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Background: We were concerned that a fixed rather than a weight-based dosing regimen of dalteparin sodium to prevent venous thromboembolism. (VTE) might result in decreased efficacy in obese patients and decreased safety in elderly patients. Methods: We retrospectively performed subgroup analyses using the database from the Prospective Evaluation of Dalteparin Efficacy for Prevention of VTE in Imm
While current instruments of EU economic policy coordination helped stave off a full- scale depression, the post-2007 global financial and economic crisis has revealed a number of weaknesses in the Stability and Growth Pact, the EU framework for fiscal surveillance and fiscal policy coordination. This paper provides a diagnosis of how the SGP faired ahead and during the present crisis and offers a
Objectives: The optimal treatment of latent autoimmune diabetes in adults (LADA) is not established. We explored whether early insulin treatment, which has shown beneficial effects in rodents and in human pilot studies, would result in better preservation of beta-cell function or metabolic control, compared with conventional treatment. Subjects and methods: Glucagon-stimulated C-peptide and HbAlc
This study delineates the permissible scope for compulsory mental health interventions under the Convention on the Rights of Persons with Disabilities (CRPD). It was initially triggered by two competing positions within the current debate over the future of coercive psychiatry; a practice that is still omnipresent among states worldwide. According to one position, defended by the CRPD Committee amThis study delineates the permissible scope for compulsory mental health interventions under the Convention on the Rights of Persons with Disabilities (CRPD). It was initially triggered by two competing positions within the current debate over the future of coercive psychiatry; a practice that is still omnipresent among states worldwide. According to one position, defended by the CRPD Committee am
In Sweden, various public health interventions have been performed to reduce risky sexual behaviors among young people and promote safer and positive approaches to sexuality, while attempting to bridge the gap between the less privileged or more vulnerable young people and their more privileged peers. This study aimed to compare the individual- and familial-level determinants of risky sexual behav
The captive bubble method was used to describe the wetting characteristics of a number of commercial ultrafiltration (UF) membranes. The membranes belonged to one of two homologous (same material, different cut-off) series made by the same manufacturer. One series was made of polysulphone and the other one of cellulose triacetate. The porosimetric characteristics of the membranes have also been me
The aim of the paper is to discuss, with a broadly postcolonial sensibility, the complex role that language has come to play in the contemporary process of globalization. It attempts to show that language, besides being a medium of communication, has come to play a crucial role in companies’ conquest of the global market, on the one hand, and in defending a general idea of an imaginary homogenous
Epidural anesthesia is a common pain relief method that has grown in popularity over the last few decades. It is administered into the epidural space, a narrow compartment within the spinal canal. The space is localized by inserting a needle between the vertebrae. Due to the sudden loss of resistance upon entering the epidural space, combined with its narrow diameter, the procedure is difficult t
Epigenetic modifications influence gene expression and contribute to type 2 diabetes (T2D), but establishing causality requires targeted modulation of specific genes. CRISPR-dCas9-based tools offer this potential, yet β-cells are notoriously difficult to transfect, and efficient, non-viral delivery methods are lacking. Here, we developed nanopore-mediated electroporation to deliver a CRISPR interf
Min avhandling är en undersökning av civilsamhälleliga aktörers vardagliga erfarenheter av hur väpnad konflikt, utvinningsindustri och motstånd har format det colombianska Andinoamazonia under landets pågående fredsbyggande process. Trots ett tjugotal fredsavtal och undertecknandet av ett övergripande avtal 2016 har Colombias långvariga väpnade konflikt inte upphört. Det colombianska AndinoamazoniMy thesis is an inquiry into the daily experiences of civil society actors in relation to how armed conflict, extractivism, and resistance shaped the Colombian Andinoamazonia during the country’s current peacebuilding cycle. Despite two dozen peace agreements, and the signing of a comprehensive agreement in 2016, Colombia’s protracted armed conflict did not end. The Colombian Andinoamazonia, a bio
This master's thesis explores the potential of integrating floating wind power into Power-to-X (P2X) megaprojects, with a focus on maximizing the output of chemical energy carriers through optimal energy mix strategies. The study evaluates the economic viability and technological efficiency of combining floating wind turbines with photovoltaic panels and battery energy storage systems (BESS) i
Liturgical life in today's Catholic Church in the Western world is dominated by women, alt-hough the priesthood remains reserved for men. Conservative critics speak of a feminization of worship life, which is said to be a consequence of the liturgical reform implemented after the Second Vatican Council in the 1960s. This movement gained traction in academic youth circles, and although women also j
Introduction Mechanical ventilation can be monitored by analysing particles in exhaled air as measured by particle flow rate (PFR). This could be a potential method of detecting ventilator-induced lung injury (VILI) before changes in conventional parameters can be detected. The aim of this study was to investigate PFR during different ventilation modes in patients without lung pathology. Method A
Two acid deposition scenarios were simulated for six European forest sites situated in Germany, Denmark, Russia, Switzerland, Spain and Ireland. Three models were used in combination; the RAINS (Regional Acidification INformations and Simulation) model, the SAFE (Simulating Acidification in Forest Ecosystems) model and the MakeDep model. The scenarios used were based on results from international
Resolved NMR spectra from samples in inhomogeneous B-0 and B-1 fields can be obtained with the so-called "ex situ" methodology, employing a train of composite or adiabatic z-rotation RF pulses to periodically refocus the inhomogeneous broadening during the detection of the time-domain signal. Earlier schemes relied on a linear correlation between the inhomogeneous B0 and B, fields. Here the pulse
Popular Abstract in Swedish Infektiös hepatit eller gulsot kan orsakas av flera olika sorters virus. De har alla det gemensamt att de orsakar en inflammation av levern. Namnet gulsot kommer av att när leverns funktion nedsätts så ansamlas ett färgämne i kroppen och ger ögonvitorna och huden en synlig gulgrön färg. Efter hand som de olika gulsotsvirusen har upptäckts har de namngivits efter alfabetHepatitis B virus is a non-cytopathic virus with a small, circular, partially double-stranded DNA of 3.2 kb. It causes acute and chronic inflammatory liver disease and hepatocellular carcinoma (HCC). Retesting of stored sera from an outbreak of acute hepatitis in 1969-72 allowed identification of 126 cases of acute hepatitis B. No chronic carriers expressing hepatitis B surface antigen (HBsAg) cou
Background While transcatheter aortic valve implantation (TAVI) is established for treating highoperative risk surgical aortic valve replacement candidates, until recently the smallest transcatheter heart valve (THV) measured 23 mm, posing greater risk for annular rupture and THV failure in patients with aortic stenosis (AS) with small aortic annuli (=20 mm). Objectives In the setting of a multice
On 26 May 2016 the Court of Justice of the EU (CJEU) decided Bookit Ltd v HMRC (Bookit)1 which dealt with the interpretation of the exemption for transactions concerning payments within article 135(1)(d) of the Council Directive on the common system of value added tax (the VAT Directive).2 Article 135(1)(d) of the VAT Directive provides that Member States shall exempt "transactions, including nego
This dissertation discusses employer run or supported occupational pension schemes. Special attention is given to the question of employers' pension promises, their portability and security, during the first half of the 20:th century in Sweden. How did occupational pensions in private industry change in quantitative terms? What did the terminology of a pension promise, its portability and security
