor and Memory Architectures for Multimedia

Popular Abstract in English Consumption of multimedia content is one of the main tasks we perform in our day-to- day lives, such as listening to music on an iPod or watching the news from an online steaming service. As technology has evolved and enabled easier access to different content (basically access anything anywhere), our consumption has grown. In only the last decades we have evolved from Multimedia has become one of the cornerstones of our 21st century society and, when combined with mobility, has enabled a tremendous evolution of our society. However, joining these two concepts introduces many technical challenges. These range from having sufficient performance for handling multimedia content to having the battery stamina for acceptable mobile usage. When taking a projection of w

Lika Villkorsplan 2022-2027 Tillg

Lika villkorsplan 2022-2027 för naturvetenskapliga fakulteten Lika villkorsplan. NATURVETENSKAPLIGA FAKULTETEN | 2022–2027 | STYR 2022/2575 2 LIKA VILLKORSPLAN MED AKTIVA ÅTGÄRDER Innehåll. Förord Bakgrund OBLIGATORISKA BYGGSTENAR .......................................................... 4 REKOMMENDERADE OMRÅDEN .......................................................... 4 SYSTEMATISKT ARBETE MED

https://www.naturvetenskap.lu.se/internt/sites/naturvetenskap.lu.se.internt/files/2023-03/Lika%20villkorsplan%202022-2027%20tillg.pdf - 2026-05-22

Tentamen

OBS Nya rutiner för salstentamen från och med ht25! Praktisk information om vad som gäller för salstentor och hemtentor på psykologprogrammet SalstentamenNya regler för salstentamen:- Från och med höstterminen 2025, ht25, kommer alla salstentamina att skrivas i lokaler på Annexet och Sparta och där gäller deras regler. Läs mer på deras hemsida - Tentamen i Annexet och på Sparta | Lunds universitet

https://www.psy.lu.se/utbildning/dig-som-ar-student-vara-utbildningar/psykologprogrammet/tentamen - 2026-05-21

Tuning the Electronics of Bis(tridentate)ruthenium(II) Complexes with Long-Lived Excited States: Modifications to the Ligand Skeleton beyond Classical Electron Donor or Electron Withdrawing Group Decorations

A series of homoleptic bis(tridentate) [Ru-(L)(2)](2+) (1, 3) and heteroleptic [Ru(L)(dqp)](2+) complexes (2, 4) [L = dqxp (1, 2) or dNinp (3, 4); dqxp = 2,6-di(quinoxalin-5-yl)pyridine, dNinp = 2,6-di(N-7-azaindol-1-yl)pyridine, dqp = 2,6-di(quinolin-8-yl)pyridine) was prepared and in the case of 2 and 4 structurally characterized. The presence of dqxp and dNinp in 1-4 result in anodically shifte

Gränö 750 ME: En Modulär Elektrisk Motorbåt för morgondagen.

The aim for this report is to present an industrial design master thesis carried out by Micael Palmgren at Lunds University. The report describes, not only the end result of the project, but also the path along the line to the final result. The master thesis have developed and visualized a unique concept for a new motorboat for tomorrow, called Gränö 750 ME. The reader will be taken through the de

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Course Analysis for MATA31 Analysis in One Variable, Autumn 2024 Course information Lecturer: Jan-Fredrik Olsen Teaching assistants: Thomas Munn, Alex Bergman, Erik Troedsson, Frej Dahlin Number of students: 96 newly registered and 0 re-registered. 39 students answered the course evaluation. An additional 5 responded to an ‘old’ version of the course evaluation form that was erroneously available

https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/HT2024/MATA31HT24.pdf - 2026-05-21

Structural determination of Streptococcus pyogenes M1 protein interactions with human immunoglobulin G using integrative structural biology

Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi

Efficacy of T-cell assays for the diagnosis of primary defects in cytotoxic lymphocyte exocytosis

Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe

Group G streptococcal IgG binding molecules FOG and protein G have different impacts on opsonization by C1q

Recent epidemiological data on diseases caused by beta-hemolytic streptococci belonging to Lancefield group C and G ( GCS, GGS) underline that they are an emerging threat to human health. Among various virulence factors expressed by GCS and GGS isolates from human infections, M and M-like proteins are considered important because of their anti-phagocytic activity. In addition, protein G has been i

Potentialities of manganese ore and iron-carbon particles for pharmaceuticals and personal care products removal in electroactive constructed wetland

This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo

Development and validation of a novel Simoa assay for NPTX2 in Alzheimer's disease and Down syndrome

INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w

Results of a phase I/II study of ocrelizumab, a fully humanized anti-CD20 mAb, in patients with relapsed/refractory follicular lymphoma

Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

Streptococcus pyogenes secreted enzymes interacting with the human host

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Paul Pierce

Senior lecturer Contact details Email: paul [dot] pierce [at] ics [dot] lu [dot] seOrganisation Department of Informatics Room number: EC2-225 Service point: 10 WebpagePaul Pierces profile in Lund University research portal Publications Displaying of publications. Sorted by year, then title. Filter by type AllBook chapterConference paperDissertationJournal articleReport Filter Unveiling digitalisa

https://www.lusem.lu.se/paul-pierce - 2026-05-21

Defining extended half-life rFVIII-A critical review of the evidence

Introduction: Recent haemophilia treatment advances include new recombinant FVIII (rFVIII) products with improved pharmacokinetic (PK) properties that aim to reduce the burden of prophylaxis. These treatments are commonly referred to as extended half-life rFVIII products (EHL rFVIII). There is no uniform definition of what constitutes an EHL rFVIII. Such a definition would help physicians, patient