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CCL25/CCR9 promotes the induction and function of CD103 on intestinal intraepithelial lymphocytes.

The integrin CD103 and the chemokine receptor CCR9 are co-expressed on small intestinal CD8+ intraepithelial lymphocytes (IEL), naïve murine CD8+ T cells and by a small population of effector/memory CD8+ T cells, indicating a potential role for CCR9 in regulating CD103 expression and function. Here, we demonstrate that CD103, in contrast to CCR9, is down-regulated on CD8+ T cells following their a

Protein D of Haemophilus influenzae. A novel bacterial surface protein with affinity for human IgD

Protein D, a novel surface protein of the bacterial species Haemophilus influenzae with affinity for human IgD, was isolated after solubilization with sonication and Sarcosyl-extraction by a single SDS-PAGE step. From 1 ml of packed bacteria was prepared 0.25 mg of purified protein D. The apparent m.w. of protein D was estimated to 42,000 by SDS-PAGE and gel chromatography. Edman degradation cycle

Focus Asia 2006

26-27 April & 22-23 November Religious and Social movements in East and South-East AsiaOn 26 April the lectures addressed new developments and research regarding the social and political role of religion in contemporary East and South-East Asian societies. In China and Japan we see a revival of religion and a redefinition of religion as a result of both domestic and global developments. In the Sou

https://www.ace.lu.se/activities/selected-past-events/focus-asia/focus-asia-2006 - 2026-05-15

Express cohort - epihealth map 2014 km

PowerPoint-presentation Swedish EXPRESS Study Karel Maršál Department of Obstetrics and Gynecology Lund University, Sweden Swedish national prospective study Extremely Preterm Infants in Sweden (EXPRESS) Inclusion criteria: • All live-born infants < 27 gestational weeks • Stillbirths 22+0 – 26+6 weeks April 1, 2004 – March 31, 2007 Exclusion criteria: • Births outside Sweden • Pregnancy terminatio

https://www.epihealth.lu.se/sites/epihealth.lu.se/files/express_cohort_-_epihealth_map_2014_km.pdf - 2026-05-16

Culture night at the Botanical Garden

Botanical Garden offers knowledge as well as wonderful experiences! Botanize among the variety of vegetables, participate in activities for both children and adults, and enjoy with all your senses in beautiful surroundings. Apart from the bird guide, all activities during Culture Night in Botan are gathered in an area that stretches from the southern part of the garden up towards the kitchen garde

https://www.botan.lu.se/en/culture-night-botanical-garden - 2026-05-15

LU-gemensamt Mejlutskick Nr 9-v10-2021

NYTT FRÅN LUNDS UNIVERSITET Mejlutskick på svenska och engelska som vänder sig till fakultetskommunikatörer vid Lunds universitet för vidarespridning i fakultets- och institutionskanaler – Nr 9 v 10 - 2021. CORONARELATERAT Vårterminen 2021 får förlängas Den pågående pandemin skapar fortsatt problem med att genomföra vissa utbildningsmoment, bland annat verksamhetsförlagd utbildning. Sektion Studen

https://www.cec.lu.se/sites/cec.lu.se/files/2021-03/LU-gemensamt%20Mejlutskick%20Nr%209-v10-2021.pdf - 2026-05-16

Genetic control of collagen-induced arthritis in a cross with NOD and C57Bl/10 mice is dependent on gene regions coding for complement factor 5 and FcγRIIb and is not associated with loci controlling diabetes.

The nonobese diabetic (NOD) mouse spontaneously develops autoimmune-mediated diseases such as diabetes and Sjögren′s syndrome. To investigate whether NOD genes also promote autoimmune-mediatedarthritis we established a NOD strain with an MHC class II fragment containing the Aq class II gene predisposing for collagen induced arthritis (NOD.Q). However, this mouse was resistant to arthritis in contr

New perspectives on complement mediated immunotherapy

Tumor-specific monoclonal antibodies (mAbs) offer several modes of tumor cell killing, from direct cytotoxic activity to indirect mechanisms employing the host immune system, particularly its innate branch. The latter effector functions seem to dominate among clinically approved anti-cancer mAbs and major efforts are being undertaken by both academia and the pharmaceutical industry with the aim to

Analysis of the molecular interplay between Streptococcus pyogenes and its human host

The common human pathogen Streptococcus pyogenes is the causative agent of numerous mild and severe clinical conditions. It expresses a number of secreted or cell wall-anchored proteins that modulate the human immune system and facilitate colonization and spread of the pathogen in the human host. During S. pyogenes infections, human plasma leaks into the site of infection as a consequence of infl

Evasion of phagocytosis through cooperation between two ligand-binding regions in Streptococcus pyogenes M protein.

The M protein of Streptococcus pyogenes is a major bacterial virulence factor that confers resistance to phagocytosis. To analyze how M protein allows evasion of phagocytosis, we used the M22 protein, which has features typical of many M proteins and has two well-characterized regions binding human plasma proteins: the hypervariable NH2-terminal region binds C4b-binding protein (C4BP), which inhib

Derivation of efficiency factors for uneven irradiation on a fin absorber

In the equation for thermal energy output from a flat-plate solar collector (written as a function of the collector mean heat carrier temperature), both the gain and the loss terms are multiplied by the collector efficiency factor, F'. For a concentrating collector with an uneven (non-uniform) irradiation on the absorber, the efficiency factor for the gain term, here called the optical efficiency

Eosinophil granulocyte interaction with serum-opsonized particles: binding and degranulation are enhanced by tumor necrosis factor alpha

Eosinophils participate in the inflammatory response seen in allergy and helminthic infestation. Their release of granule-bound cationic proteins may play a role in these diseases. Therefore, we investigated mechanisms involved in the release of eosinophil cationic protein (ECP). Serum-opsonized zymosan was phagocytosed by eosinophils, and ECP was released into the phagosomes as judged by immunoel

Two major classes in the M protein family in group A streptococci

The M protein family of molecules in the group A streptococcus comprises a number of cell surface proteins that interact with the immune system of the host. One of the proteins in this family is the IgA receptor Arp4, which has C repeats similar to those that characterize the known M proteins. The streptococcal strain expressing Arp4 also expresses a second immunoglobulin-binding protein, Mrp4, wh